Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Richard Coffee"'
Autor:
Jae-Beom Kim, Konnie Urban, Edward Cochran, Steve Lee, Angel Ang, Bradley Rice, Adam Bata, Kenneth Campbell, Richard Coffee, Alex Gorodinsky, Zhan Lu, He Zhou, Takashi Kei Kishimoto, Peter Lassota
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9364 (2010)
Early detection of tumors can significantly improve the outcome of tumor treatment. One of the most frequently asked questions in cancer imaging is how many cells can be detected non-invasively in a live animal. Although many factors limit such detec
Externí odkaz:
https://doaj.org/article/aff5baf930c54d018af305b3ab814cfe
Autor:
Weiwu Jiang, Lihua Wang, Richard Coffee, Inayat S. Fazili, Bhagavatula Moorthy, Weisheng Zhang
Publikováno v:
Biochemical and Biophysical Research Communications. 390:1419-1424
There is significant human exposure to polycyclic aromatic hydrocarbons (PAHs), many of which are potent carcinogens. Cytochrome P450 (CYP)1A enzymes play key roles in the metabolic activation of PAHs to carcinogenic metabolites. We previously showed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc1e2f5a78c500c54d19b36ae30f28a
https://doi.org/10.1016/j.bbrc.2009.11.021
https://doi.org/10.1016/j.bbrc.2009.11.021
Autor:
Ed Lim, Tony Purchio, Anne C Clermont, John J. Hunter, Scott K. Lyons, Joan Dusich, Kenneth D. Campbell, Darlene Jenkins, Lingyun Zhu, Richard Coffee, David S. Grass
Publikováno v:
Cancer Research. 66:4701-4707
Several transgenic mouse models of prostate cancer have been developed recently that are able to recapitulate many key biological features of the human condition. It would, therefore, be desirable to employ these models to test the efficacy of new th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcd531a05bd53c32132cdaae478e8002
https://doi.org/10.1158/0008-5472.can-05-3598
https://doi.org/10.1158/0008-5472.can-05-3598
Autor:
Edward Cochran, Alex Gorodinsky, Zhan Lu, Kenneth D. Campbell, Peter Lassota, Steve R. Lee, Jae-Beom Kim, He Zhou, Konnie Urban, Takashi Kishimoto, Bradley W. Rice, Angel Ang, Adam Bata, Richard Coffee
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9364 (2010)
PLoS ONE
PLoS ONE
Early detection of tumors can significantly improve the outcome of tumor treatment. One of the most frequently asked questions in cancer imaging is how many cells can be detected non-invasively in a live animal. Although many factors limit such detec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0157c2622b1b278190c10475bff7e5c
http://europepmc.org/articles/PMC2826408?pdf=render
http://europepmc.org/articles/PMC2826408?pdf=render
Publikováno v:
Proceedings of the National Academy of Sciences. 89:10321-10325
Transgenic lines of mice were derived by using plasmid constructs containing DNA encoding an antibody heavy chain variable-diversity-joining region (VH-D-JH) and various amounts of 5' and 3' flanking DNA but lacking any repetitive isotype switch (S)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e5d5038457f59af19f05d0b9a388d6
https://doi.org/10.1073/pnas.89.21.10321
https://doi.org/10.1073/pnas.89.21.10321
Autor:
Richard Coffee, Suzanne Fish, Paul D. Soloway, Tim Manser, Howard Passmore, Malcolm L. Gefter
Publikováno v:
The Journal of Experimental Medicine
The immunodominant CD4 T cell epitope of the bacteriophage lambda cI repressor protein in several inbred mouse strains can be represented by a peptide encompassing amino acids 12-26. Here, we show that this peptide, and a variety of its sequence vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04659705813b12adcf164225686ae453
https://doi.org/10.1084/jem.174.4.847
https://doi.org/10.1084/jem.174.4.847
Autor:
Richard Coffee, David B. West, Bhagavatula Moorthy, Kathirvel Muthiah, Min Chen, Anthony F. Purchio, Weisheng Zhang
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 82(1)
Here we describe a transgenic mouse model [Crl:CD-1(ICR)BR-Tg(Cyp1a2-luc)Xen] using luciferase as a reporter for Cyp1a2 gene regulation. An 8.4-kilobase mouse Cyp1a2 promoter driving the firefly luciferase gene was microinjected into single-cell-stag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::476679d4fbb46e8a6173cfbf7e21299f
https://pubmed.ncbi.nlm.nih.gov/15329440
https://pubmed.ncbi.nlm.nih.gov/15329440
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 32(2)
Previously we described a transgenic mouse model [FVB/NTg(CYP3A4-luc)Xen] using a reporter construct consisting of 13 kilobases of the human CYP3A4 promoter driving the firefly luciferase gene in the inbred FVB/N mouse strain. Here we report regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22436fd52c6635b3b01d53bd5974bc06
https://pubmed.ncbi.nlm.nih.gov/14744936
https://pubmed.ncbi.nlm.nih.gov/14744936
Autor:
Weisheng, Zhang, F, Purchio Anthony, Kevin, Chen, Jianming, Wu, Li, Lu, Richard, Coffee, R, Contag Pamela, B, West David
Publikováno v:
Drug Metabolism and Disposition; August 2003, Vol. 31 Issue: 8 p1054-64, 11p