Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Richard Cumming"'
Autor:
Edward Hawkins, Richard Cumming
Publikováno v:
Journal of Histochemistry & Cytochemistry. 38:415-419
The ability to use enhanced chemiluminescence (ECL) to detect horseradish peroxidase as a label for tissue antigens and cellular viral DNA was demonstrated. A liquid nitrogen-cooled charged-coupled device (CCD) was used to detect light output, which
Autor:
Jonathan Wilson, Lei Cui, Costa Salojin, Anna Gardberg, Valerie Vivat, Jeffrey Lauer, Nico Cantone, Jacob Stuckey, Florence Poy, Ingrid Almeciga, Richard Cummings, Julian Levell, Jennifer Rocnik, Patrick Trojer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/2a8dd470c8804d72acb6de09b7967109
Autor:
Anna S. Gardberg, Annissa J. Huhn, Richard Cummings, Archana Bommi-Reddy, Florence Poy, Jeremy Setser, Valerie Vivat, Francois Brucelle, Jonathan Wilson
Publikováno v:
Structural Dynamics, Vol 6, Iss 5, Pp 054702-054702-5 (2019)
Histone acetyltransferases (HATs) and histone deacetylases (HDACs) catalyze the dynamic and reversible acetylation of proteins, an epigenetic regulatory mechanism associated with multiple cancers. Indeed, HDAC inhibitors are already approved in the c
Externí odkaz:
https://doaj.org/article/00d4b497da21451cbeb22fa2b55cf9b5
Autor:
Robert D. Burgoyne, Richard Cumming
Publikováno v:
Bioscience Reports. 3:997-1006
Introduction The neuronal cytoskeJeton controls a myriad of functions in the adult and developing central nervous system including cell division, growth, motility, cellular shape, axonal and dendritic transport, neurosecretion, etc (1). The assembled
Publikováno v:
Neuroscience Letters. 27:313-318
This study describes the ultastructural localization of the opioid peptide enkephalin (ENK) in the preoptic nucleus of the goldfish. Using immunocytochemical techniques, ENK could be seen in neurosecretory granules and throughout the cytoplasm of mag
Autor:
Robert D. Burgoyne, Richard Cumming
Publikováno v:
FEBS Letters. 146:273-277
Calcium-dependent proteolysis of several polypeptides from rat brain and synaptosomal cytosol was observed including proteolysis of polypeptides of Mr 340 000 and 300 000. These latter polypeptides comigrated with high-Mr microtubule-associated prote
Publikováno v:
Neuroscience. 12:775-782
In vivo developmental immunocytochemical studies have recently shown that granule cell axons (parallel fibres) undergo progressive modification of alpha tubulin as they form permanent synapses, a change that is not observed in other microtubule-conta
Autor:
Richard Cumming, Robert D. Burgoyne
Publikováno v:
Brain Research. 280:190-193
Synaptosomes assemble an equatorial coil of microtubules during incubation at 37°C. Stimulation of synaptosomes by veratridine or A23187 for 5 min results in disassembly of the microtubules. The role of microtubule disassembly in neurotransmitter re
Publikováno v:
Proceedings of the Royal Society of London. Series B. Biological Sciences. 216:385-396
When synaptosomes are prepared from rat brain and incubated in Krebs solution, the presynaptic bulb develops a coil of microtubules (mts). Various considerations indicate that the coil does not have a cytoskeletal supportive function. Synaptosome coi
Publikováno v:
Neuroscience Letters. 22:119-124
An immunofluorescent technique has demonstrated that tissue-bound pools of cyclic GMP, calmodulin and cyclic GMP-dependent protein kinase are localized within the cytoplasm of the epithelial cells of the choroid plexus. In all other cell types and re