Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Richard Chahwan"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Melanomas are highly immunogenic tumors that have been shown to activate the immune response. Nonetheless, a significant portion of melanoma cases are either unresponsive to immunotherapy or relapsed due to acquired resistance. During melanomagenesis
Externí odkaz:
https://doaj.org/article/2ab0d6599a1544968146e51f96591601
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The tumor microenvironment and its contribution to tumorigenesis has been a focal highlight in recent years. A two-way communication between the tumor and the surrounding microenvironment sustains and contributes to the growth and metastasis
Externí odkaz:
https://doaj.org/article/36ece03acd144a9ebeca7096df202b04
Publikováno v:
Journal of Extracellular Biology, Vol 1, Iss 4, Pp n/a-n/a (2022)
Abstract Coronavirus disease 2019 (COVID‐19) has transformed very quickly into a world pandemic with severe and unexpected consequences on human health. Concerted efforts to generate better diagnostic and prognostic tools have been ongoing. Researc
Externí odkaz:
https://doaj.org/article/15d4d427613f425e86f061c88f737296
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
The wealth of high-throughput data has opened up new opportunities to analyze and describe biological processes at higher resolution, ultimately leading to a significant acceleration of scientific output using high-throughput data from the different
Externí odkaz:
https://doaj.org/article/577c2287e2214c148e48f529555e3868
Publikováno v:
Bio-Protocol, Vol 11, Iss 21 (2021)
DNA and RNA nucleases are wide-ranging enzymes, taking part in broad cellular processes from DNA repair to immune response control. Growing interest in the mechanisms and activities of newly discovered nucleases inspired us to share the detailed prot
Externí odkaz:
https://doaj.org/article/739ec4e26c6f402da0682676c237239c
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/4d93fd40fd0c4edbbd601446f43b2bb0
Autor:
Rikke Morrish, Kevin Ho Wai Yim, Stefano Pagliara, Francesca Palombo, Richard Chahwan, Nicholas Stone
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Large-scale intracellular signaling during developmental growth or in response to environmental alterations are largely orchestrated by chromatin within the cell nuclei. Chemical and conformational modifications of the chromatin architecture are crit
Externí odkaz:
https://doaj.org/article/ee87541208834605b507348297cf643c
Autor:
Rikke Brandstrup Morrish, Michael Hermes, Jeremy Metz, Nicholas Stone, Stefano Pagliara, Richard Chahwan, Francesca Palombo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
The dynamic architecture of chromatin, the macromolecular complex comprised primarily of DNA and histones, is vital for eukaryotic cell growth. Chemical and conformational changes to chromatin are important markers of functional and developmental pro
Externí odkaz:
https://doaj.org/article/41eca15b4b504a02b19105d2b6ece3ea
Autor:
Emily C. Sheppard, Rikke Brandstrup Morrish, Michael J. Dillon, Rebecca Leyland, Richard Chahwan
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Epigenetic modifications, such as histone modifications, DNA methylation status, and non-coding RNAs (ncRNA), all contribute to antibody maturation during somatic hypermutation (SHM) and class-switch recombination (CSR). Histone modifications alter t
Externí odkaz:
https://doaj.org/article/abe6d84d96a94abeb76b61585d83da01
