Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Richard D Grieve"'
Autor:
Paul R Mouncey, Alvin Richards-Belle, Karen Thomas, David A Harrison, M Zia Sadique, Richard D Grieve, Julie Camsooksai, Robert Darnell, Anthony C Gordon, Doreen Henry, Nicholas Hudson, Alexina J Mason, Michelle Saull, Chris Whitman, J Duncan Young, François Lamontagne, Kathryn M Rowan, the 65 trial investigators
Publikováno v:
Health Technology Assessment, Vol 25, Iss 14 (2021)
Background: Vasopressors are administered to critical care patients to avoid hypotension, which is associated with myocardial injury, kidney injury and death. However, they work by causing vasoconstriction, which may reduce blood flow and cause other
Externí odkaz:
https://doaj.org/article/7608f160200d4a5d990ce3ec840ec1a1
Autor:
Sheila E Harvey, Francesca Parrott, David A Harrison, M Zia Sadique, Richard D Grieve, Ruth R Canter, Blair KP McLennan, Jermaine CK Tan, Danielle E Bear, Ella Segaran, Richard Beale, Geoff Bellingan, Richard Leonard, Michael G Mythen, Kathryn M Rowan
Publikováno v:
Health Technology Assessment, Vol 20, Iss 28 (2016)
Background: Malnutrition is a common problem in critically ill patients in UK NHS critical care units. Early nutritional support is therefore recommended to address deficiencies in nutritional state and related disorders in metabolism. However, evide
Externí odkaz:
https://doaj.org/article/93b6335bc1734ac9977e3b66bcf42135
Autor:
Paul R Mouncey, Tiffany M Osborn, G Sarah Power, David A Harrison, M Zia Sadique, Richard D Grieve, Rahi Jahan, Jermaine CK Tan, Sheila E Harvey, Derek Bell, Julian F Bion, Timothy J Coats, Mervyn Singer, J Duncan Young, Kathryn M Rowan
Publikováno v:
Health Technology Assessment, Vol 19, Iss 97 (2015)
Background: Early goal-directed therapy (EGDT) is recommended in international guidance for the resuscitation of patients presenting with early septic shock. However, adoption has been limited and uncertainty remains over its clinical effectiveness a
Externí odkaz:
https://doaj.org/article/75ed5f801cba42b8a23a9d5c540a40a8
Autor:
Karen Thomas, Akshay Patel, M Zia Sadique, Richard D Grieve, Alexina J Mason, Silvia Moler, Anthony C Gordon, Kathryn M Rowan, Paul R Mouncey, Francois Lamontagne, David A Harrison
The 65 trial is a pragmatic, multicentre, parallel-group, open-label, randomised clinical trial of permissive hypotension (targeting a mean arterial pressure target of 60–65 mmHg during vasopressor therapy) versus usual care in critically ill patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1dee42098e52041cb9eae66a0b2ba0f
Publikováno v:
Health economics. 21(6)
In cost-effectiveness analyses (CEA) that use randomized controlled trials (RCTs), covariates of prognostic importance may be imbalanced and warrant adjustment. In CEA that use non-randomized studies (NRS), the selection on observables assumption mus
Autor:
Alexina J. Mason, Richard D. Grieve, Alvin Richards-Belle, Paul R. Mouncey, David A. Harrison, James R. Carpenter
Publikováno v:
BMC Medical Research Methodology, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Missing data are an inevitable challenge in Randomised Controlled Trials (RCTs), particularly those with Patient Reported Outcome Measures. Methodological guidance suggests that to avoid incorrect conclusions, studies should under
Externí odkaz:
https://doaj.org/article/9619989e72c24fa7af6bb9a2acd64f77