Copy number and transcriptome alterations associated with metastatic lesion response to treatment in colorectal cancer

Autor: Karen Gambaro, Maud Marques, Suzan McNamara, Mathilde Couetoux du Tertre, Zuanel Diaz, Cyrla Hoffert, Archana Srivastava, Steven Hébert, Benoit Samson, Bernard Lespérance, Yoo‐Joung Ko, Richard Dalfen, Eve St‐Hilaire, Lucas Sideris, Felix Couture, Ronald Burkes, Mohammed Harb, Errol Camlioglu, Adrian Gologan, Vincent Pelsser, André Constantin, Celia M.T. Greenwood, Sabine Tejpar, Petr Kavan, Claudia L. Kleinman, Gerald Batist

Publikováno v: Clinical and Translational Medicine, Vol 11, Iss 4, Pp n/a-n/a (2021)

Abstract Background Therapeutic resistance is the main cause of death in metastatic colorectal cancer. To investigate genomic plasticity, most specifically of metastatic lesions, associated with response to first‐line systemic therapy, we collected

Externí odkaz: https://doaj.org/article/2db15e511b2048da941740287e8636c1

External beam accelerated partial breast irradiation versus whole breast irradiation after breast conserving surgery in women with ductal carcinoma in situ and node-negative breast cancer (RAPID): a randomised controlled trial

Autor: Barbara Strang, Michelle Bishop, Radhika Yelamanchili, Maria Vlachaki, Jon-Paul Voroney, Keith Tankel, Tanya Berrang, Wayne Koll, Jonathan Wan, Tarek Hijal, André Fortin, Francois Germain, David Nguyen, Vikash Patel, D. Voduc, Michael Lock, Janice Giesbrecht, Ivo A. Olivotto, Anupam Chaudhuri, Aisling Barry, Sophie Lavertu, D.I. Hodson, Chakiath Jose, Elaine Sze-Sze Wai, Paul-Émile Raymond, Bashir Bashir, Dorianne Elizabeth Rheaume, Farah Naz, Alan Nichol, David W. Petrik, Hosam (Sam) Kader, Pierre Chabot, Marjory Jolicoeur, Kalyani Vijayraghavan, Vamsee Torri, Caroline Chung, Woodrow A. Wells, Theresa Trotter, Susan Tyler, Boon Chua, Eric Vigneault, Martin Samosh, Hedley Krawitz, Susan Chafe, Philip Hughes, Isabelle Roy, Holly Campbell, Ken I. Mills, Sonia Nguyen, John Radwan, Som D. Mukherjee, Jim A. Julian, Lucie Blondeau, Jonathan Sussman, Khalil Sultanem, Christina Kim, Marie-Andrée Fortin, Nathalie Lessard, Isabelle Vallieres, Darin Gopaul, Fleur Huang, Mira Keyes, Jacqueline Lam, Celine Lemaire, Beverly Helen Lester, Kurian Joseph, Aminudin Rahman Mohd Mydin, Karen Chu, Maged Nashed, Carson Leong, Susan Gudelis, Michael Levesque, Wilson H. Miller, H. Abu-Zahra, Isabelle Germain, Brian Dingle, David Want, Mark Levine, Andre-Guy Martin, Robert E. Dinniwell, Ethel MacIntosh, Kathy Han, Mary K. Dwyer, Sudha Purchuri, Jennifer Goulart, Mohamed Akra, Hugh L. Prichard, Ken Schneider, Sarwat Shehata, S. Eshwar Kumar, Juanita Mary Crook, J. Bowen, Sally Smith, Benjamin Goldenberg, Michael Yassa, Michael Sia, Thierry Muanza, Harold I. Reiter, Peter Lim, Yongjin Wang, Bassam Abdul Karim, Medhat Zikry Abd-El-Malek, Wayne Beckham, Khalid Hirmiz, David D'Souza, Ruth Angell, Joanne Meng, Pierre Rousseau, Maha Almahmudi, Jose Ayllon, Paris-Ann Ingledew, Bernd Esche, Zsolt Gabos, Ramesh Arunachalam, Steven David, Olga Vujovic, Marc David, Lee Manchul, Chen Liu, William McMillan, Neil Kopek, Lorraine Walsh, Joycelin Canavan, Arthur Cheung, Claire Philips, JD (Jidong) Lian, Joelle Helou, Christine Elder, Caroline Holloway, Ian S. Dayes, Sawyna Provencher, Robert Olson, Christina Aquino Parsons, Medhat El-Mallah, Wladyslawa Cwajna, Francisco Perera, Gillian Campbell, Senti Senthelal, Christine Anne Koch, Paul Ahlgren, Peter S. Craighead, Nancy Grant, Julianna Caon, Brian Yaremko, Jasper Yuen, Fawaad Iqbal, Elizabeth Yan, Timothy J. Whelan, Suki Gill, Adrian Langleben, Richie Sinha, Chu Shu Gu, Pauline T. Truong, Wilfred Levin, Negin Shahid, Christopher Ford, Elizabeth Saettler, Pierre Del Vecchio, Thomas McGowan, David Wasserman, Do Hoon Kim, James Pinilla, Scott Morgan, Luis-Victor Diaz de Bedoya, Krystine Lupe, Roger Huang, Luleul Khan, Annie Carbonneau, Vimoj Nair, Behzad (Sayed) Banihashemi, Melanie Reed, Marisa Finlay, Steven Latosinsky, Charles Hayter, Peter Vavassis, Frances Lai-Wah Wong, Ramana Rachakonda, Levon Igidbashian, Andrew Cooke, Marie Larochelle, Susan Brooks, B. Findlay, Anne Dagnault, Sachi Voruganti, Olivier Ballivy, Jean-Marc Bourque, Rachel VanderMeer, Edward Yu, M.D. Mohiuddin, Jawaid Younus, Tracy Sexton, Rachel Bujold, Yiu-Keung (James) Lau, Catherine Lochrin, Glenn Jones, Paul Blood, Sofya Kobeleva, Glenys Round, Niluja Thiruthaneeswaran, Scott Tyldesley, Susan Balkwill, Michael J. McLean, J.A. (Jack) MacKinnon, Islam Gharib Mohamed, Catalin Mihalioiu, Bronwyn King, Sundeep Shahi, Philip C. Chan, Melanie Gaudreault, Samy El-Sayed, Dominique Lee, Diane Marie Severin, Tatiana Conrad, John Amanie, Christine Lambert, Linda Lee, Winkle Kwan, Annie Ebacher, Youssef M. Youssef, Paul Genest, Chang Shu Wang, Fei-Fei Liu, Jean-Pierre Guay, B.C. John Cho, Pamela Catton, Thayavalappil Hemanth, Tien Phan, Peter H. Dixon, Peter Cross, Roslyn Drummond, Abdenour Nabid, Joel Broomfield, Abraham Alexander, Theodore A. Vandenberg, Giuseppe Sasso, Barbara Krause, Marianne Krahn, Jimmy Mui, Nancy Read, Jane Wilson, Francois Patenaude, Cathy Menkarios, Nadeem Pervez, Donna Stern, Solveig Grenfell, Robert Nordal, Anthony Fyles, Valerie Panet-Raymond, David Melnychuk, James G. Wright, Vasanth Basrur, Toni Vu, Richard Dalfen, Maria Pearse, Valérie Théberge, Jonathan Tsao, Adam Andronowski, Hannah Mills Carolan, Chelleraj Benjamin, Lawrence Panasci, Robert Rutledge, Tracie Gleisner, Randall Bissett, Maureen C. Nolan, Lorna Weir, Siraj Husain, Laval Grimard, Jean-Michel Caudrelier, Francis Methot, Kylea Potvin

Publikováno v: The Lancet. 394:2165-2172

Summary Background Whole breast irradiation delivered once per day over 3–5 weeks after breast conserving surgery reduces local recurrence with good cosmetic results. Accelerated partial breast irradiation (APBI) delivered over 1 week to the tumour

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::071e7156cc73848103b6676794743345
https://doi.org/10.1016/s0140-6736(19)32515-2

A Pilot Randomized Controlled Trial on the Effects of a Progressive Exercise Program on the Range of Motion and Upper Extremity Grip Strength in Young Adults With Breast Cancer

Autor: Warren Sateren, Mary-Ann Dalzell, Beatrice Fournier, Petr Kavan, Marize Ibrahim, Richard Dalfen, Thierry Muanza, Michael Palumbo, Nadia Smirnow

Publikováno v: Clinical Breast Cancer. 18:e55-e64

Background The diagnosis of breast cancer in young women (aged 18-45 years) has been increasing. Women are commonly left coping with treatment-related disabilities of the upper limb that can persist for > 2 years postoperatively. Patients and Methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21a4dff7bb28c2b9356b9cfe05d5b18
https://doi.org/10.1016/j.clbc.2017.06.007

Time course of upper limb function and return-to-work post-radiotherapy in young adults with breast cancer: a pilot randomized control trial on effects of targeted exercise program

Autor: Warren Sateren, Nadia Smirnow, Michael Palumbo, Beatrice Fournier, Marize Ibrahim, Mary-Ann Dalzell, Richard Dalfen, Petr Kavan, Thierry Muanza

Publikováno v: Journal of cancer survivorship : research and practice. 11(6)

Breast cancer (BC) diagnosis in young adults (YA) is rising, and both disease and treatments are aggressive in this population. Evidence supports the use of physical activity in reducing shoulder dysfunction, which is common among BC survivors. A pil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea0ee84d1b48ad020cab3a2d31f9ac5d
https://pubmed.ncbi.nlm.nih.gov/28470507

Copy number variation in longitudinal liver metastases biopsies in colorectal cancer identifies biomarker candidates of resistance to standard chemotherapy

Autor: Archana Srivastava, Félix Couture, Benoit Samson, Suzan McNamara, Y-J. Ko, Mohammed Harb, Richard Dalfen, Errol Camlioglu, Vincent Pelsser, Ronald L. Burkes, Maud Marques, Adrian Gologan, Karen Gambaro, Sabine Tejpar, Gerald Batist, Eve St-Hilaire, Lucas Sideris, Bernard Lespérance, Claudia L. Kleinman, Cyrla Hoffert, M. Couetoux du Tertre, Petr Kavan

Publikováno v: Annals of Oncology. 30:iv133

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2a3c051aaab387fa6d809a3bfeaf0856
https://doi.org/10.1093/annonc/mdz154.019