Zobrazeno 1 - 10
of 2 280
pro vyhledávání: '"Richard David"'
Autor:
Jean Van Rampelbergh, Peter Achenbach, Richard David Leslie, Martin Kindermans, Frédéric Parmentier, Vincent Carlier, Nicolas Bovy, Luc Vanderelst, Marcelle Van Mechelen, Pierre Vandepapelière, Christian Boitard
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background IMCY-0098, a synthetic peptide developed to halt disease progression via elimination of key immune cells in the autoimmune cascade, has shown a promising safety profile for the treatment of type 1 diabetes (T1D) in a recent phase
Externí odkaz:
https://doaj.org/article/3ea8c33bb1fa4f08a58cae9c56d17631
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2024)
ObjectivesEvidence suggests that emotional awareness—the ability to identify and label emotions—may be impaired in schizophrenia and related to positive symptom severity. Exposure to childhood maltreatment is a risk factor for both low emotional
Externí odkaz:
https://doaj.org/article/13cb6e66e3a5426281a2d0f11e21c10f
Publikováno v:
Revista Científica de FAREM-Estelí, Vol 12, Iss 48 (2024)
El presente artículo tiene como objetivo analizar la relación del estrés laboral y el síndrome metabólico en el personal que labora en una Clínica Médica Laboral Nicaragua, marzo-abril del 2022. Se desarrolló un estudio cuantitativo de tipo d
Externí odkaz:
https://doaj.org/article/4545c8e1cb614861ad10b550cbed3afe
Publikováno v:
Bulletins et Mémoires de la Société d’Anthropologie de Paris, Vol 36 (2023)
Externí odkaz:
https://doaj.org/article/51560ad5364e42eebf773bdb6f9bdeec
Autor:
Macarena Giselle Picos-Salas, Edwin Canon-Buitrago, Richard David Rios-Cruz, Micaela Brun Lomado
Publikováno v:
Revista de Instrumentos, Modelos e Políticas em Avaliação Educacional, Vol 4 (2023)
Este estudio tuvo como objetivo comprender la forma como el profesional de Educación Física moviliza estrategias metodológicas para desarrollar su accionar docente con niños con síndrome de Down en la ciudad de Paysandú-Uruguay. Tratase de una
Externí odkaz:
https://doaj.org/article/78cc406e00fc4b6e9b2c8eb8e03d80f4
Autor:
Jean Van Rampelbergh, Peter Achenbach, Richard David Leslie, Mohammad Alhadj Ali, Colin Dayan, Bart Keymeulen, Katharine R. Owen, Martin Kindermans, Frédéric Parmentier, Vincent Carlier, Roxana R. Ahangarani, Evelien Gebruers, Nicolas Bovy, Luc Vanderelst, Marcelle Van Mechelen, Pierre Vandepapelière, Christian Boitard
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Type 1 diabetes (T1D) is a CD4+ T cell-driven autoimmune disease characterized by the destruction of insulin-producing pancreatic β-cells by CD8+ T cells. Achieving glycemic targets in T1D remains challenging in clinical practice
Externí odkaz:
https://doaj.org/article/143d6c1cb5cb44809e4416a40ebd193d
Autor:
Xiang Yan, Xia Li, Bingwen Liu, Jiaqi Huang, Yufei Xiang, Yuhang Hu, Xiaohan Tang, Ziwei Zhang, Gan Huang, Zhiguo Xie, Houde Zhou, Zhenqi Liu, Xiangbing Wang, Richard David Leslie, Zhiguang Zhou
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-9 (2023)
Abstract Disease modifying therapies aiming to preserve β-cell function in patients with adult-onset autoimmune type 1 diabetes are lacking. Here, we conducted a multi-centre, randomized, controlled trial to assess the β-cell preservation effects o
Externí odkaz:
https://doaj.org/article/09df3a80cbe14b24aec4eed0319c5852
Autor:
Shangyu Chai, Ruya Zhang, Richard David Carr, Carolyn F. Deacon, Yiman Zheng, Swapnil Rajpathak, Jingya Chen, Miao Yu
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
AimsGlucose-dependent insulinotropic polypeptide (GIP) confers a variety of metabolic benefits in type 2 diabetes mellitus (T2DM). This meta-analysis was conducted to investigate the impact of dipeptidyl peptidase 4 (DPP4) inhibitors on GIP levels in
Externí odkaz:
https://doaj.org/article/c5d6fcb6c29c4a16a44ab5511b0fe22d
Autor:
Han Nim Lee, Jenu Varghese Chacko, Ariadna Gonzalez Solís, Kuo-En Chen, Jessica AS Barros, Santiago Signorelli, A Harvey Millar, Richard David Vierstra, Kevin W Eliceiri, Marisa S Otegui
Publikováno v:
eLife, Vol 12 (2023)
The ubiquitin-binding NBR1 autophagy receptor plays a prominent role in recognizing ubiquitylated protein aggregates for vacuolar degradation by macroautophagy. Here, we show that upon exposing Arabidopsis plants to intense light, NBR1 associates wit
Externí odkaz:
https://doaj.org/article/93f424ab5f8e497193b96a33063af471
Publikováno v:
Bulletins et Mémoires de la Société d’Anthropologie de Paris, Vol 35 (2023)
Externí odkaz:
https://doaj.org/article/115aa7c6aa804255847ed8e74088e00c