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of 6
pro vyhledávání: '"Richard D W Kelly"'
Autor:
L Gabriel Sanchez-Partida, Richard D W Kelly, Huseyin Sumer, Camden Y Lo, Rotem Aharon, Michael K Holland, Moira K O'Bryan, Justin C St John
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21597 (2011)
Oocyte cryopreservation is extremely beneficial for assisted reproductive technologies, the treatment of infertility and biotechnology and offers a viable alternative to embryo freezing and ovarian grafting approaches for the generation of embryonic
Externí odkaz:
https://doaj.org/article/2eb12464c9fd4091865299154903cc33
Autor:
Ann Liza Piberger, Akhil Bowry, Richard D. W. Kelly, Alexandra K. Walker, Daniel González-Acosta, Laura J. Bailey, Aidan J. Doherty, Juan Méndez, Joanna R. Morris, Helen E. Bryant, Eva Petermann
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Bulky DNA adducts are important replication-blocking lesions. Here the authors reveal that homologous recombination at bulky adducts in mammalian cells involves post-replicative gap repair in a PrimPol dependent manner.
Externí odkaz:
https://doaj.org/article/0f6811ec82d941be9a6362cf200f312d
Publikováno v:
Trends in cancer. 7(9)
Replication stress results from obstacles to replication fork progression, including ongoing transcription, which can cause transcription–replication conflicts. Oncogenic signaling can promote global increases in transcription activity, also termed
Autor:
William, Lee, Richard D W, Kelly, Ka Yu, Yeung, Gael, Cagnone, Matthew, McKenzie, Justin C, St John
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1330
The mitochondrial genome has a major role to play in establishing and maintaining pluripotency. Furthermore, mitochondrial DNA (mtDNA) copy is strictly regulated during differentiation. Undifferentiated, pluripotent cells possess fewer than 300 copie
Autor:
Richard D. W. Kelly, Shaun M. Cowley
Publikováno v:
Biochemical Society transactions. 41(3)
HDACs (histone deacetylases) 1 and 2 are ubiquitous long-lived proteins, which are often found together in three major multiprotein co-repressor complexes: Sin3, NuRD (nucleosome remodelling and deacetylation) and CoREST (co-repressor for element-1-s
Publikováno v:
Reproduction, Fertility & Development; Jun2010, Vol. 22 Issue 6, p956-965, 10p