Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Richard D, Irons"'
Autor:
Richard D. Irons, Patrick J. Kerzic
Publikováno v:
Environmental toxicology and pharmacology. 55
Results of laboratory studies and investigations of occupationally exposed healthy individuals have been used to develop a mode of action for benzene-induced leukemia that mirrors disease following treatment with chemotherapeutic agents. Recently we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f2e16c269300ae706a5ddde52b42e21
https://pubmed.ncbi.nlm.nih.gov/28926803
https://pubmed.ncbi.nlm.nih.gov/28926803
Publikováno v:
Occupational and Environmental Medicine. 71:266-274
Background Benzene exposure has been associated with increased risk of leukaemia and myelodysplastic syndrome. Existing studies are sparse for other lymphohaematopoietic cancer subtypes, such as myeloproliferative disease (MPD) and the related chroni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1cbdd9d2df560adb86f0ff6786a7e7
https://doi.org/10.1136/oemed-2013-101664
https://doi.org/10.1136/oemed-2013-101664
Publikováno v:
Genes, Chromosomes and Cancer. 52:887-894
Benzene (Bz) is widely regarded as a prototype environmental leukemogen and individuals chronically exposed are at risk for myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). It is widely assumed that initiation and pathogenesis of AML
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf1840b4219461af30dd8053e26ac894
https://doi.org/10.1002/gcc.22084
https://doi.org/10.1002/gcc.22084
Publikováno v:
American Journal of Clinical Pathology. 133:305-313
In diffuse large B-cell lymphoma (DLBCL), BCL2 expression usually correlates with the t(14;18) (q32;q21) in germinal center B-cell (GCB) subtype and with gain/amplification of chromosome 18q21 in the activated B cell–like subtype. Studies have sugg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::673bcb77be07e133ec476996c7e61ab9
https://doi.org/10.1309/ajcp4h6adgydzmoa
https://doi.org/10.1309/ajcp4h6adgydzmoa
Autor:
Xiaoqin Wang, Anh T. Le, Yan Chen, Richard D. Irons, Xiongzeng Zhu, Meirong Ji, Liming Bao, Guowei Lin, Xichun Wu, John Ryder
Publikováno v:
Leukemia Research. 33:1599-1603
The clinical, cytogenetic and molecular features of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), a disease previously considered to be rare in Asia, were examined in consecutive series of 70 cases diagnosed by our laboratory ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ebef47c9eb01ba28451da85b40e9c47
https://doi.org/10.1016/j.leukres.2008.12.021
https://doi.org/10.1016/j.leukres.2008.12.021
Autor:
Stephen M. Bowes, Liping Nie, Hongzhi Xu, Thomas W. Armstrong, Laiming Wang, Yimei Zhou, Hua Fu, Richard D. Irons, Otto Wong, Hong Liu, Jinbin Fang, Youxin Liang, A R Schnatter
Publikováno v:
Journal of Occupational and Environmental Hygiene. 6:659-670
A systematic review of the Chinese literature was conducted from 1956 to 2005. The survey included both online and manual searching, as well as expert discussions aimed at providing insight into factors affecting benzene exposure levels in paint/coat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dc5423082e803ac215dd58e6254c42c
https://doi.org/10.1080/15459620903249646
https://doi.org/10.1080/15459620903249646
Publikováno v:
International Journal of Hematology. 90:361-369
We characterized the prevalence, clinical and cytogenetic characteristics and survival of 435 patients diagnosed with de novo MDS in a single laboratory according to WHO criteria, and compared the utility of different scoring systems to predict survi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fc8b1bba9257ea110ab2155e3df069c
https://doi.org/10.1007/s12185-009-0403-5
https://doi.org/10.1007/s12185-009-0403-5
Autor:
J J Gruntmeir, Sherilyn A. Gross, Wayne S. Stillman, Karen M. Helm, Richard D. Irons, David W. Pyatt
Publikováno v:
European Journal of Haematology. 59:318-326
Our current understanding of human haematopoietic stem cell biology is based in part on the characterization of human CD34+ bone marrow cell differentiation in vitro. CD34 is highly expressed on early stem cells and haematopoietic progenitor cells wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2146f2a5a4b4a968bb46adc3211fb989
https://doi.org/10.1111/j.1600-0609.1997.tb01693.x
https://doi.org/10.1111/j.1600-0609.1997.tb01693.x
Autor:
Richard D. Irons, Wayne S. Stillman
Publikováno v:
European Journal of Haematology. 57:119-124
A characteristic shared by a diverse group of myelotoxic compounds and leukaemogens is the ability to act synergistically with granulocyte–macrophage colony stimulating factor (GM-CSF) in increasing clonogenic response. Pretreatment of murine or hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf0c0c28de4b0f3c221439bc060d816
https://doi.org/10.1111/j.1600-0609.1996.tb01657.x
https://doi.org/10.1111/j.1600-0609.1996.tb01657.x
Autor:
Richard D. Irons, Anh T. Le
Publikováno v:
Chemico-Biological Interactions. 172:81-92
Epstein-Barr virus (EBV) is implicated in the development of a number of human malignancies including several subtypes of non-Hodgkin lymphoma (NHL) [G. Pallesen, S.J. Hamilton-Dutoit, X. Zhou, The association of Epstein-Barr virus (EBV) with T cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f375573e33d36d8ec930fadc241be3
https://doi.org/10.1016/j.cbi.2007.11.005
https://doi.org/10.1016/j.cbi.2007.11.005