Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Richard C. Wiggins"'
Autor:
Richard C. Wiggins
Publikováno v:
Neurochemical Research. 34:158-168
The biology of normal prion protein and the property of infectivity observed in abnormal folding conformations remain thinly characterized. However, enough is known to understand that prion proteins stretch traditional views of proteins in biological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d77866ab079d13452b85ff7d1dfb30
https://doi.org/10.1007/s11064-008-9741-6
https://doi.org/10.1007/s11064-008-9741-6
Publikováno v:
International Journal of Cancer. 112:738-746
Ethanol is a tumor promoter and may promote metastasis of breast cancer. However, the underlying cellular/molecular mechanisms remain unknown. Overexpression and high activity of matrix metalloproteinase-2 (MMP-2) are frequently associated with metas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6454012c7420eb5d9848230af8cc9211
https://doi.org/10.1002/ijc.20497
https://doi.org/10.1002/ijc.20497
Publikováno v:
Neurochemistry International. 38:9-15
High molecular weight (HMW) fragmentation of nuclear chromatin was studied in cultured rat oligodendrocytes (OL) exposed to hydrogen peroxide (H2O2). Intact genomic DNA was isolated by agarose embedding, and analyzed by field inversion gel electropho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2370859cbf33c51277936f169293d7a7
https://doi.org/10.1016/s0197-0186(00)00066-8
https://doi.org/10.1016/s0197-0186(00)00066-8
Publikováno v:
Journal of Neuroscience Research. 55:303-310
An in vitro model system of cultured oligodendrocytes was used to determine the susceptibility of these cells to oxidative stress induced by 15 min exposure to millimolar concentrations of hydrogen peroxide (H2O2). Following the exposure, the cells w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80052f6b6ac2037f1a2f2a8928517b66
https://doi.org/10.1002/(sici)1097-4547(19990201)55:3<303::aid-jnr5>3.0.co
https://doi.org/10.1002/(sici)1097-4547(19990201)55:3<303::aid-jnr5>3.0.co
Publikováno v:
Metabolic Brain Disease. 14:197-203
The applicability of antisense technology to suppress the expression of myelin associated glycoprotein (MAG) in cultured oligodendrocytes was evaluated. Differentiating oligodendrocyte precursor cells obtained by the shake-off method were exposed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6beeb058358d7ccc09575574aa0cbe4f
https://doi.org/10.1023/a:1020666826384
https://doi.org/10.1023/a:1020666826384
Publikováno v:
Journal of Neuroscience Research. 50:928-936
Myelin-associated glycoprotein (MAG) is emerging as an important molecule involved in the plasticity and regeneration of the central nervous system. In this study, the structure of MAG gene promoter was characterized in cultured rat oligodendrocyte l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f97feaa8f99f636acbbbed42f2c8d4d
https://doi.org/10.1002/(sici)1097-4547(19971215)50:6<928::aid-jnr3>3.0.co
https://doi.org/10.1002/(sici)1097-4547(19971215)50:6<928::aid-jnr3>3.0.co
Publikováno v:
Journal of Neuroscience Research. 47:626-635
The purpose of this study was to characterize the selenium requirement for the normal differentiation of oligodendrocyte lineage cells. In primary mixed glial cultures prepared from newborn rat brains, the overall growth of cultures, as seen from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b0238b45c62c56fbc42769fb492b43f
https://doi.org/10.1002/(sici)1097-4547(19970315)47:6<626::aid-jnr8>3.0.co
https://doi.org/10.1002/(sici)1097-4547(19970315)47:6<626::aid-jnr8>3.0.co
Publikováno v:
Metabolic Brain Disease. 9:391-399
Induction of angiogenesis is essential for the continued growth of solid tumors, and one critical component of tumor-induced angiogenesis involves the stimulation of microvascular cells to migrate into the growing mass. We have developed a convenient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::600dfb585dec2f1a7caa129b9c948650
https://doi.org/10.1007/bf02098885
https://doi.org/10.1007/bf02098885
Publikováno v:
Journal of Neuroscience Research. 37:683-690
The treatment of rat glioma C6 cells with 10μ isoproterenol (Ipt) for 4 days upregulated the expression of the myelin-associated glycoprotein (MAG) gene by approximately 55-fold over the control value. The constant presence of Ipt in the medium was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26808a932f75196a9ffbe9bd2dec660b
https://doi.org/10.1002/jnr.490370603
https://doi.org/10.1002/jnr.490370603
Publikováno v:
Journal of Neuroscience Research. 37:208-212
The effect of dexamethasone on the expression of proteolipid protein (PLP) and myelin-associated glycoprotein (MAG) genes was investigated in rat C6 glioma cells. The steady state level of the respective mRNAs was quantitated by Northern blot analysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dad06735146fb4979f287124566f413
https://doi.org/10.1002/jnr.490370206
https://doi.org/10.1002/jnr.490370206