Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Richard C. Venema"'
Publikováno v:
Vascular Pharmacology. 81:61-68
Production of NO by the endothelial nitric oxide synthase (eNOS) has a major role in blood pressure control and suppression of atherosclerosis. In a previous study, we presented evidence implicating the Pin1 prolyl isomerase in negative modulation of
Autor:
Steven J.T. Jackson, Andrew J. Young, Laura L. Murphy, Keith W. Singletary, Richard C. Venema
Publikováno v:
Food and Chemical Toxicology. 60:431-438
Curcumin, a component of turmeric spice that imparts flavor and color to curry, is thought to possess anti-inflammatory and antioxidant properties in biological tissues. However, while such efficacies have been described in the context of carcinogene
Autor:
Andrew J. Young, Richard C. Venema, Steven J.T. Jackson, Laura L. Murphy, Keith W. Singletary
Phytonutrients have rapidly emerged as natural food chemicals possessing multifaceted biological actions that may support beneficial health outcomes. Among the vast array of phytonutrients currently being studied, sulforaphane, curcumin, quercetin, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ab259059b4d5dc0c92a59d0ec74a13
https://europepmc.org/articles/PMC4717522/
https://europepmc.org/articles/PMC4717522/
Autor:
Christina M. Torres, James D. Mintz, David W. Stepp, Ling Ruan, Feng Chen, Richard C. Venema, David J. Fulton, Jin Qian
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 31:392-398
Objective— The Pin1 prolyl isomerase acts in concert with proline-directed protein kinases to regulate function of protein substrates through isomerization of peptide bonds that link phosphoserine or phosphothreonine to proline. We sought to determ
Autor:
Anton A. Komar, Maria Hatzoglou, Martin D. Snider, Mithu Majumder, Vladimir V. Zeenko, Francesca Gaccioli, Ibrahim Yaman, Mark G. Caprara, Chuanping Wang, Richard C. Venema
Publikováno v:
Molecular and Cellular Biology. 29:2899-2912
The response to amino acid starvation involves the global decrease of protein synthesis and an increase in the translation of some mRNAs that contain an internal ribosome entry site (IRES). It was previously shown that translation of the mRNA for the
Publikováno v:
European Journal of Applied Physiology. 104:795-802
Exercise training results in dynamic changes in skeletal muscle blood flow and metabolism. Nitric oxide (NO) influences blood flow, oxidative stress, and glucose metabolism. Hsp90 interacts directly with nitric oxide synthases (NOS), increasing NOS a
Autor:
Dong Wang, Richard C. Venema, Sergey Y. Cheranov, Baolin Zhang, Manjula Karpurapu, Gadiparthi N. Rao
Publikováno v:
Blood. 111:5581-5591
To understand the molecular mechanisms underlying 14,15-epoxyeicosatrienoic acid (14,15-EET)–induced angiogenesis, here we have studied the role of signal transducer and activator of transcription-3 (STAT-3). 14,15-EET stimulated the tyrosine phosp
Autor:
Cynthia Harmon, Dean A. Wiseman, Jeffrey R. Fineman, Sanjiv Kumar, Neetu Sud, Stephen M. Black, Shruti Sharma, Richard C. Venema
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 293:L1444-L1453
Previously, we have shown that pulmonary arterial endothelial cells (PAECs) isolated from fetal lambs produce significant levels of nitric oxide (NO) but minimal superoxide upon stimulation, whereas PAECs isolated from 4-wk-old lambs produce signific
Autor:
Christiana Dimitropoulou, W. Cam Patterson, Shuibing Qian, Tian Xia, Richard C. Venema, David Fulton, John D. Catravas, Jingmin Zeng, Andreas Papapetropoulos, Galina Antonova, Connie Snead
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 293:H3080-H3087
The nitric oxide receptor soluble guanylyl cyclase (sGC) exists in multimeric protein complexes, including heat shock protein (HSP) 90 and endothelial nitric oxide synthase. Inhibition of HSP90 by geldanamycin causes proteasomal degradation of sGC pr
Autor:
Chunying Li, Richard C. Venema, Andreas Papapetropoulos, Sarika G. Sood, David J. Fulton, Ling Ruan
Publikováno v:
Vascular Pharmacology. 47:257-264
Endothelial nitric oxide synthase (eNOS) catalyzes the conversion of L-arginine to L-citrulline and nitric oxide (NO), an important modulator of vascular function. eNOS is regulated post-translationally through phosphorylation/dephosphorylation at a