Zobrazeno 1 - 10
of 330
pro vyhledávání: '"Richard C. Wilson"'
Autor:
Richard C. Wilson, Alaa Riezk, Paul Arkell, Damien Ming, Ryan Armiger, Victoria Latham, Mark J. Gilchrist, Anne-Grete Märtson, William W. Hope, Alison H. Holmes, Timothy M. Rawson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract In the face of increasing antimicrobial tolerance and resistance there is a global obligation to optimise oral antimicrobial dosing strategies including narrow spectrum penicillins, such as penicillin-V. We conducted a randomised, crossover
Externí odkaz:
https://doaj.org/article/97703b0946e84335a208e8fd496377c1
Autor:
Pau Herrero, Richard C. Wilson, Ryan Armiger, Jason A. Roberts, Alison Holmes, Pantelis Georgiou, Timothy M. Rawson
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Background and objective: Sub-therapeutic dosing of piperacillin-tazobactam in critically-ill patients is associated with poor clinical outcomes and may promote the emergence of drug-resistant infections. In this paper, an in silico investigation of
Externí odkaz:
https://doaj.org/article/c57dc60040a64d91a965876665f27fbb
Publikováno v:
Applied Network Science, Vol 3, Iss 1, Pp 1-15 (2018)
Abstract In a recent work we introduced a measure of importance for groups of vertices in a complex network. This centrality for groups is always between 0 and 1 and induces the eigenvector centrality over vertices. Furthermore, its value over any gr
Externí odkaz:
https://doaj.org/article/52920efd87be42fe999c8680dbd303d3
Publikováno v:
Entropy, Vol 20, Iss 10, p 759 (2018)
The problem of how to represent networks, and from this representation, derive succinct characterizations of network structure and in particular how this structure evolves with time, is of central importance in complex network analysis. This paper ta
Externí odkaz:
https://doaj.org/article/8867537876c5490e9b15e2b7399ec31b
Autor:
Alaa Riezk, Richard C. Wilson, Timothy M. Rawson, Vasin Vasikasin, Paul Arkel, Trevor J. Ferris, Lisa D. Haigh, Anthony E. G. Cass, Alison H. Holmes
Publikováno v:
Analytical Methods. 15:829-836
A LC/MS method for the simultaneous quantitative measurement of three beta-lactam antibiotics in serum and interstitial fluid samples.
Autor:
Alaa Riezk, Vasin Vasikasin, Richard C. Wilson, Timothy M. Rawson, James G. McLeod, Rishi Dhillon, Jamie Duckers, Anthony E. G. Cass, Alison H. Holmes
Publikováno v:
Analytical Methods. 15:746-751
LC/MS method for the simultaneous quantitative measurement of cefiderocol and meropenem in serum samples.
Autor:
Richard C Wilson, Paul Arkell, Alaa Riezk, Mark Gilchrist, Graham Wheeler, William Hope, Alison H Holmes, Timothy M Rawson
Publikováno v:
Journal of Antimicrobial Chemotherapy. 77:2364-2372
Objectives To explore the literature comparing the pharmacokinetic and clinical outcomes from adding probenecid to oral β-lactams. Methods Medline and EMBASE were searched from inception to December 2021 for all English language studies comparing th
Publikováno v:
IEEE Transactions on Geoscience and Remote Sensing. 60:1-13
Autor:
Timothy M Rawson, Richard C Wilson, Luke S P Moore, Alasdair P Macgowan, Andrew M Lovering, Mark Bayliss, Mathew Kyriakides, Mark Gilchrist, Jason A Roberts, William W Hope, Alison H Holmes
Publikováno v:
Open Forum Infectious Diseases
This healthy volunteer study aimed to explore phenoxymethylpenicillin (penicillin-V) pharmacokinetics (PK) to support the planning of large dosing studies in adults. Volunteers were dosed with penicillin-V at steady state. Total and unbound penicilli
Publikováno v:
Pattern Recognition Letters. 134:135-144
In this paper, we investigate both undirected and directed network evolution using the Euler–Lagrange equation. We use the Euler–Lagrange equation to develop a variational principle based on the von Neumann entropy for time-varying network struct