Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Richard C. Luders"'
Autor:
Richard C. Luders, Linda A. Brunner
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 568:487-493
An analytical method employing reversed-phase high-performance liquid chromatography is described for the determination of a potential anxiolytic agent in human plasma. This experimental drug candidate has potent and selective affinity for the centra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe54ac7b3dfd2d1d78b8d83a7a1d2785
https://doi.org/10.1016/0378-4347(91)80188-i
https://doi.org/10.1016/0378-4347(91)80188-i
Autor:
Linda A. Brunner, Richard C. Luders
Publikováno v:
Journal of chromatographic science. 29(7)
An automated method utilizing laboratory robotics has been developed for quantifying diclofenac sodium concentrations in human plasma. The robotic system aliquots the biological sample, adds the internal standard (CGP 4287), extracts the compounds fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b7dd4b130c3a9e726aac96d46d6bec
https://pubmed.ncbi.nlm.nih.gov/1869614
https://pubmed.ncbi.nlm.nih.gov/1869614
Publikováno v:
Analytical Letters. 19:2183-2196
A method for the simultaneous determination of CGS 10787B and its major, metabolite (CGS 12094) in plasma is described. The two compounds, and the internal standard (dichlorinated analog), are extracted from acidified plasma with ethyl acetate, taken
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a57520a5d9fd5416f455b39bb85b96e
https://doi.org/10.1080/00032718608080876
https://doi.org/10.1080/00032718608080876
Autor:
M. Beth Maggio-Cavaliere, Oscar Resnick, Carina Li, Hanspeter Egger, Richard C. Luders, Michael J. Gaito, M. Fred Bartlett, Alexander Soo, Chemiker Htl, Oren B. Gum
Publikováno v:
Clinical Pharmacology & Therapeutics. 21:721-730
Plasma and urine concentrations of 2-(3-chloro-4[3-pyrrolinyl]phenyl) propionic acid, pirprofen, a new nonsteroidal anti-inflammatory compound, are described for normal male volunteers receiving one or more doses of the drug. Orally administered pirp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b0d57f971a672b9403bf69e711e4490
https://doi.org/10.1002/cpt1977216721
https://doi.org/10.1002/cpt1977216721
Autor:
Richard C. Luders, Linda A. Brunner
Publikováno v:
Journal of Chromatographic Science. 25:192-197
An automated method is described for analyzing biological samples originating from CGS 10787B drug disposition studies. The method incorporates a laboratory robot to prepare plasma and urine samples and a high performance liquid chromatographic syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d402d66e313aecb28b7a166b0f868499
https://doi.org/10.1093/chromsci/25.5.192
https://doi.org/10.1093/chromsci/25.5.192
Publikováno v:
Journal of agricultural and food chemistry. 18(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5751bc41dc61c5ef3df11ae51f62da6
https://pubmed.ncbi.nlm.nih.gov/5483055
https://pubmed.ncbi.nlm.nih.gov/5483055
Autor:
Richard C. Luders, Dolly Chao
Publikováno v:
Journal of Pharmaceutical Sciences. 70:1370-1371
The extent of warfarin and tolbutamide binding to plasma proteins was determined with and without pirprofen by an ultrafiltration procedure employing 14 C‐labeled drugs. Results from in vitro studies at 37° showed that the degree of binding amount
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc03aec533143e4b3cdd8deab7b7d64
https://doi.org/10.1002/jps.2600701221
https://doi.org/10.1002/jps.2600701221