Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Richard Danger"'
Autor:
Adrien Tissot, Eugénie Durand, Thomas Goronflot, Benjamin Coiffard, Benjamin Renaud-Picard, Antoine Roux, Xavier Demant, Jean-François Mornex, Loïc Falque, Mathilde Salpin, Jérôme Le Pavec, Thomas Villeneuve, Véronique Boussaud, Christiane Knoop, Antoine Magnan, David Lair, Laureline Berthelot, Richard Danger, Sophie Brouard, the COLT consortium
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Long-term outcomes of lung transplantation (LTx) remain hampered by chronic lung allograft dysfunction (CLAD). Matrix metalloproteinase 9 (MMP-9) is a secretory endopeptidase identified as a key mediator in fibrosis processes asso
Externí odkaz:
https://doaj.org/article/40b383908c3243b6a59278ac8664cad1
Autor:
Esteban Cortes Garcia, Alessia Giarraputo, Maud Racapé, Valentin Goutaudier, Cindy Ursule-Dufait, Pierre de la Grange, Lucie Adoux, Marc Raynaud, Clément Couderau, Fariza Mezine, Jessie Dagobert, Oriol Bestard, Francesc Moreso, Jean Villard, Fabian Halleck, Magali Giral, Sophie Brouard, Richard Danger, Pierre-Antoine Gourraud, Marion Rabant, Lionel Couzi, Moglie Le Quintrec, Nassim Kamar, Emmanuel Morelon, François Vrtovsnik, Jean-Luc Taupin, Renaud Snanoudj, Christophe Legendre, Dany Anglicheau, Klemens Budde, Carmen Lefaucheur, Alexandre Loupy, Olivier Aubert
Publikováno v:
Transplant International, Vol 37 (2024)
Recently, interest in transcriptomic assessment of kidney biopsies has been growing. This study investigates the use of NGS to identify gene expression changes and analyse the pathways involved in rejection. An Illumina bulk RNA sequencing on the pol
Externí odkaz:
https://doaj.org/article/9ecc3009d82f4404afee19ecf718e603
Autor:
Nicolas Sailliet, Amandine Dupuy, François Brinas, Karine Renaudin, Luc Colas, Clarisse Kerleau, Thi-Van-Ha Nguyen, Cynthia Fourgeux, Jérémie Poschmann, Clément Gosset, Magali Giral, Nicolas Degauque, Hoa Le Mai, Richard Danger, Sophie Brouard
Publikováno v:
Cells, Vol 13, Iss 15, p 1287 (2024)
The aim of our study was to determine whether granzyme B-expressing regulatory B cells (GZMB+ B cells) are enriched in the blood of transplant patients with renal graft tolerance. To achieve this goal, we analysed two single-cell RNA sequencing (scRN
Externí odkaz:
https://doaj.org/article/aa73797a72844d32a155d0443f3fbd31
Autor:
Nicolas Sailliet, Hoa-Le Mai, Amandine Dupuy, Gaëlle Tilly, Cynthia Fourgeux, Martin Braud, Magali Giral, Jean-Michel Robert, Nicolas Degauque, Richard Danger, Jeremie Poschmann, Sophie Brouard
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionHuman Granzyme B (GZMB) regulatory B cells (Bregs) have suppressive properties on CD4+ effector T cells by a mechanism partially dependent on GZMB. Moreover, these cells may be easily induced in vitro making them interesting for cell ther
Externí odkaz:
https://doaj.org/article/fd8ac4765aaa4e34853bc71dad38a34f
Autor:
Annick Massart, Richard Danger, Catharina Olsen, Mary J. Emond, Ondrej Viklicky, Valérie Jacquemin, Julie Soblet, Sarah Duerinckx, Didier Croes, Camille Perazzolo, Petra Hruba, Dorien Daneels, Ben Caljon, Mehmet Sukru Sever, Julio Pascual, Marius Miglinas, the Renal Tolerance Investigators, Isabelle Pirson, Lidia Ghisdal, Guillaume Smits, Magali Giral, Daniel Abramowicz, Marc Abramowicz, Sophie Brouard, Maria Aguilar Rodríguez, Friederike Bachmann, Rajendra Bahadur Shahi, Frederike Bemelman, Luboslav Bena, Luigi Biancone, Laura Braun, Klemens Budde, Alejandro Camargo-Salamanca, Katia Clemente, Hulya Colak, Adrian Covic, Jacques Degreve, Philippe Gatault, François Glowacki, Karine Hadaya, Marc Hazzan, Bénédicte Janbon, Christophe Legendre, Umberto Maggiore, Anja Mühlfeld, Maarten Naesens, Christian Noël, Rainer Oberbauer, Evangeline Pillebout, Gian Benedetto Piredda, Francesco Pisani, Ana Ramírez Puga, Tomas Reischig, Francisco González-Roncero, Søren Schwartz Sørensen, Daniel Seron Micas, Nurhan Seyahi, Dimitrie Siriopol, Goce Spasovski, Jean-François Subra, Erik Teugels, Serhan Tuǧlular, Sonia Van Dooren, Catheline Vilain, Florence Villemain, Xavier Warling, Bruno Watschinger, Laurent Weekers
Publikováno v:
Frontiers in Medicine, Vol 9 (2023)
BackgroundRenal operational tolerance is a rare and beneficial state of prolonged renal allograft function in the absence of immunosuppression. The underlying mechanisms are unknown. We hypothesized that tolerance might be driven by inherited protein
Externí odkaz:
https://doaj.org/article/728d19d9593f48acbfe88073eed48e31
Autor:
Hoa Le Mai, Nicolas Degauque, Marine Lorent, Marie Rimbert, Karine Renaudin, Richard Danger, Clarisse Kerleau, Gaelle Tilly, Anaïs Vivet, Sabine Le Bot, Florent Delbos, Alexandre Walencik, Magali Giral, Sophie Brouard
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe human immune system contains cells with either effector/memory or regulatory functions. Besides the well-established CD4+CD25hiCD127lo regulatory T cells (Tregs), we and others have shown that B cells can also have regulatory function
Externí odkaz:
https://doaj.org/article/c88d9c9bbb964e658df20ca7a76e4bae
Autor:
Christophe Pison, Adrien Tissot, Eric Bernasconi, Pierre-Joseph Royer, Antoine Roux, Angela Koutsokera, Benjamin Coiffard, Benjamin Renaud-Picard, Jérôme Le Pavec, Pierre Mordant, Xavier Demant, Thomas Villeneuve, Jean-Francois Mornex, Simona Nemska, Nelly Frossard, Olivier Brugière, Valérie Siroux, Benjamin J. Marsland, Aurore Foureau, Karine Botturi, Eugenie Durand, Johann Pellet, Richard Danger, Charles Auffray, Sophie Brouard, Laurent Nicod, Antoine Magnan, Members of the Cohort of Lung Transplantation and Systems prediction of Chronic Lung Allograft Dysfunction consortia
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundChronic lung allograft dysfunction (CLAD) is the leading cause of poor long-term survival after lung transplantation (LT). Systems prediction of Chronic Lung Allograft Dysfunction (SysCLAD) aimed to predict CLAD.MethodsTo predict CLAD, we i
Externí odkaz:
https://doaj.org/article/68b4df3b02c74cd8bf8582c9d8c3772c
Autor:
Hoa Le Mai, Nicolas Degauque, Sabine Le Bot, Marie Rimbert, Karine Renaudin, Richard Danger, Florent Le Borgne, Clarisse Kerleau, Gaelle Tilly, Anaïs Vivet, Florent Delbos, Alexandre Walencik, Magali Giral, Sophie Brouard
Publikováno v:
EBioMedicine, Vol 83, Iss , Pp 104226- (2022)
Summary: Background: CD28-CD8+ T cells represent a differentiated CD8+ T cell subset that is found to be increased in various conditions associated with chronic antigenic stimulation such as aging, chronic viral infections, autoimmune diseases, cance
Externí odkaz:
https://doaj.org/article/58d1684669a64d518878509727335a7f
Autor:
Ludmilla Le Berre, Mélanie Chesneau, Richard Danger, Florian Dubois, Damien Chaussabel, Mathieu Garand, Sophie Brouard
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BANK1 transcript is upregulated in whole blood after kidney transplantation in tolerant patients. In comparison to patients with rejection, tolerant patients display higher level of regulatory B cells (Bregs) expressing granzyme B (GZMB+) that have t
Externí odkaz:
https://doaj.org/article/ff07b236dc8946228f982e86e956fe94
Autor:
Richard Danger, Quentin Moiteaux, Yodit Feseha, Estelle Geffard, Gérard Ramstein, Sophie Brouard
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0261083 (2021)
Web-based data analysis and visualization tools are mostly designed for specific purposes, such as the analysis of data from whole transcriptome RNA sequencing or single-cell RNA sequencing. However, generic tools designed for the analysis of common
Externí odkaz:
https://doaj.org/article/da7c654f8a39478bab08e269f382fbab