Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Richard Dahl"'
Autor:
Mike Khan, Jerome S Harms, Yiping Liu, Jens Eickhoff, Jin Wen Tan, Tony Hu, Fengwei Cai, Erika Guimaraes, Sergio Costa Oliveira, Richard Dahl, Yong Cheng, Delia Gutman, Glen N Barber, Gary A Splitter, Judith A Smith
Publikováno v:
PLoS Pathogens, Vol 16, Iss 10, p e1009020 (2020)
Brucellosis, caused by a number of Brucella species, remains the most prevalent zoonotic disease worldwide. Brucella establish chronic infections within host macrophages despite triggering cytosolic innate immune sensors, including Stimulator of Inte
Externí odkaz:
https://doaj.org/article/d2b3bfb878264b17877fb7ed40ea6334
Publikováno v:
Cancers, Vol 13, Iss 2, p 274 (2021)
Ovarian cancer (OC) cells survive in the peritoneal cavity in a complex microenvironment composed of diverse cell types. The interaction between tumor cells and non-malignant cells is crucial to the success of the metastatic process. Macrophages acti
Externí odkaz:
https://doaj.org/article/3aa7afb4152d4ca6a039e6c0704d55c3
Autor:
Jeffrey L Kurkewich, Justin Hansen, Nathan Klopfenstein, Helen Zhang, Christian Wood, Austin Boucher, Joseph Hickman, David E Muench, H Leighton Grimes, Richard Dahl
Publikováno v:
PLoS Genetics, Vol 13, Iss 7, p e1006887 (2017)
MicroRNA cluster mirn23a has previously been shown to promote myeloid development at the expense of lymphoid development in overexpression and knockout mouse models. This polarization is observed early in hematopoietic development, with an increase i
Externí odkaz:
https://doaj.org/article/8d28755ad5454c348ffa81e4b29f53b8
Autor:
Jeffrey L Kurkewich, Nathan Klopfenstein, William M Hallas, Christian Wood, Rachel A Sattler, Chhaya Das, Haley Tucker, Richard Dahl, Karen D Cowden Dahl
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161468 (2016)
Arid3a and Arid3b belong to a subfamily of ARID (AT-rich interaction domain) transcription factors. The Arid family is involved in regulating chromatin accessibility, proliferation, and differentiation. Arid3a and Arid3b are closely related and share
Externí odkaz:
https://doaj.org/article/5ceb529aeaee474cbd4dc9258760b72b
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 11, Pp 1208-1215 (2009)
The epithelial-to-mesenchymal transition (EMT) that occurs during embryonic development is recapitulated during tumor metastasis. Important regulators of this process include growth factors, transcription factors, and adhesion molecules. New evidence
Externí odkaz:
https://doaj.org/article/04a320d3f3c5492f87664bc45244ce84
Publikováno v:
PLoS Genetics, Vol 11, Iss 1, p e1004959 (2015)
Overexpression of miRNA, miR-24, in mouse hematopoietic progenitors increases monocytic/ granulocytic differentiation and inhibits B cell development. To determine if endogenous miR-24 is required for hematopoiesis, we antagonized miR-24 in mouse emb
Externí odkaz:
https://doaj.org/article/1b371bb1931043b2b3ff82801b62a9c9
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55406 (2013)
The microRNA, miR-24, inhibits B cell development and promotes myeloid development of hematopoietic progenitors. Differential regulation of cell survival in myeloid and lymphoid cells by miR-24 may explain how miR-24's affects hematopoietic progenito
Externí odkaz:
https://doaj.org/article/60b538b809c547a197260422e6ca13ac
Autor:
Andrew Appert, Sridhar Rao, Seok Hee Jang, Richard Dahl, Nathan Klopfenstein, William Morgan Hallas, Kirthi Pulakanti, Karen D. Cowden Dahl, Austin Boucher, Jennifer Skibbe
Publikováno v:
J Immunol
Macrophages are critical for regulating inflammatory responses. Environmental signals polarize macrophages to either a proinflammatory (M1) state or an anti-inflammatory (M2) state. We observed that the microRNA (miRNA) cluster mirn23a, coding for mi
Autor:
Shirng-Wern Tsaih, Anupallavi Srinivasamani, Angela Lemke, Sridhar Rao, Subramaniam Malarkannan, Arash Nanbakhsh, Sandra L. Holzhauer, Robert Burns, Michael Reimer, Yongwei Zheng, Michael J. Flister, Shunhua Lao, Monica S. Thakar, Matthew J. Riese, Richard Dahl, Demin Wang
Publikováno v:
Cancer Immunology Research. 7:1647-1662
Natural killer (NK) cells generate proinflammatory cytokines that are required to contain infections and tumor growth. However, the posttranscriptional mechanisms that regulate NK cell functions are not fully understood. Here, we define the role of t
Publikováno v:
Cancers
Volume 13
Issue 2
Cancers, Vol 13, Iss 274, p 274 (2021)
Volume 13
Issue 2
Cancers, Vol 13, Iss 274, p 274 (2021)
Simple Summary Ovarian cancer is the 5th leading cause of cancer death in US women, due to late diagnosis. The vast majority of patients with ovarian cancer have metastatic disease at diagnosis, leading to poor survival. As the tumor cells metastasiz