Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Richard C. Hewer"'
Autor:
Russell Burley, Richard C. Hewer, Martin Teall, Louise Dickson, Bernardino Ossola, Sam Russell, Clare Bender, Toni Cheung, Justin A.C. Powell, Xiao Xu, Nicola L. Brice, Lucy Otter, Marta Arimont, Sarah L. Kidd, David Vidal, James W. Dale, Lewis Mervin, Hannah F. Sore, Natalia Mateu, Narayana Lakshminarayana, Lee A. Dawson, Mark Carlton, Roland W. Bürli
Publikováno v:
Bioorganicmedicinal chemistry letters. 61
We report a significant decrease in transcription of the G protein-coupled receptor GPR39 in striatal neurons of Parkinson's disease patients compared to healthy controls, suggesting that a positive modulator of GPR39 may beneficially impact neuropro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ad575538566fdb73049d116f134aff
https://pubmed.ncbi.nlm.nih.gov/35123006
https://pubmed.ncbi.nlm.nih.gov/35123006
Autor:
Tomomi E. Kimura, Mark Bond, Aparna Duggirala, Andrew C. Newby, Charles C.T. Hindmarch, Richard C. Hewer, Mei-Zhen Cui
Publikováno v:
Journal of Molecular and Cellular Cardiology
Aims Cyclic AMP inhibits vascular smooth muscle cell (VSMC) proliferation which is important in the aetiology of numerous vascular diseases. The anti-mitogenic properties of cAMP in VSMC are dependent on activation of protein kinase A (PKA) and excha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5ce2c79cc8e7f46eb73e5dc8f8a8c85
https://doi.org/10.1016/j.yjmcc.2014.02.001
https://doi.org/10.1016/j.yjmcc.2014.02.001
Publikováno v:
Journal of Molecular and Cellular Cardiology
Cyclic AMP signalling promotes VSMC quiescence in healthy vessels and during vascular healing following injury. Cyclic AMP inhibits VSMC proliferation via mechanisms that are not fully understood. We investigated the role of PKA and Epac signalling o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ec138acc6fb657b561408435456207
http://europepmc.org/articles/PMC3093616
http://europepmc.org/articles/PMC3093616