Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Richard C. Krolewski"'
Autor:
Kimberly C. Paul, Richard C. Krolewski, Edinson Lucumi Moreno, Jack Blank, Kristina M. Holton, Tim Ahfeldt, Melissa Furlong, Yu Yu, Myles Cockburn, Laura K. Thompson, Alexander Kreymerman, Elisabeth M. Ricci-Blair, Yu Jun Li, Heer B. Patel, Richard T. Lee, Jeff Bronstein, Lee L. Rubin, Vikram Khurana, Beate Ritz
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Parkinson’s disease (PD) is a complex neurodegenerative disease with etiology rooted in genetic vulnerability and environmental factors. Here we combine quantitative epidemiologic study of pesticide exposures and PD with toxicity screening
Externí odkaz:
https://doaj.org/article/47501552806549668543baa91639d880
Autor:
Kimberly C. Paul, Richard C. Krolewski, Edinson Lucumi Moreno, Jack Blank, Kristina M. Holton, Tim Ahfeldt, Melissa Furlong, Yu Yu, Myles Cockburn, Laura K. Thompson, Alexander Kreymerman, Elisabeth M. Ricci-Blair, Yu Jun Li, Heer B. Patel, Richard T. Lee, Jeff Bronstein, Lee L. Rubin, Vikram Khurana, Beate Ritz
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/55332d37209d4a6087ffa62922fabdae
Autor:
Alain Ndayisaba, Ariana T. Pitaro, Andrew S. Willett, Kristie A. Jones, Claudio Melo de Gusmao, Abby L. Olsen, Jisoo Kim, Eero Rissanen, Jared K. Woods, Sharan R. Srinivasan, Anna Nagy, Amanda Nagy, Merlyne Mesidor, Steven Cicero, Viharkumar Patel, Derek H. Oakley, Idil Tuncali, Katherine Taglieri-Noble, Emily C. Clark, Jordan Paulson, Richard C. Krolewski, Gary P. Ho, Albert Y. Hung, Anne-Marie Wills, Michael T. Hayes, Jason P. Macmore, Luigi Warren, Pamela G. Bower, Carol B. Langer, Lawrence R. Kellerman, Christopher W. Humphreys, Bonnie I. Glanz, Elodi J. Dielubanza, Matthew P. Frosch, Roy L. Freeman, Christopher H. Gibbons, Nadia Stefanova, Tanuja Chitnis, Howard L. Weiner, Clemens R. Scherzer, Sonja W. Scholz, Dana Vuzman, Laura M. Cox, Gregor Wenning, Jeremy D. Schmahmann, Anoopum S. Gupta, Peter Novak, Geoffrey S. Young, Mel B. Feany, Tarun Singhal, Vikram Khurana
Publikováno v:
The Cerebellum.
Autor:
Alain Ndayisaba, Ariana T. Pitaro, Andrew S. Willett, Kristie A. Jones, Claudio Melo de Gusmao, Abby L. Olsen, Jisoo Kim, Eero Rissanen, Jared K. Woods, Sharan R. Srinivasan, Anna Nagy, Amanda Nagy, Merlyne Mesidor, Steven Cicero, Viharkumar Patel, Derek H. Oakley, Idil Tuncali, Katherine Taglieri-Noble, Emily C. Clark, Jordan Paulson, Richard C. Krolewski, Gary P. Ho, Albert Y. Hung, Anne-Marie Wills, Michael T. Hayes, Jason P. Macmore, Luigi Warren, Pamela G. Bower, Carol B. Langer, Lawrence R. Kellerman, Christopher W. Humphreys, Bonnie I. Glanz, Elodi J. Dielubanza, Matthew P. Frosch, Roy L. Freeman, Christopher H. Gibbons, Nadia Stefanova, Tanuja Chitnis, Howard L. Weiner, Clemens R. Scherzer, Sonja W. Scholz, Dana Vuzman, Laura M. Cox, Gregor Wenning, Jeremy D. Schmahmann, Anoopum S. Gupta, Peter Novak, Geoffrey S. Young, Mel B. Feany, Tarun Singhal, Vikram Khurana
Publikováno v:
The Cerebellum.
Multiple system atrophy (MSA) is a fatal neurodegenerative disease of unknown etiology characterized by widespread aggregation of the protein alpha-synuclein in neurons and glia. Its orphan status, biological relationship to Parkinson’s disease (PD
Autor:
Brett K. Beaulieu-Jones, William Yuan, Bruno Leroy, Lee L. Rubin, Tanya Fischer, Nathan Palmer, Scott Lipnick, Catherine Coulouvrat, Karen J. Chandross, Caroline Cohen, Anne-Marie Wills, Richard C. Krolewski, Francesca Frau, Sylvie Bozzi, Isaac S. Kohane, Christine Veyrat-Follet, Dinesh Kumar, Meaghan Cogswell, S. Pablo Sardi
Publikováno v:
BMC Neurology, Vol 21, Iss 1, Pp 1-12 (2021)
BMC Neurology
BMC Neurology
Background Characterization of prediagnostic Parkinson’s Disease (PD) and early prediction of subsequent development are critical for preventive interventions, risk stratification and understanding of disease pathology. This study aims to character
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51737 (2012)
The embryonic olfactory epithelium (OE) generates only a very few olfactory sensory neurons when the basic helix-loop-helix transcription factor, ASCL1 (previously known as MASH1) is eliminated by gene mutation. We have closely examined the structure
Externí odkaz:
https://doaj.org/article/7978988152224aa4af32144e616b8e23
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Aging is the biggest risk factor for several neurodegenerative diseases. Parabiosis experiments have established that old mouse brains are improved by exposure to young mouse blood. Previously, our lab showed that delivery of Growth Differentiation F
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
The family of olfactory receptors (ORs) subserves the sense of smell and includes both functional alleles and pseudogenes, the latter identified by mutations resulting in frame shift or premature truncation. During neuronal differentiation, nonfuncti
Autor:
James E. Schwob, Zhen Guo, Richard C. Krolewski, Glen L. Manglapus, Margaret T. Harris, Adam Packard
Publikováno v:
The Journal of Comparative Neurology. 518:4395-4418
The olfactory epithelium maintains stem and progenitor cells that support the neuroepithelium’s life-long capacity to reconstitute after injury. However, the identity of the stem cells – and their regulation – remain poorly defined. The transcr
Autor:
Eric Frank, Ken Rhodes, Richard C. Krolewski, David L. Kaplan, Karen L. Philpott, Marcie A. Glicksman, Cesare Spadoni, Marianne J. Ratcliffe, Karen Kotkow, Silvia Piccinotti, Piotr Graczyk, Andreas Eilers, Caroline Smales, Martin Raff, Howard Desmond, Alison Linsley O'Neil, Kostas Vekrellis, Freda D. Miller, Jonny Whitfield, Terrence Smith, Mary Jane McCarthy, Patrick Doherty, James E. Schwob, Ceren Ozek, Michael Klymkoswsky, Monica Mota Neumage, Joanne Taylor, Chantal E. Bazenet, Paul Lang, Karina F. Meiri, Feodor Price, Jonathan Ham, Fabian Gusovsky, Christine Gatchalian, Jane Relton
Publikováno v:
Science. 355:806-806
In her News Feature “Out of bounds” (27 January p. [339][1]), A. McCook strove to present an objective narrative of the situation in which a student at Harvard University was forced to undergo a psychiatric evaluation and then filed a court order