Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Richard D. Carpenter"'
Autor:
Mark J. Kurth, Kit S. Lam, Sally J. DeNardo, Felice C. Lightstone, Danielle M. Solano, Mirela Andrei, Edmond Y. Lau, Arutselvan Natarajan, Richard D. Carpenter
Supplementary Figures 1-4, Methods from Halogenated Benzimidazole Carboxamides Target Integrin α4β1 on T-Cell and B-Cell Lymphomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a73e1c289069f2692b21b1aaa5b624c
https://doi.org/10.1158/0008-5472.22383792
https://doi.org/10.1158/0008-5472.22383792
Data from Halogenated Benzimidazole Carboxamides Target Integrin α4β1 on T-Cell and B-Cell Lymphomas
Autor:
Mark J. Kurth, Kit S. Lam, Sally J. DeNardo, Felice C. Lightstone, Danielle M. Solano, Mirela Andrei, Edmond Y. Lau, Arutselvan Natarajan, Richard D. Carpenter
Integrin α4β1 is an attractive but poorly understood target for selective diagnosis and treatment of T-cell and B-cell lymphomas. This report focuses on the rapid microwave preparation, structure-activity relationships, and biological evaluation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::664072d35f8e6155e4f60d85bccb4ae2
https://doi.org/10.1158/0008-5472.c.6500661
https://doi.org/10.1158/0008-5472.c.6500661
Publikováno v:
Applied Radiation and Isotopes. 70:2720-2729
Establishing improved methods for the radiolabeling of peptides with fluorine-18 via solid-phase peptide synthesis (SPPS) is desirable for the efficient synthesis of peptide-based molecular imaging agents. This work focuses on the development of a st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::195bd0de7e48b749ef062a0cb75fbe58
https://doi.org/10.1016/j.apradiso.2012.08.003
https://doi.org/10.1016/j.apradiso.2012.08.003
Autor:
Alan S. Verkman, Richard D. Carpenter
Publikováno v:
European Journal of Organic Chemistry. 2011:1242-1248
Triazacryptand (TAC)-based fluorescent K + sensors have broad biomedical utility, yet their advancement has been hindered because of their challenging synthesis. Herein, an efficient synthesis is reported that delivers a didesmethyl triazacryptand (d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7dec348f35b94abb66f4af5b93df670
https://doi.org/10.1002/ejoc.201001450
https://doi.org/10.1002/ejoc.201001450
Autor:
Mirela Andrei, Mark J. Kurth, Felice C. Lightstone, Olulanu H. Aina, Richard D. Carpenter, Kit S. Lam, Edmond Y. Lau, Ruiwu Liu
Publikováno v:
Journal of Medicinal Chemistry. 52:14-19
Current cancer chemotherapeutic agents clinically deployed today are designed to be indiscriminately cytotoxic, however, achieving selective targeting of cancer malignancies would allow for improved diagnostic and chemotherapeutic tools. Integrin alp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f7742279badfd7ee45bfd2ccc10dbe
https://doi.org/10.1021/jm800313f
https://doi.org/10.1021/jm800313f
Publikováno v:
Angewandte Chemie. 120:6507-6510
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a8033ed85e8743a970b53d7df91ddf8
https://doi.org/10.1002/ange.200801811
https://doi.org/10.1002/ange.200801811
Publikováno v:
Angewandte Chemie International Edition. 47:6407-6410
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e56936fd9e699640969d55b5851c23a
https://doi.org/10.1002/anie.200801811
https://doi.org/10.1002/anie.200801811
Autor:
Mark J. Kurth, Jason B. Holden, Dan Willenbring, Kristin A. Milinkevich, James C. Fettinger, Dean J. Tantillo, Richard D. Carpenter, Patrick B. DeBerdt, Taewoo Min
Publikováno v:
Journal of Combinatorial Chemistry. 10:225-229
A library of novel, propeller-shaped dispirotriheterocyclic isoxazolinopiperidinochromanones is reported. Each rigid dispirotriheterocycle was prepared in five linear steps from commercially available tert-butyl 4-oxopiperidine-1-carboxylate and vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb52890d1d68902cfd59b791267a450
https://doi.org/10.1021/cc700173x
https://doi.org/10.1021/cc700173x
Publikováno v:
Journal of Combinatorial Chemistry. 8:907-914
Using carbodiimide reagents [1,3-diisopropylcarbodiimide or N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride (EDC)], we have developed a mild, generalized, one-pot method that delivers N-2-arylaminobenzimidazole esters from commercially a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d6b4fadfa98420b50128bf6a70b0b4
https://doi.org/10.1021/cc060106b
https://doi.org/10.1021/cc060106b
Autor:
James C. Fettinger, Dino S. Tinti, Lori I. Robins, Makhluf J. Haddadin, Mark J. Kurth, Richard D. Carpenter
Publikováno v:
The Journal of Organic Chemistry. 71:2480-2485
1,2,4,5-Tetrazines (prepared from aryl nitriles) condense with isoxazolylcyclobutanones (prepared from 3-benzenesulfonyl-3-vinylcyclobutanol) in methanolic KOH to give conformationally restricted 6-isoxazol-5-yl-6,7-dihydro-5H-[1,2]diazocin-4-ones. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db218a67f6827af31f573404c96135b7
https://doi.org/10.1021/jo052577a
https://doi.org/10.1021/jo052577a