Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Richard D. Kelsey"'
Publikováno v:
Tetrahedron Letters. 51:6806-6809
A tandem decomplexation-nitroso Diels-Alder (decomplexation-NDA) procedure has been shown to give the regiocontrol and stereocontrol needed for application in an organoiron-mediated synthesis of the alkaloid hippeastrine, using a selection of nitroso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0aeb502e29c204ee197e3a09e8f26a6d
https://doi.org/10.1016/j.tetlet.2010.09.118
https://doi.org/10.1016/j.tetlet.2010.09.118
Publikováno v:
Organic Letters. 7:713-716
Electrophilic amination of primary aliphatic and aromatic amines is reported using a diethylketomalonate-derived oxaziridine to afford the corresponding N-Boc hydrazines in good to excellent yields. The method allows a one-pot synthesis of pyrazoles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58d4d43a444448b1a29e2c9b4b0e5060
https://doi.org/10.1021/ol0474507
https://doi.org/10.1021/ol0474507
Autor:
Alan Armstrong, Richard D. Kelsey, Trevor J. Critchley, Andrew A. Mortlock, Marie-Edith Gourdel-Martin
Publikováno v:
Tetrahedron Letters. 43:6027-6030
Synthesis of the γ-lactone unit of CP-225,917 and CP-263,114 is reported by differentiation of a diester at C14 using either selective monohydrolysis or lactonisation of a C26-alcohol.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c2606046de45eb69eac54608ea724e6
https://doi.org/10.1016/s0040-4039(02)01243-1
https://doi.org/10.1016/s0040-4039(02)01243-1
Autor:
Marie-Edith Gourdel-Martin, Richard D. Kelsey, Trevor J. Critchley, Andrew A. Mortlock, Alan Armstrong
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :1344-1350
A concise synthesis of the bicyclo[4.3.1]dec-1(9)-en-10-one core of the natural products CP-225,917 and CP-263,114 is reported, employing an intramolecular Mukaiyama aldol cyclisation as a key step.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efe0a636fa2fd4bae6a99ddd18dcf873
https://doi.org/10.1039/b202752f
https://doi.org/10.1039/b202752f
Autor:
Richard D. Kelsey, Trevor J. Critchley, Andrew A. Mortlock, Marie-Edith Gourdel-Martin, Alan Armstrong
Publikováno v:
ChemInform. 33
A concise synthesis of the bicyclo[4.3.1]dec-1(9)-en-10-one core of the natural products CP-225,917 and CP-263,114 is reported, employing an intramolecular Mukaiyama aldol cyclisation as a key step.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2dcac41d305e72205363c4f2b021dd7
https://doi.org/10.1002/chin.200240237
https://doi.org/10.1002/chin.200240237
Publikováno v:
Polyhedron. 19:569-571
The heterocycloaddition reaction between nitrosobenzene and 2-methylcyclohexa-1,3-diene preferentially affords the regioisomer with the N-Ph group next to the methyl substituent, and this product has been characterised by X-ray crystallography. As a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0948d7ae4fe7fb74f776399e77245f2f
https://doi.org/10.1016/s0277-5387(99)00410-6
https://doi.org/10.1016/s0277-5387(99)00410-6
Autor:
Dagmar Alber, G. Stuart Cockerill, Jeremy N. Stables, Kenneth L. Powell, Verity C. L. Dowdell, Richard D. Kelsey, Sian K. Bithell, James Lumley, Ann Chubb, Robert Alan Harris, Robert C. Baxter, Elisa Henderson, Natasha Weerasekera, Joanna Budworth, Ian J Fraser, Lara J. Wilson, Malcolm Clive Carter, Sally J. Keegan
Publikováno v:
Journal of medicinal chemistry. 50(7)
Respiratory syncytial virus (RSV) is the cause of one-fifth of all lower respiratory tract infections worldwide and is increasingly being recognized as representing a serious threat to patient groups with poorly functioning or immature immune systems
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d27cc877fe8ac62cbc5c1e4b79f51be1
https://pubmed.ncbi.nlm.nih.gov/17341059
https://pubmed.ncbi.nlm.nih.gov/17341059
Autor:
Joanna Chapman, Raymond J. Pickles, Malcolm Clive Carter, Sian K. Bithell, Debbie Taylor, Dagmar Alber, Michael J. Lockyer, Kenneth L. Powell, Mark Simmonds, Elisa Henderson, Elizabeth Abbott, Robert C. Baxter, Cindy Luongo, Pilar Najarro, Verity C. L. Dowdell, Peter L. Collins, Lara J. Wilson, Stan Tyms, Sally J. Keegan, Phil Chambers, Ann Chubb, G. Stuart Cockerill, Richard D. Kelsey
Respiratory syncytial virus (RSV) is the most common cause of lower respiratory tract infections worldwide, yet no effective vaccine or antiviral treatment is available. Here we report the discovery and initial development of RSV604, a novel benzodia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a1158d584e34da009ece04bfe7b723
Publikováno v:
Tetrahedron Letters. 40:147-148
The aluminium chloride catalysed Friedel-Crafts reaction between adipoyl chloride and bromobenzene has been re-examined. At elevated temperatures a number of side products are produced including a cyclopentane epoxide. The structure of this epoxide w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c21fd08a7b7d60e4bab9294356dacd3e
https://doi.org/10.1016/s0040-4039(98)80043-9
https://doi.org/10.1016/s0040-4039(98)80043-9
Autor:
Elisa A. Henderson, Dagmar G. Alber, Robert C. Baxter, Sian K. Bithell, Joanna Budworth, Malcolm C. Carter, Ann Chubb, G. Stuart Cockerill, Verity C. L. Dowdell, Ian J. Fraser, Robert A. Harris, Sally J. Keegan, Richard D. Kelsey, James A. Lumley, Jeremy N. Stables, Natasha Weerasekera, Lara J. Wilson, Kenneth L. Powell
Publikováno v:
Journal of Medicinal Chemistry; Apr2007, Vol. 50 Issue 7, p1685-1692, 8p