Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Richard Borrows"'
Publikováno v:
BMC Medical Education, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Nephrology is a subject which is challenged by a lack of applicants for trainee places. This study addresses the attitudes of medical students towards the subject and explores the causes of this lack of interest amongst potential
Externí odkaz:
https://doaj.org/article/9fa5078b7e7d4ea1afdc0599e42f2108
Autor:
Dominic Stringer, Leanne Gardner, Olivia Shaw, Brendan Clarke, David Briggs, Judith Worthington, Matthew Buckland, Guilherme Danzi, Rachel Hilton, Michael Picton, Raj Thuraisingham, Richard Borrows, Richard Baker, Keith McCullough, John Stoves, Mysore Phanish, Sapna Shah, Kin Yee Shiu, Stephen B. Walsh, Aimun Ahmed, Waqar Ayub, Janet Hegarty, Rose Tinch-Taylor, Evangelos Georgiou, Natalie Bidad, Ayşenur Kılıç, Zoe Moon, Robert Horne, Paul McCrone, Joanna Kelly, Caroline Murphy, Janet Peacock, Anthony Dorling
Publikováno v:
EClinicalMedicine, Vol 56, Iss , Pp 101819- (2023)
Summary: Background: 3% of kidney transplant recipients return to dialysis annually upon allograft failure. Development of antibodies (Ab) against human leukocyte antigens (HLA) is a validated prognostic biomarker of allograft failure. We tested whet
Externí odkaz:
https://doaj.org/article/2c4d324f492b41508cbeb5d77c800b2e
Publikováno v:
BMC Nephrology, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background Improved recognition of factors influencing graft survival has led to better short-term kidney transplant outcomes. However, efforts to prevent long-term graft decline and improve graft survival have seen more modest improvements.
Externí odkaz:
https://doaj.org/article/e5d974b670494f729afdc87b9e50389a
Autor:
Nuvreen Phagura, BMedSci, Azm Hussain, MBBS, Alice Culliford, MBBS, James Hodson, BSc, Felicity Evison, MSc, Suzy Gallier, MSc, Richard Borrows, MA, Hanna A. Lane, PhD, David Briggs, PhD, Adnan Sharif, MD
Publikováno v:
Transplantation Direct, Vol 7, Iss 8, p e737 (2021)
Background. The association between specific HLA alleles and risk for posttransplantation diabetes (PTDM) in a contemporary and multiethnic kidney transplant recipient cohort is not clear. Methods. In this single-center analysis, data were retrospect
Externí odkaz:
https://doaj.org/article/9fb9bb0a71084d02afa9b28b601f4e79
Autor:
Dominic Stringer, Leanne M. Gardner, Janet L. Peacock, Irene Rebollo-Mesa, Rachel Hilton, Olivia Shaw, Richard Baker, Brendan Clark, Raj C. Thuraisingham, Matthew Buckland, Michael Picton, Judith Worthington, Richard Borrows, David Briggs, Sapna Shah, Kin Yee Shiu, Keith McCullough, Mysore Phanish, Janet Hegarty, John Stoves, Aimun Ahmed, Waqar Ayub, Robert Horne, Paul McCrone, Joanna Kelly, Caroline Murphy, Anthony Dorling
Publikováno v:
Trials, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background Chronic rejection is the single biggest cause of premature kidney graft failure. HLA antibodies (Ab) are an established prognostic biomarker for premature graft failure so there is a need to test whether treatment decisions based
Externí odkaz:
https://doaj.org/article/08a2f39e81b34e6a91eb89c65444c54f
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243278 (2020)
ObjectivesTo extrapolate the 'mood as information' theory to the unique and ecologically relevant setting of the COVID-19 pandemic; the specific aim was to inform health care providers of the impact of bringing the pandemic to salience during life sa
Externí odkaz:
https://doaj.org/article/51493615a63c455493ac96e65539f907
Autor:
Katherine Angela Benson, Sourabh Chand, Alexander Peter Maxwell, Laura Jane Smyth, Jill Kilner, Richard Borrows, Amy Jayne McKnight
Publikováno v:
BMC Research Notes, Vol 10, Iss 1, Pp 1-15 (2017)
Abstract Background Biologically active vitamin D has an important regulatory role within the genome. It binds the vitamin D receptor (VDR) in order to control the expression of a wide range of genes as well as interacting with the epigenome to modif
Externí odkaz:
https://doaj.org/article/7719752983a34bb1a9785c1f804e5237
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193968 (2018)
The measurement of CMV specific cellular immunity in organ transplant recipients could contribute additional acuity to serology based, CMV infection risk stratification, facilitating optimisation of immunosuppression and anti-viral prophylaxis.A pilo
Externí odkaz:
https://doaj.org/article/f88ac4dc5f7e4466a9d493706a09b7a8
Autor:
Sourabh Chand, David Atkinson, Clare Collins, David Briggs, Simon Ball, Adnan Sharif, Kassiani Skordilis, Bindu Vydianath, Desley Neil, Richard Borrows
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162278 (2016)
BACKGROUND:Causes of "true" late kidney allograft failure remain unclear as study selection bias and limited follow-up risk incomplete representation of the spectrum. METHODS:We evaluated all unselected graft failures from 2008-2014 (n = 171; 0-36 ye
Externí odkaz:
https://doaj.org/article/246ed5c2f13b48e2a3876c34a593fad9
Autor:
Sourabh Chand, Colin D Chue, Nicola C Edwards, James Hodson, Matthew J Simmonds, Alexander Hamilton, Stephen C L Gough, Lorraine Harper, Rick P Steeds, Jonathan N Townend, Charles J Ferro, Richard Borrows
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0116160 (2015)
Chronic kidney disease (CKD) is associated with accelerated cardiovascular disease and heart failure. Endothelial nitric oxide synthase (eNOS) Glu298Asp single nucleotide polymorphism (SNP) genotype has been associated with a worse phenotype amongst
Externí odkaz:
https://doaj.org/article/052e4a3a688f4ac1b8427321f84b839d