Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Richard D Antrobus"'
Autor:
Richard D Antrobus, Patrick J Lillie, Tamara K Berthoud, Alexandra J Spencer, James E McLaren, Kristin Ladell, Teresa Lambe, Anita Milicic, David A Price, Adrian V S Hill, Sarah C Gilbert
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48322 (2012)
Current influenza vaccines have reduced immunogenicity and are of uncertain efficacy in older adults. We assessed the safety and immunogenicity of MVA-NP+M1, a viral-vectored influenza vaccine designed to boost memory T cell responses, in a group of
Externí odkaz:
https://doaj.org/article/5ae393bd353248b788b0220b71fe0d22
Autor:
Richard D Antrobus, Alan B. Rickinson, Paul Moss, Naeem Khan, Damien J. Montamat-Sicotte, Benjamin E. Willcox, Lee I. Garner, Andrew D. Hislop
Leukocyte immunoglobulin-like receptor-1 (LIR-1) is an inhibitory receptor that negatively regulates T cell effector functions after interaction with host class I major histocompatibility complex molecules and, additionally, binds to UL18, a human cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6334941cd0093368993a1249020cb226
https://doi.org/10.1086/429927
https://doi.org/10.1086/429927
Autor:
Richard D Antrobus, Tamara Berthoud, Teresa Lambe, Lynda Coughlan, Adrian V. S. Hill, Sarah C. Gilbert, Matthew D. J. Dicks
Publikováno v:
Molecular Therapy
Adenoviruses are potent vectors for inducing and boosting cellular immunity to encoded recombinant antigens. However, the widespread seroprevalence of neutralizing antibodies to common human adenovirus serotypes limits their use. Simian adenoviruses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d80fdcb40fca54df26545ff8349712f8
https://doi.org/10.1038/mt.2013.284
https://doi.org/10.1038/mt.2013.284
Autor:
Teresa Lambe, Simon Kerridge, Matthew D. Snape, Ly-Mee Yu, Hill Avs., Alexandra J. Spencer, Thompson Bav., Richard D Antrobus, Jeremy Chalk, C. Jones, Andrew J. Pollard, Caitlin E. Mullarkey, P de Whalley, Sarah C. Gilbert
Publikováno v:
Pediatric Infectious Disease Journal. 31:e86-e91
Background: During seasonal influenza epidemics, 5-15% of the population are affected with an illness having a nontrivial mortality, morbidity and economic burden. Inactivated influenza vaccines are routinely used to prevent influenza infection, prim
Autor:
Rachel Richardson, Loredana Siani, Antonella Folgori, Riccardo Cortese, Evan W. Newell, Joannah R. Fergusson, Fabiana Grazioli, Cinzia Traboni, Alfredo Nicosia, Mark M. Davis, Adrian V. S. Hill, Leo Swadling, Maria Luisa Esposito, Richard D Antrobus, Dan Hameiri Bowen, Stefania Capone, John Halliday, Virginia Ammendola, Eleanor Barnes, Christabel Kelly, Anthony Brown, Mariarosaria Del Sorbo, Stefano Colloca, Ayako Kurioka, Paul Klenerman
A protective vaccine against hepatitis C virus (HCV) remains an unmet clinical need. HCV infects millions of people worldwide and is a leading cause of liver cirrhosis and hepatocellular cancer. Animal challenge experiments, immunogenetics studies, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5630f96dad24f45d69729b6fdc5420ee
http://hdl.handle.net/11588/621565
http://hdl.handle.net/11588/621565
Autor:
Adrian V. S. Hill, Sarah C. Gilbert, Caitlin E. Mullarkey, Maria Zambon, Lynda Coughlan, Katja Hoschler, Richard D Antrobus, Tamara Berthoud
Publikováno v:
Molecular Therapy. 22(1)
Current seasonal influenza vaccines have reduced immunogenicity and are of suboptimal efficacy in older adults. We have previously shown that the novel candidate vaccine MVA-NP+M1 is able to boost memory T cell responses in adults aged 50-85 years. P
Autor:
Leo Swadling, Richard D Antrobus, Ayako Kurioka, Eleanor Barnes, C Willberg, M. Naddeo, Stefano Colloca, Maria Luisa Esposito, Virginia Ammendola, Antonella Folgori, Kira Smith, Stephen Aston, Joel Meyer, Geraldine O'Hara, Loredana Siani, Fabiana Grazioli, Adrian V. S. Hill, Cinzia Traboni, Paul Klenerman, Stefania Capone, Anthony Brown, Alfredo Nicosia, Riccardo Cortese, Ye Oo, Abby Harrison, Rachel Townsend, Rachel Huddart, David H. Adams
Currently, no vaccine exists for hepatitis C virus (HCV), a major pathogen thought to infect 170 million people globally. Many studies suggest that host T cell responses are critical for spontaneous resolution of disease, and preclinical studies have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::850fe882181402715e216e45f834e670
http://hdl.handle.net/11588/428786
http://hdl.handle.net/11588/428786