Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Richard C. Storr"'
Autor:
Roderick W. Bates, Richard C. Storr, Steven J. Collier, Mohamed Husaini bin Abdul Rahman, Raghunath O. Ramabhadran
Publikováno v:
Tetrahedron. 74:1-5
Trapping of a pyrimidinone-derived o-quinodimethane with tetraphenylcyclopentadienone gives a mixture of the [4 + 2] and formal [4 + 4] adducts. Computational studies show that the latter arises by a sequence of [4 + 2] cycloaddition, homolysis, radi
Autor:
Paul M. O'Neill, Jill Davies, Stephen A. Ward, Stephen Hindley, B. Kevin Park, Natalie L. Searle, Richard C. Storr, Patrick G. Bray
Publikováno v:
Journal of Medicinal Chemistry. 45:1052-1063
The potent antimalarial activity of chloroquine against chloroquine-sensitive strains can be attributed, in part, to its high accumulation in the acidic environment of the heme-rich parasite food vacuole. A key component of this intraparasitic chloro
Autor:
Antonio M. d'A. Rocha Gonsalves, Teresa M. V. D. Pinho e Melo, Claudia S. J. Lopes, Richard C. Storr
Publikováno v:
Synthesis. 2002:605-608
The thermolysis of haloazidoalkenes and 2-halo-2H-azirines is described. 2-Benzoyl-2-halo-2H-azirine-3-carboxylates (2a and 2b) underwent ring expansion leading to the synthesis of new 4-haloisoxazoles in high yield. The same isoxazoles were also obt
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :1795-1806
The transient 1-azafulvenium methides 24, 26 and 28 generated by thermal extrusion of sulfur dioxide from pyrrolo[1,2-c][1,3]thiazole 2,2-dioxide 20 (R = Me), 22 and 23 undergo sigmatropic [1,8]H shifts and the 1-acyl derivatives 30 electrocyclise to
Publikováno v:
Tetrahedron. 56:10011-10021
The pyrrolo[1,2-c]thiazole generated by dehydration of dimethyl 5-methyl-1H,3H-pyrrolo[1,2-c]thiazole-6,7-dicarboxylate 2-oxide acts as a thiocarbonyl ylide in its cycloaddition to electron deficient alkenes but as an azomethine ylide with electron d
Autor:
Frank E. Mabbs, and B. Kevin Park, Richard C. Storr, Natalie L. Searle, Paul M. O'Neill, Laurence P. D. Bishop, Stephen A. Ward, J. L. Maggs
Publikováno v:
The Journal of Organic Chemistry. 65:1578-1582
Autor:
Gary H. Posner, Paul O´Neill, James L. Maggs, Richard C. Storr, Natalie L. Searle, Stephen A. Ward, B. Kevin Park, Kaylene J. Raynes
Publikováno v:
Tetrahedron Letters. 39:6065-6068
Ozonolysis of R-carvone and in situ trapping with primary alcohols ROH (R= Me, Et, Bu, Pent, Oct) produces hydroperoxy ketals (5a-e) as a 1:1 mixture of diastereomers. Cyclisation of these intermediates with catalytic sodium methoxide in methanol pro
Publikováno v:
Tetrahedron. 54:4615-4622
Several approaches to the synthesis of 5-fluoro-6-methoxy-8-nitroquinoline 5, the key intermediate required for the synthesis of 5-fluoroprimaquine, were investigated. In one approach, 5-chloro-6-methoxy-8-nitroquinoline was synthesised and treated w
Autor:
Laurence P. D. Bishop, Paul M. O'Neill, Richard C. Storr, Patrick G. Bray, Natalie L. Searle, B. Kevin Park, James L. Maggs, Stephen A. Ward
Publikováno v:
Tetrahedron Letters. 38:4263-4266
Arteflene 4 reacts with FeCl 2 .4H 2 O in acetonitrile or with hemin / N-acetylcysteine (heme Fe(II)) in acetonitrile to produce the diol 5 and the enone 6 . Treatment of arteflene with Zn AcOH , a model of NADH dehydrogenase, results in the formatio
Autor:
Richard C. Storr, Lindsay A. White
Publikováno v:
Tetrahedron. 52:3117-3134
3-Methoxycarbonyl-4-keto-2,5-dihydrothiophene is a convenient starting point for synthesis of a range of 3,4- and 2,3-quinoline and quinolone and coumarin fused dihydrothiophene dioxides. With the exception of the 2,3-quinoline derivatives these all