Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Richard Chaillet"'
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9789811956416
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbe29d6da63688e209a49a5d0eccd952
https://doi.org/10.1007/978-981-19-5642-3_4
https://doi.org/10.1007/978-981-19-5642-3_4
Publikováno v:
Advances in experimental medicine and biology. 1396
Congenital heart disease (CHD) has a strong genetic etiology, making it a likely candidate for therapeutic intervention using genetic editing. Complex genetics involving an orchestrated series of genetic events and over 400 genes are responsible for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf25617f5bb4addb488b6ffa65ec1a3a
https://pubmed.ncbi.nlm.nih.gov/36454459
https://pubmed.ncbi.nlm.nih.gov/36454459
Autor:
J. Richard Chaillet
Publikováno v:
Transgenic Animals ISBN: 9781003211099
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47c08da317294fff9331bd733a674f6a
https://doi.org/10.1201/9781003211099-50
https://doi.org/10.1201/9781003211099-50
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135202 (2015)
Mutations in imprinted genes or their imprint control regions (ICRs) produce changes in imprinted gene expression and distinct abnormalities in placental structure, indicating the importance of genomic imprinting to placental development. We have rec
Externí odkaz:
https://doaj.org/article/b977e0b175c74bb081213a2953d9c219
Autor:
Serge McGraw, Christopher C Oakes, Josée Martel, M Cecilia Cirio, Pauline de Zeeuw, Winifred Mak, Christoph Plass, Marisa S Bartolomei, J Richard Chaillet, Jacquetta M Trasler
Publikováno v:
PLoS Genetics, Vol 9, Iss 11, p e1003873 (2013)
The maintenance of key germline derived DNA methylation patterns during preimplantation development depends on stores of DNA cytosine methyltransferase-1o (DNMT1o) provided by the oocyte. Dnmt1o(mat-/-) mouse embryos born to Dnmt1(Δ1o/Δ1o) female m
Externí odkaz:
https://doaj.org/article/fcd229fc7143439d9c7283774ba18045
Autor:
Leonardo D'Aiuto, Marco Marzulli, K Naga Mohan, Ewa Borowczyk, Federica Saporiti, Andrew Vandemark, J Richard Chaillet
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9831 (2010)
Deletion analysis of mouse DNMT1, the primary maintenance methyltransferase in mammals, showed that most of the N-terminal regulatory domain (amino acid residues 412-1112) is required for its enzymatic activity. Although analysis of deletion mutants
Externí odkaz:
https://doaj.org/article/b880c0e449d04591b6ef2ad16edb8250
Autor:
Erik A. Koppes, Elena Sadovsky, Katherine P. Himes, J. Richard Chaillet, Yoel Sadovsky, Ben Shaffer, Yaacov Barak
Publikováno v:
Placenta
Introduction Imprinted genes are preferentially expressed from one parentally inherited allele, and many are crucial to the regulation of placental function and fetal growth. Murine Kruppel-like factor 14 (Klf14) is a maternally expressed imprinted t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd89e73a08fbd13c45ad67c3fb5d644
https://pubmed.ncbi.nlm.nih.gov/31675530
https://pubmed.ncbi.nlm.nih.gov/31675530
Autor:
Yaacov Barak, J. Richard Chaillet, Suyeon Kim, Calvin Simerly, Benjamin Shaffer, Sung Eun Lee, Srinivas Reddy Pallerla
Publikováno v:
genesis. 54:53-61
Among transgenic mice with ubiquitous Cre recombinase activity, all strains to date excise loxP-flanked (floxed) alleles either at or before the zygote stage or at nondescript stages of development. This manuscript describes a new mouse strain, in wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aab6ea0a3da1cf03cb25b7ba83a354f
https://doi.org/10.1002/dvg.22912
https://doi.org/10.1002/dvg.22912
Autor:
K. Naga Mohan, Isabella Soreca, Crescenzio Francesco Minervini, Leonardo D'Aiuto, Federica Saporiti, J. Timothy Greenamyre, J. Richard Chaillet, Roberto Di Maio
Publikováno v:
Differentiation. 82:9-17
High levels of DNA methyltransferase 1 (DNMT1), hypermethylation, and downregulation of GAD(67) and reelin have been described in GABAergic interneurons of patients with schizophrenia (SZ) and bipolar (BP) disorders. However, overexpression of DNMT1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab647c1f53e564505d741df0df7d1d8
https://doi.org/10.1016/j.diff.2011.03.003
https://doi.org/10.1016/j.diff.2011.03.003
Publikováno v:
Molecular and Cellular Biology. 31:1861-1869
DMAP1 (DNMT1-associated protein 1) is a member of the TIP60-p400 complex that maintains embryonic stem (ES) cell pluripotency and a complex containing the somatic form of DNA methyltransferase 1 (DNMT1s). DMAP1 interacts with DNMT1s through a domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80374e08dd599b1aeaa6bf963c4c0e14
https://doi.org/10.1128/mcb.01390-10
https://doi.org/10.1128/mcb.01390-10