Functional Characterization and Direct Comparison of Influenza A, B, C, and D NS1 Proteins in vitro and in vivo

Autor: Aitor Nogales, Teresa Aydillo, Gines Ávila-Pérez, Alba Escalera, Kevin Chiem, Richard Cadagan, Marta L. DeDiego, Feng Li, Adolfo García-Sastre, Luis Martínez-Sobrido

Publikováno v: Frontiers in Microbiology, Vol 10 (2019)

Influenza viruses are important pathogens that affect multiple animal species, including humans. There are four types of influenza viruses: A, B, C, and D (IAV, IBV, ICV, and IDV, respectively). IAV and IBV are currently circulating in humans and are

Externí odkaz: https://doaj.org/article/976372a4446346e29c8e158b61ffd5bc

Dengue Virus Immunity Increases Zika Virus-Induced Damage during Pregnancy

Autor: Justin J. Frere, Adam Jacobs, Richard Cadagan, Jean K. Lim, Julia A. Brown, Gregory A. Foster, Florian Krammer, Silviana Lee, Gursewak Singh, Kevin W. Hoffman, James Duehr, Anupa Chokola, David E. Krysztof, Susan L. Stramer, Joshua A. Acklin, Adolfo García-Sastre

Publikováno v: Immunity. 50:751-762.e5

Zika virus (ZIKV) has recently been associated with birth defects and pregnancy loss after maternal infection. Because dengue virus (DENV) and ZIKV co-circulate, understanding the role of antibody-dependent enhancement in the context of pregnancy is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c689461567595f18ad9a5b88e716d8
https://doi.org/10.1016/j.immuni.2019.01.005

Maternal influenza viral infection causes schizophrenia-like alterations of 5-HT₂A and mGlu₂ receptors in the adult offspring

Autor: José L, Moreno, Mitsumasa, Kurita, Terrell, Holloway, Javier, López, Richard, Cadagan, Luis, Martínez-Sobrido, Adolfo, García-Sastre, Javier, González-Maeso

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience. 31(5)

Epidemiological studies indicate that maternal influenza viral infection increases the risk for schizophrenia in the adult offspring. The serotonin and glutamate systems are suspected in the etiology of schizophrenia, as well as in the mechanism of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::00f012617b3f46d2e8ee198b2b14ff80
https://pubmed.ncbi.nlm.nih.gov/21289196

The immunological potency and therapeutic potential of a prototype dual vaccine against influenza and Alzheimer's disease

Autor: Irina Petrushina, Anahit Ghochikyan, Richard Cadagan, Hayk Davtyan, Dmitriy Zamarin, Michael G. Agadjanyan, Randy A. Albrecht, Adolfo García-Sastre, Nina Movsesyan, Luis Martinez-Sobrido

Publikováno v: Davtyan, Hayk; Ghochikyan, Anahit; Cadagan, Richard; Zamarin, Dmitriy; Petrushina, Irina; Movsesyan, Nina; et al.(2011). The immunological potency and therapeutic potential of a prototype dual vaccine against influenza and Alzheimer's disease. Journal of Translational Medicine, 9(1), 127. doi: 10.1186/1479-5876-9-127. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/73w674qg
Journal of Translational Medicine
Journal of Translational Medicine, Vol 9, Iss 1, p 127 (2011)
Davtyan, Hayk; Ghochikyan, Anahit; Cadagan, Richard; Zamarin, Dmitriy; Petrushina, Irina; Movsesyan, Nina; et al.(2011). The immunological potency and therapeutic potential of a prototype dual vaccine against influenza and Alzheimer's disease. Journal of Translational Medicine, 9(1), 127. doi: http://dx.doi.org/10.1186/1479-5876-9-127. Retrieved from: http://www.escholarship.org/uc/item/1k71117d

Background Numerous pre-clinical studies and clinical trials demonstrated that induction of antibodies to the β-amyloid peptide of 42 residues (Aβ42) elicits therapeutic effects in Alzheimer's disease (AD). However, an active vaccination strategy b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e754c65afbdd74ee3d7ab9b009be1973