Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Richard C. Winneker"'
Autor:
Russell R. Broaddus, Cheryl L. Walker, Richard C. Winneker, Judy S. Crabtree, Heather A. Harris, Adrienne S. McCampbell
Perspective on this Article from Loss of Inhibitory Insulin Receptor Substrate-1 Phosphorylation Is an Early Event in Mammalian Target of Rapamycin–Dependent Endometrial Hyperplasia and Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749233eb60b895463ca6e142fdb827ab
https://doi.org/10.1158/1940-6207.22524132.v1
https://doi.org/10.1158/1940-6207.22524132.v1
Autor:
Cheryl L. Walker, Richard C. Winneker, Magid Abou-Gharbia, Jerauld S. Skotnicki, Wenling Kao, Eugene L. Brown, Russell R. Broaddus, Bhuvanesh Dave, Adrienne S. McCampbell, Wei Liu, Kathryn A. Saraf, Ewa Wilson, Michelle L. Kimberland, Monette M. Cotreau, Sung E. Choe, Heather A. Harris, Scott A. Jelinsky, Judy S. Crabtree
Supplementary Table 1 from Comparison of Human and Rat Uterine Leiomyomata: Identification of a Dysregulated Mammalian Target of Rapamycin Pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ee0312576692d2359aa6868e077996
https://doi.org/10.1158/0008-5472.22378002
https://doi.org/10.1158/0008-5472.22378002
Autor:
Cheryl L. Walker, Richard C. Winneker, Magid Abou-Gharbia, Jerauld S. Skotnicki, Wenling Kao, Eugene L. Brown, Russell R. Broaddus, Bhuvanesh Dave, Adrienne S. McCampbell, Wei Liu, Kathryn A. Saraf, Ewa Wilson, Michelle L. Kimberland, Monette M. Cotreau, Sung E. Choe, Heather A. Harris, Scott A. Jelinsky, Judy S. Crabtree
Supplementary Table 3 from Comparison of Human and Rat Uterine Leiomyomata: Identification of a Dysregulated Mammalian Target of Rapamycin Pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eeadc07c3d5cb2cba812ec3e00abad0
https://doi.org/10.1158/0008-5472.22377996.v1
https://doi.org/10.1158/0008-5472.22377996.v1
Autor:
Cheryl L. Walker, Richard C. Winneker, Magid Abou-Gharbia, Jerauld S. Skotnicki, Wenling Kao, Eugene L. Brown, Russell R. Broaddus, Bhuvanesh Dave, Adrienne S. McCampbell, Wei Liu, Kathryn A. Saraf, Ewa Wilson, Michelle L. Kimberland, Monette M. Cotreau, Sung E. Choe, Heather A. Harris, Scott A. Jelinsky, Judy S. Crabtree
Supplementary Methods from Comparison of Human and Rat Uterine Leiomyomata: Identification of a Dysregulated Mammalian Target of Rapamycin Pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::689bedcffbc5615d69e975e9371d9425
https://doi.org/10.1158/0008-5472.22378005.v1
https://doi.org/10.1158/0008-5472.22378005.v1
Autor:
Cheryl L. Walker, Richard C. Winneker, Magid Abou-Gharbia, Jerauld S. Skotnicki, Wenling Kao, Eugene L. Brown, Russell R. Broaddus, Bhuvanesh Dave, Adrienne S. McCampbell, Wei Liu, Kathryn A. Saraf, Ewa Wilson, Michelle L. Kimberland, Monette M. Cotreau, Sung E. Choe, Heather A. Harris, Scott A. Jelinsky, Judy S. Crabtree
Supplementary Table 2 from Comparison of Human and Rat Uterine Leiomyomata: Identification of a Dysregulated Mammalian Target of Rapamycin Pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::653d89c66861b9901cc0faf0967526fa
https://doi.org/10.1158/0008-5472.22377999
https://doi.org/10.1158/0008-5472.22377999
Autor:
Cheryl L. Walker, Richard C. Winneker, Magid Abou-Gharbia, Jerauld S. Skotnicki, Wenling Kao, Eugene L. Brown, Russell R. Broaddus, Bhuvanesh Dave, Adrienne S. McCampbell, Wei Liu, Kathryn A. Saraf, Ewa Wilson, Michelle L. Kimberland, Monette M. Cotreau, Sung E. Choe, Heather A. Harris, Scott A. Jelinsky, Judy S. Crabtree
Supplementary Table 4 from Comparison of Human and Rat Uterine Leiomyomata: Identification of a Dysregulated Mammalian Target of Rapamycin Pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b903ae166d34c4e3599343618f33d9a2
https://doi.org/10.1158/0008-5472.22377993.v1
https://doi.org/10.1158/0008-5472.22377993.v1
Autor:
John M. McCall, Jill Ann Panetta, Richard C. Winneker, Aaron D. Schimmer, Louis Degennaro, Kuldip D. Dave, Todd Sherer, Donald E. Frail, James Kasper, Alison Urkowitz
Publikováno v:
Drug Repositioning: Bringing New Life to Shelved Assets and Existing Drugs
Autor:
Paige Erin Mahaney, Elizabeth Koury, Thomas Kenney, Robert Emmett Mcdevitt, Richard C. Winneker, Gavin David Heffernan, Grace H. Johnston, Darlene C. Deecher, Eugene John Trybulski, Christine Huselton, Peter D. Alfinito, Jenifer A. Bray, Scott Cosmi, Albert J. Robichaud, Eric S. Manas, Yanfang Li, Coghlan Richard Dale
Publikováno v:
Bioorganic & Medicinal Chemistry. 17:7802-7815
The discovery of a series of 4-aminoethyl-3-(phenylsulfonyl)-1H-indoles, dual acting norepinephrine reuptake inhibitors (NRIs) and 5-HT2A receptor antagonists, is described. The synthesis and structure–activity relationship (SAR) of this novel seri
Autor:
Richard C. Winneker, Thomas J. Berrodin, Nilsa Graciani, Zhiming Zhang, Matthew R. Yudt, Sunil Nagpal, John A. Butera, Scott A. Jelinsky
Publikováno v:
Biochemical Pharmacology. 77:204-215
Progesterone receptor (PR) modulators are used in contraception and post-menopausal hormone therapy, and are under clinical development for reproductive disorders such as uterine fibroids and endometriosis. Development of tissue selective PR modulato
Autor:
Richard C. Winneker, Puwen Zhang, Terefenko Eugene Anthony, Zhiming Zhang, Andrew Fensome, Jeffrey I. Cohen, Ray Unwalla, Jay E. Wrobel, Matthew R. Yudt, Thomas J. Berrodin, Jeffrey Curtis Kern
Publikováno v:
Bioorganic & Medicinal Chemistry. 16:6589-6600
Novel 7-aryl benzo[1,4]oxazepin-2-ones were synthesized and evaluated as non-steroidal progesterone receptor (PR) modulators. The structure activity relationship of 7-aryl benzo[1,4]oxazepinones was examined using the T47D cell alkaline phosphatase a