Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Richard D. Emes"'
Autor:
Rodhan Patke, Anna E. Harris, Corinne L. Woodcock, Rachel Thompson, Rute Santos, Amber Kumari, Cinzia Allegrucci, Nathan Archer, Lorraine J. Gudas, Brian D. Robinson, Jenny L. Persson, Rupert Fray, Jennie Jeyapalan, Catrin S. Rutland, Emad Rakha, Srinivasan Madhusudan, Richard D. Emes, Musalwa Muyangwa-Semenova, Mansour Alsaleem, Simone de Brot, William Green, Hari Ratan, Nigel P. Mongan, Jennifer Lothion-Roy
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 56, Iss , Pp 101032- (2024)
Prostate cancer (PCa) is the second most common cancer diagnosed in men. While radical prostatectomy and radiotherapy are often successful in treating localised disease, post-treatment recurrence is common. As the androgen receptor (AR) and androgen
Externí odkaz:
https://doaj.org/article/f224ca60609a48d0bd38942bd1a03543
Autor:
Reinhard Stöger, Minseung Choi, Khurshida Begum, Gregory Leeman, Richard D. Emes, Philippa Melamed, Gillian R. Bentley
Publikováno v:
Epigenetics, Vol 18, Iss 1 (2023)
Migration from one location to another often comes with a change in environmental conditions. Here, we analysed features of DNA methylation in young, adult British-Bangladeshi women who experienced different environments during their childhoods: a) m
Externí odkaz:
https://doaj.org/article/6a8804a212804b47bf7beb3e15d70cdf
Autor:
Desmond A. R. Tutt, Gizem Guven-Ates, Wing Yee Kwong, Rob Simmons, Fei Sang, Giuseppe Silvestri, Carla Canedo-Ribeiro, Alan H. Handyside, Remi Labrecque, Marc-André Sirard, Richard D. Emes, Darren K. Griffin, Kevin D. Sinclair
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundIn vitro maturation (IVM) of germinal vesicle intact oocytes prior to in vitro fertilization (IVF) is practiced widely in animals. In human assisted reproduction it is generally reserved for fertility preservation or where ovarian stimulati
Externí odkaz:
https://doaj.org/article/af282c29578c47c285ffd4ead6fbbbbe
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/139229deb8a345658f98afddbd5140b7
Autor:
Jennifer Lothion-Roy, Daisy B. Haigh, Anna E. Harris, Veronika M. Metzler, Mansour Alsaleem, Michael S. Toss, Yousif Kariri, Atara Ntekim, Brian D. Robinson, Francesca Khani, Lorraine J. Gudas, Cinzia Allegrucci, Victoria H. James, Srinivasan Madhusudan, Melissa Mather, Richard D. Emes, Nathan Archer, Rupert G. Fray, Emad Rakha, Jennie N. Jeyapalan, Catrin S. Rutland, Nigel P. Mongan, Corinne L. Woodcock
Publikováno v:
Frontiers in Genetics, Vol 13 (2023)
N6-methyladenosine (m6A) is the most abundant internal mRNA modification and is dynamically regulated through distinct protein complexes that methylate, demethylate, and/or interpret the m6A modification. These proteins, and the m6A modification, are
Externí odkaz:
https://doaj.org/article/ee16cd5a10274e0e9f3c44999cecb5f8
Autor:
Ben Bar-Sadeh, Or E. Amichai, Lilach Pnueli, Khurshida Begum, Gregory Leeman, Richard D. Emes, Reinhard Stöger, Gillian R. Bentley, Philippa Melamed
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background Women facing increased energetic demands in childhood commonly have altered adult ovarian activity and shorter reproductive lifespan, possibly comprising a strategy to optimize reproductive success. Here, we sought to understand t
Externí odkaz:
https://doaj.org/article/53f5872b9f984e2581c2aab71505b831
Autor:
Michelle Baker, Alexander D. Williams, Steven P.T. Hooton, Richard Helliwell, Elizabeth King, Thomas Dodsworth, Rosa María Baena-Nogueras, Andrew Warry, Catherine A. Ortori, Henry Todman, Charlotte J. Gray-Hammerton, Alexander C.W. Pritchard, Ethan Iles, Ryan Cook, Richard D. Emes, Michael A. Jones, Theodore Kypraios, Helen West, David A. Barrett, Stephen J. Ramsden, Rachel L. Gomes, Chris Hudson, Andrew D. Millard, Sujatha Raman, Carol Morris, Christine E.R. Dodd, Jan-Ulrich Kreft, Jon L. Hobman, Dov J. Stekel
Publikováno v:
Environment International, Vol 169, Iss , Pp 107516- (2022)
Waste from dairy production is one of the largest sources of contamination from antimicrobial resistant bacteria (ARB) and genes (ARGs) in many parts of the world. However, studies to date do not provide necessary evidence to inform antimicrobial res
Externí odkaz:
https://doaj.org/article/d61615982ed441efa5676391502a6507
Autor:
Martin J. Blythe, Ayhan Kocer, Alejandro Rubio-Roldan, Tom Giles, Abdulkadir Abakir, Côme Ialy-Radio, Lee M. Wheldon, Oxana Bereshchenko, Stefano Bruscoli, Alexander Kondrashov, Joël R. Drevet, Richard D. Emes, Andrew D. Johnson, John R. McCarrey, Daniel Gackowski, Ryszard Olinski, Julie Cocquet, Jose L. Garcia-Perez, Alexey Ruzov
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Blythe et al investigate the patterns of oxidized forms of the 5-methylcytosine DNA modification during spermatogenesis. They find that open reading frames of evolutionarily young and transcriptionally active LINE-1 retrotransposons are enriched in 5
Externí odkaz:
https://doaj.org/article/404f4300a2c74fb1b5b1fc739c852701
Autor:
Maciej Grzybek, Krzysztof Flisikowski, Tom Giles, Marta Dyjak, Rafal Ploski, Piotr Gasperowicz, Richard D. Emes, Pawel Lisowski
Publikováno v:
Applied Sciences, Vol 13, Iss 8, p 4798 (2023)
Swine is a common model organism for biomedical research. Epigenetic reprogramming in somatic cell nuclear transfer (SCNT) embryos does not fully recapitulate the natural DNA demethylation events at fertilisation. This study aimed to conduct genome-w
Externí odkaz:
https://doaj.org/article/a0362d5c6b2c42e5a959660a0d5e559f
Autor:
Joby Cole, Adrienn Angyal, Richard D. Emes, Tim John Mitchell, Mark J. Dickman, David H. Dockrell
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Epigenetic modifications regulate gene expression in the host response to a diverse range of pathogens. The extent and consequences of epigenetic modification during macrophage responses to Streptococcus pneumoniae, and the role of pneumolysin, a key
Externí odkaz:
https://doaj.org/article/fbd48eadf6794e8ca4498eb2aac07aff