Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Richard C. Lavin"'
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 101971- (2023)
Summary: The extent to which a drug accumulates in Mycobacterium tuberculosis (Mtb) and its host cell can affect treatment efficacy. We describe protocols measuring drug accumulation in Mtb, macrophages, and Mtb-infected macrophages. The method lever
Externí odkaz:
https://doaj.org/article/0c7e55d9c5a2436c8042cb9121bdddcb
Autor:
Richard C Lavin, Shumin Tan
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3, p e1010459 (2022)
A hallmark of Mycobacterium tuberculosis (Mtb) infection is the marked heterogeneity that exists, spanning lesion type differences to microenvironment changes as infection progresses. A mechanistic understanding of how this heterogeneity affects Mtb
Externí odkaz:
https://doaj.org/article/e0fc9534d3374660b4c4a7082a9c99a2
Autor:
Shumin Tan, Richard C. Lavin
Publikováno v:
PLoS pathogens. 18(3)
A hallmark of Mycobacterium tuberculosis (Mtb) infection with critical impact on disease development and outcome is the marked heterogeneity that exists, spanning differences in lesion types to changes in microenvironment as the infection progresses1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::475a9968c8977901f3920364d00c2c51
https://pubmed.ncbi.nlm.nih.gov/35344572
https://pubmed.ncbi.nlm.nih.gov/35344572
Autor:
Shumin Tan, Richard C. Lavin, Yan Pan, Yong-Mo Ahn, Nathan J. MacGilvary, Calvin Johnson, Yuzo Kevorkian, J. Fraser Glickman, Matthew Sherwood, Matthew D. Zimmerman, Joel S. Freundlich, Kyle M. Kremiller, David Giacalone, Jimmy Patel, Riccardo Russo
Publikováno v:
PLoS Biology, Vol 19, Iss 7, p e3001355 (2021)
PLoS Biology
PLoS Biology
Sensing and response to environmental cues, such as pH and chloride (Cl−), is critical in enabling Mycobacterium tuberculosis (Mtb) colonization of its host. Utilizing a fluorescent reporter Mtb strain in a chemical screen, we have identified compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aad1b49e41d2484817dd4d3aaf62918
https://doaj.org/article/e8e92b4c6c2a4557821d17bd95672572
https://doaj.org/article/e8e92b4c6c2a4557821d17bd95672572
Autor:
Brintha P. Girinathan, Lynn Bry, Mario L. Arrieta-Ortiz, Richard C. Lavin, Abraham L. Sonenshein, Yan Luo, Rupa Immanuel, Georg K. Gerber, Narjol Gonzalez Escalona, Christopher K Cummins, Andrew B. Onderdonk, Bruno Dupuy, Marc W. Allard, Nicholas DiBenedetto, Jay N. Worley, Nitin S. Baliga, Maria Hoffmann, Mary L. Delaney, Johann Peltier
SummaryWe define multiple mechanisms by which commensals protect against or worsenClostridioides difficileinfection. Leveraging new systems-level models we show how metabolically distinct species ofClostridiamodulate the pathogen’s colonization, gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7b346bf34827421822aa5ecac982114
https://doi.org/10.1101/2020.01.04.894915
https://doi.org/10.1101/2020.01.04.894915
Autor:
Richard C Lavin, Calvin Johnson, Yong-Mo Ahn, Kyle M Kremiller, Matthew Sherwood, Jimmy S Patel, Yan Pan, Riccardo Russo, Nathan J MacGilvary, David Giacalone, Yuzo L Kevorkian, Matthew D Zimmerman, J Fraser Glickman, Joel S Freundlich, Shumin Tan
Publikováno v:
PLoS Biology, Vol 19, Iss 7, p e3001355 (2021)
Sensing and response to environmental cues, such as pH and chloride (Cl-), is critical in enabling Mycobacterium tuberculosis (Mtb) colonization of its host. Utilizing a fluorescent reporter Mtb strain in a chemical screen, we have identified compoun
Externí odkaz:
https://doaj.org/article/e8e92b4c6c2a4557821d17bd95672572
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