Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Richard D. Lozano"'
Autor:
Yehuda Z. Patt, Thomas A. Aloia, James L. Abbruzzese, Jean Nicolas Vauthey, Hesham M. Hassabo, Manal M. Hassan, Richard D. Lozano, Junichi Shindoh, Robert E. Roses, Ahmed Kaseb, Steven A. Curley, Giuseppe Zimmitti
Publikováno v:
Cancer. 119:3334-3342
BACKGROUND The purpose of this study was to evaluate the factors associated with response rate, resectability, and survival after cisplatin/interferon α-2b/doxorubicin/5-fluorouracil (PIAF) combination therapy in patients with initially unresectable
Autor:
Richard D. Lozano, Judith A. Smith, Justin M. Julius, Anjali Gaikwad, Robert L. Coleman, Amy Lowry, Russell E. Lewis, John L. Dalrymple
Publikováno v:
Journal of Antimicrobial Chemotherapy. 67:422-429
Objectives To determine whether the catechol functional group on echinocandins decreases the catechol-O-methyltransferase (COMT) metabolism of catechol oestrogens (CEs) and the potential role of this functional group in the development of hepatocellu
Autor:
Vikas Kumar, Lianchun Xiao, Ahmed Kaseb, Jeffrey S. Morris, E. Lin, James L. Abbruzzese, Manal M. Hassan, Richard D. Lozano, Asif Rashid, Priyanka Pathak
Publikováno v:
Cancer. 117:2478-2488
BACKGROUND: Several staging systems have been proposed for hepatocellular carcinoma (HCC); however, none has incorporated circulating angiogenic biomarkers. The purpose of this study was to determine whether vascular endothelial growth factor (VEGF)
Autor:
Richard D. Lozano, Yehuda Z. Patt, Isaac I. Schnirer, Ajay K. Nooka, Manal M. Hassan, Jerome B. Zeldis, Thomas Brown, James L. Abbruzzese
Publikováno v:
Cancer. 103:749-755
BACKGROUND The treatment of patients with hepatocellular carcinoma (HCC) presents a major challenge, because associated cirrhosis limits the choice of chemotherapeutic agents. However, the abundant vascularity of HCC presents an attractive target for
Autor:
Douglas B. Evans, Robert A. Wolff, Jaffer A. Ajani, James C. Yao, Maria A. Kouvaraki, Paulo M. Hoff, Richard D. Lozano
Publikováno v:
Journal of Clinical Oncology. 22:4762-4771
Purpose The role of systemic chemotherapy in the management of pancreatic endocrine carcinoma (islet cell carcinoma; PEC) is an area of considerable controversy. Response rates ranging from 6% to 69% have been reported for streptozocin-based chemothe
Autor:
Stanley R. Hamilton, Melanie B. Thomas, Richard D. Lozano, Eric D. Tetzlaff, Eddie K. Abdalla, Charles E. Butler, Jean Nicholas Vauthey, Christopher J. Gannon, Leigh A. Samp
Publikováno v:
Journal of Surgical Oncology. 97:82-84
Hepatocellular carcinoma (HCC) that present as hemoperitoneum are uncommon, often recur as peritoneal carcinomatosis, and have poor prognosis. Systemic chemotherapies are minimally effective in advanced HCC and less so as neo-adjuvant therapy. This r
Publikováno v:
Journal of Clinical Oncology. 14:2306-2310
PURPOSE To evaluate the efficacy of paclitaxel administered to patients with unresectable adenocarcinomas of the gallbladder and biliary tree over 3 hours every 21 days. PATIENTS AND METHODS Fifteen patients with unresectable and/or metastatic carcin
Autor:
Avi B. Markowitz, Richard D. Lozano, Chuslip Charnsangavej, Yehuda Z. Patt, A. Hoque, Patrick M. Lynch, I. Raijman, Delrose Jones
Publikováno v:
Journal of Clinical Oncology. 14:2311-2315
PURPOSE To assess the efficacy of systemic intravenous-fluorouracil (5-FU) and subcutaneous recombinant human interferon alfa-2b (rIFN alpha-2b) in patients with measurable cancer of the biliary tree. PATIENTS AND METHODS Thirty-five patients (25 wit
Publikováno v:
Investigational New Drugs. 19:341-343
Purpose. Severe diarrhea can represent adose-limiting toxicity with the use ofCPT-11. Conventional therapy isineffective in some patients and is alsolimited by patient compliance. We reportour observation on the effectiveness ofoctreotide acetate in
Autor:
Marta L. Davila, Milind Javle, Richard D. Lozano, Dalia M. Moghazy, Manal M. Hassan, Ahmed Kaseb, Jean Nicolas Vauthey, James L. Abbruzzese, Eddie K. Abdalla, Donghui Li, Steven A. Curley
Publikováno v:
Cancer. 116(8)
BACKGROUND: Despite the observed association between diabetes mellitus and hepatocellular carcinoma (HCC), little is known about the effect of diabetes duration before HCC diagnosis and whether some diabetes medications reduced the risk of HCC develo