Safety and function of a new pre-vascularized bioartificial pancreas in an allogeneic rat model

Autor: Jordan Magisson, Aladin Sassi, Daela Xhema, Aram Kobalyan, Pierre Gianello, Brice Mourer, Nguyen Tran, Charles-Thibault Burcez, Richard Bou Aoun, Séverine Sigrist

Publikováno v: Journal of Tissue Engineering, Vol 11 (2020)

Cell encapsulation could overcome limitations of free islets transplantation but is currently limited by inefficient cells immune protection and hypoxia. As a response to these challenges, we tested in vitro and in vivo the safety and efficacy of a n

Externí odkaz: https://doaj.org/article/3acf8689b75348ca8373d779d95b02c5

Enterocyte Purge and Rapid Recovery Is a Resilience Reaction of the Gut Epithelium to Pore-Forming Toxin Attack

Autor: Céline Keime, Kwang-Zin Lee, Stefanie Schirmeier, Dominique Ferrandon, Wennida Miriam Yamba, Caroline Spenlé, Yannick Schwab, Samuel Liégeois, Frédéric Dalle, Matthieu Lestradet, Catherine Socha, Olivier Lefebvre, Richard Bou Aoun, Patricia Simon-Assmann, Antonin Schmitz

Publikováno v: Cell Host and Microbe
Cell Host and Microbe, Elsevier, 2016, 20 (6), pp.716-730. ⟨10.1016/j.chom.2016.10.010⟩
Cell host & microbe
Cell host & microbe, 2016, 20 (6), pp.716-730. 〈10.1016/j.chom.2016.10.010〉

International audience; Besides digesting nutrients, the gut protects the host against invasion by pathogens. Enterocytes may be subjected to damage by both microbial and host defensive responses, causing their death. Here, we report a rapid epitheli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72fc2b8fa98cda50b1d518c7b3014942
https://pubmed.ncbi.nlm.nih.gov/27889464