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of 15
pro vyhledávání: '"Richard Bickerton"'
Autor:
Noureddin Sadawi, Ivan Olier, Joaquin Vanschoren, Jan N. van Rijn, Jeremy Besnard, Richard Bickerton, Crina Grosan, Larisa Soldatova, Ross D. King
Publikováno v:
Journal of Cheminformatics, Vol 11, Iss 1, Pp 1-13 (2019)
Abstract The goal of quantitative structure activity relationship (QSAR) learning is to learn a function that, given the structure of a small molecule (a potential drug), outputs the predicted activity of the compound. We employed multi-task learning
Externí odkaz:
https://doaj.org/article/7cee0a9bcc56463797a9e229cb270508
Autor:
Zahir Mughal, Ramanathan Swaminathan, Husham B Al-Deerawi, Scott E. Henney, Richard Bickerton
Publikováno v:
Cureus
Background: There is a perception among ear, nose, and throat (ENT) surgeons that oral antibiotics are over-prescribed for acute otitis externa (AOE), and the potential for topical therapy as first-line treatment is not fully realized in primary care
Publikováno v:
BMJ case reports. 2017
A 65-year-old man with a 2-month history of left-sided neck swelling presented through the cancer pathway. There was no associated ‘red flag’ symptoms, and clinical examination revealed a left anterior triangle, non-pulsatile firm swelling atypic
Autor:
Craig Johnstone, Michael R. Paillasse, Pierre Fons, Richard Bickerton, Gigliola Mambrini, Michael Esquerre, Andrew L. Hopkins, Françoise Bono, Joanna Lisztwan, Andrew Simon Bell, Stephanie Versluys, Adrian Schreyer, Mark Whittaker, Richard Cox
Publikováno v:
Cancer Research. 77:3970-3970
Standard Immune Checkpoint Therapies, such as anti-CTLA-4 or anti-PD-1/PD-L1 mAb, demonstrate long progression-free-survival for responding patients but with a low response rate. This can be due to additional immunosuppressive mechanisms developed by
Publikováno v:
Journal of Surgical Case Reports
This was an unusual case of lacrimal sac compression by an anterior ethmoidal mucocele presenting as a late complication of a dacryocystorhinostomy (DCR) that was jointly managed by ophthalmic and ENT surgeons via an endoscopic approach. A 22-year-ol
Autor:
Alison Baylay, Alicia P. Higueruelo, Tom L. Blundell, George Richard Bickerton, Semin Lee, Adrian Schreyer, William R. Pitt, Duangrudee Tanramluk, Sungsam Gong, Alan Brown
Publikováno v:
Molecular bioSystems. 5(12)
Here we review the use of informatics in structural interactomics, with particular emphasis on understanding interfacial contacts in the development of novel therapeutics and the interpretation of genetic variation. We describe the availability and a
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics, Vol 12, Iss 1, p 313 (2011)
BMC Bioinformatics, Vol 12, Iss 1, p 313 (2011)
Background Structural studies are increasingly providing huge amounts of information on multi-protein assemblies. Although a complete understanding of cellular processes will be dependent on an explicit characterization of the intermolecular interact
Autor:
L. Hopkins, Andrew, Richard Bickerton, G., M. Carruthers, Ian, K. Boyer, Stephen, Rubin, Harvey, P. Overington, John
Publikováno v:
Current Topics in Medicinal Chemistry; May 2011, Vol. 11 Issue: 10 p1292-1300, 9p
Autor:
Richard Bickerton
Publikováno v:
Public Personnel Management. 16:349-358
We live in an age when information and technology are of primary importance to our lives. Those who control information, and its timely and credible dissemination, wield great power. This is also true in the EAP field. The ALMACA Clearinghouse for Em
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