Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Richard D Emes"'
Autor:
Michael Sulak, Lindsey Fong, Katelyn Mika, Sravanthi Chigurupati, Lisa Yon, Nigel P Mongan, Richard D Emes, Vincent J Lynch
Publikováno v:
eLife, Vol 5 (2016)
Externí odkaz:
https://doaj.org/article/78925d7991e64e18989f99b44a11c0b2
Autor:
Azad A Sulaiman, Katarzyna Zolnierczyk, Ornampai Japa, Jonathan P Owen, Ben C Maddison, Richard D Emes, Jane E Hodgkinson, Kevin C Gough, Robin J Flynn
Publikováno v:
PLoS Pathogens, Vol 12, Iss 11, p e1005991 (2016)
The trematode Fasciola hepatica is responsible for chronic zoonotic infection globally. Despite causing a potent T-helper 2 response, it is believed that potent immunomodulation is responsible for rendering this host reactive non-protective host resp
Externí odkaz:
https://doaj.org/article/4346b89fd77c4086a6de70b0779a5c4f
Autor:
Rodhan Patke, Anna E. Harris, Corinne L. Woodcock, Rachel Thompson, Rute Santos, Amber Kumari, Cinzia Allegrucci, Nathan Archer, Lorraine J. Gudas, Brian D. Robinson, Jenny L. Persson, Rupert Fray, Jennie Jeyapalan, Catrin S. Rutland, Emad Rakha, Srinivasan Madhusudan, Richard D. Emes, Musalwa Muyangwa-Semenova, Mansour Alsaleem, Simone de Brot, William Green, Hari Ratan, Nigel P. Mongan, Jennifer Lothion-Roy
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 56, Iss , Pp 101032- (2024)
Prostate cancer (PCa) is the second most common cancer diagnosed in men. While radical prostatectomy and radiotherapy are often successful in treating localised disease, post-treatment recurrence is common. As the androgen receptor (AR) and androgen
Externí odkaz:
https://doaj.org/article/f224ca60609a48d0bd38942bd1a03543
Publikováno v:
Frontiers in Microbiology, Vol 7 (2016)
The Pragmatic Insertional Mutation Mapping (PIMMS) laboratory protocol was developed alongside various bioinformatics packages (Blanchard et al 2015) to enable detection of essential and conditionally essential genes in Streptococcus and related bact
Externí odkaz:
https://doaj.org/article/fdd14b0cef7b420fa6feb510af4e75d5
Autor:
Michael Sulak, Lindsey Fong, Katelyn Mika, Sravanthi Chigurupati, Lisa Yon, Nigel P Mongan, Richard D Emes, Vincent J Lynch
Publikováno v:
eLife, Vol 5 (2016)
A major constraint on the evolution of large body sizes in animals is an increased risk of developing cancer. There is no correlation, however, between body size and cancer risk. This lack of correlation is often referred to as 'Peto's Paradox'. Here
Externí odkaz:
https://doaj.org/article/0ea76f26690c479db6fedee436f63684
Publikováno v:
Frontiers in Genetics, Vol 6 (2016)
De novo assembly of a complete transcriptome without the need for a guiding reference genome is attractive, particularly where the cost and complexity of generating a eukaryote genome is prohibitive. The transcriptome should not however be seen as ju
Externí odkaz:
https://doaj.org/article/e5f46648c9174a85b31fa64c0353b9fa
Publikováno v:
Frontiers in Genetics, Vol 6 (2015)
The PIMMS (Pragmatic Insertional Mutation Mapping System) pipeline has been developed for simple conditionally essential genome discovery experiments in bacteria. Capable of using raw sequence data files alongside a FASTA sequence of the reference ge
Externí odkaz:
https://doaj.org/article/ed59485785b74345931471425f93cddd
Autor:
Mark O Kitchen, Richard T Bryan, Kim E Haworth, Richard D Emes, Christopher Luscombe, Lyndon Gommersall, K K Cheng, Maurice P Zeegers, Nicholas D James, Adam J Devall, Anthony A Fryer, William E Farrell
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137003 (2015)
Inappropriate DNA methylation is frequently associated with human tumour development, and in specific cases, is associated with clinical outcomes. Previous reports of DNA methylation in low/intermediate grade non-muscle invasive bladder cancer (NMIBC
Externí odkaz:
https://doaj.org/article/a3cf01557fcd480eb56ec7eac1474195
Publikováno v:
Frontiers in Genetics, Vol 5 (2014)
For vertebrate organisms where a reference genome is not available, de novo transcriptome assembly enables a cost effective insight into the identification of tissue specific or differentially expressed genes and variation of the coding part of the g
Externí odkaz:
https://doaj.org/article/a08895d032964f0b88b5dec64390dcf4
Autor:
Emeli M Nilsson, Hernan P Fainberg, Siew S Choong, Thomas C Giles, James Sells, Sean May, Fiona J Stansfield, William R Allen, Richard D Emes, Alison Mostyn, Nigel P Mongan, Lisa Yon
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91717 (2014)
Adipose tissue (AT) is a dynamic and flexible organ with regulatory roles in physiological functions including metabolism, reproduction and inflammation; secreted adipokines, including leptin, and fatty acids facilitate many of these roles. The Afric
Externí odkaz:
https://doaj.org/article/301d9161423f424a881a6e90acb1e4d4