Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Richard C. Walovitch"'
Autor:
Guenther Brueggenwerth, Richard C. Walovitch, Colin G Miller, Klaus Noever, Robert Ford, David L. Raunig, Annette Schmid, Ivalina Hristova, Michael O'Neal, Michael O’Connor
Publikováno v:
Therapeutic Innovation & Regulatory Science. 55:1122-1138
Though many clinical trials rely on medical image evaluations for primary or key secondary endpoints, the methods to monitor reader performance are all too often mired in the legacy use of adjudication rates. If misused, this simple metric can be mis
Autor:
Colin G Miller, Liz Kuney, Michael O’Connor, Richard C. Walovitch, Annette Schmid, Robert W. Ford, Josy Breuer, Robert Ford, Guenther Brueggenwerth, David L. Raunig
Publikováno v:
Therapeutic Innovation & Regulatory Science
The debate over human visual perception and how medical images should be interpreted have persisted since X-rays were the only imaging technique available. Concerns over rates of disagreement between expert image readers are associated with much of t
Autor:
David L, Raunig, Annette M, Schmid, Colin G, Miller, Richard C, Walovitch, Michael, O'Connor, Klaus, Noever, Ivalina, Hristova, Michael, O'Neal, Guenther, Brueggenwerth, Robert R, Ford
Publikováno v:
Therapeutic innovationregulatory science. 55(6)
Though many clinical trials rely on medical image evaluations for primary or key secondary endpoints, the methods to monitor reader performance are all too often mired in the legacy use of adjudication rates. If misused, this simple metric can be mis
Autor:
Richard C. Walovitch
Publikováno v:
Clinical Research and Regulatory Affairs. 30:33-37
The FDA has recently issued a draft Guidance Standard for Clinical Trial Imaging Endpoints, which focuses on how to perform registration trials with imaging as an end-point or using imaging to determine patient eligibility. Leading up to the release
Publikováno v:
Biomarkers in Medicine. 6:839-847
The current cost of developing a successful drug is typically over a billion dollars, with the registration trial(s) determining the success or failure of the entire development program. Often the primary endpoint of these trials is a subjective asse
Autor:
Asli Memisoglu, Janet Wittes, Ami E Iskandrian, Sanjiv Kaul, Thomas R Porter, Roxy Senior, Mark J Monaghan, James E Udelson, Richard C Walovitch, Michael H Picard
Publikováno v:
Circulation. 118
Introduction RAMP (Realtime Assessment of Myocardial Perfusion Imaging) 1 and 2 showed that coronary artery disease (CAD) diagnosis with perfusion stress echocardiography (PSE) and perflubutane polymer microspheres in chest pain patients is as accura
Publikováno v:
International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology. 17:77-83
Autor:
Muralidhar Beeram, David Tuck, Eric K. Rowinsky, Alain C. Mita, Richard C. Walovitch, Cecilia Simmons, Lionel D. Lewis, Anne J. Stone, Anthony J. Olszanski, Kathleen Mackay, Susan Hammond, Monica M. Mita, Raymond P. Perez
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 13(11)
Purpose: AI-850, paclitaxel in a novel polyoxyethylated castor oil-free hydrophobic microparticle delivery system, is being developed based on its favorable preclinical safety and antitumor activity profiles. The objectives of the study were to asses
Autor:
Karen Y. Ong, Richard C. Walovitch, Zoltan Tyeklar, Katarina Midelfort, Huillori S. Ouellet, Hironao Sajiki, Erin M. Buchanan, Paul J. Bernard, David J. Parmelee, Daniel M. Scott, Thomas J. McMurry, Randall B. Lauffer, Robert P. Dolan
Publikováno v:
Academic Radiology. 3:S356-S358