Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Richard D. Harland"'
Publikováno v:
Alcoholism: Clinical and Experimental Research. 19:1234-1245
Increased recognition of the advantages of genetic animal models has led to heightened interest in their use and development. A replicated bidirectional selective breeding project has produced lines of mice that differ in their locomotor responses to
Publikováno v:
Psychopharmacology. 109(1-2)
Acquisition and retention of tolerance to ethanol's rate-decreasing effects on operant performance were examined in rats which received a 52-day regimen of ethanol or saline injections prior to and/or after each daily session. Eight groups of rats di
Publikováno v:
Drug Development Research. 16:183-194
When contrasting drugs (i.e., chlordiazepoxide versus pentylenetetrazol) are examined in drug-drug, drug-saline, or drug 1-drug 2-saline tasks, one can begin to assess whether such drugs represent orthogonal cues or reflect an underlying cue dimensio
Autor:
Ron C. Michaelis, Thomas W. Seale, John M. Carney, Richard D. Harland, Frank A. Holloway, David V. Gauvin
Publikováno v:
Pharmacology Biochemistry and Behavior. 32:1017-1023
The effects of caffeine upon the discriminative and rate-altering effects of cocaine were examined in rats. Using a food-reinforced two-lever operant procedure, 12 Sprague-Dawley male rats were trained to discriminate between 10 mg/kg cocaine and sal
Publikováno v:
Psychopharmacology. 99(4)
The effects of pre-session and post-session daily ethanol injections on the development and loss of tolerance to ethanol's effects on fixed ratio operant performance in rats was assessed using a cumulative dosing procedure. Daily pre-session ethanol
Publikováno v:
Drug and alcohol dependence. 24(2)
Twelve male Sprague-Dawley rats were trained in a standard two-choice Drug 1-Drug 2 discrimination task utilizing 3.0 mg/kg chlordiazepoxide (CDP, an anxiolytic drug) and 20 mg/kg pentylenetetrazol (PTZ, an anxiogenic drug) as discriminative stimuli
Autor:
Richard D. Harland, Ron C. Michaelis, Alice M. Holohean, Jose R. Criado, George A. Hunter, Frank A. Holloway
Publikováno v:
Psychopharmacology. 96(1)
Rats were trained to discriminate chlordiazepoxide (CDP) from pentylenetetrazol (PTZ) in a two-lever food motivated discrimination task. Training drug doses were adjusted until subjects emitted approximately 50% of their responses on each of the two