Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Richard C A Sainson"'
Autor:
Stephan Weidinger, Michael Cork, Adam Reich, Thomas Bieber, Davide Lucchesi, Natalie Rynkiewicz, Richard C A Sainson, Ron Chen, Francesca Prandi, Cassandra van Krinks, Marisa Stebegg, Ben Porter-Brown
Publikováno v:
British Journal of Dermatology. 188
Amlitelimab (SAR445229), a fully human non-depleting, non-cytotoxic, monoclonal antibody, binds to OX40Ligand (OX40L) on antigen-presenting cells (APC) to block OX40-OX40L interactions. In a 16-week, double-blind, Phase 2a trial (NCT03754309), amlite
Autor:
Chern Ein, Oon, Esther, Bridges, Helen, Sheldon, Richard C A, Sainson, Adrian, Jubb, Helen, Turley, Russell, Leek, Francesca, Buffa, Adrian L, Harris, Ji-Liang, Li
Publikováno v:
Oncotarget
Delta-like 4 (DLL4) and Jagged1 (JAG1) are two key Notch ligands implicated in tumour angiogenesis. They were shown to have opposite effects on mouse retinal and adult regenerative angiogenesis. In tumours, both ligands are upregulated but their rela