Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Richard Banh"'
Autor:
Daohua Jiang, Lige Tonggu, Tamer M. Gamal El-Din, Richard Banh, Régis Pomès, Ning Zheng, William A. Catterall
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The α-toxin LqhIII from the deathstalker scorpion inhibits fast inactivation of cardiac NaV1.5 channels. Here authors reveal the cryo-EM structure of LqhIII bound to NaV1.5 which shows that LqhIII traps the gating charges of the S4 segment in a uniq
Externí odkaz:
https://doaj.org/article/551ce5bc8824402bb013e154205ef0bc
Autor:
Régis Pomès, Deri Morgan, Sarah Thomas, Richard Banh, Boris Musset, Thomas E. DeCoursey, Kethika Kulleperuma, Susan M.E. Smith, Vladimir V. Cherny
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance A large family of membrane proteins, voltage-gated ion channels, regulate a vast array of physiological functions in essentially all life forms. How these molecules sense membrane potential and respond by creating ionic conduction is inc
Autor:
Régis Pomès, Daohua Jiang, Tamer M. Gamal El-Din, Richard Banh, Lige Tonggu, Ning Zheng, William A. Catterall
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
Voltage-gated sodium (NaV) channels initiate action potentials in excitable cells, and their function is altered by potent gating-modifier toxins. The α-toxin LqhIII from the deathstalker scorpion inhibits fast inactivation of cardiac NaV1.5 channel
Autor:
Régis Pomès, Richard Banh, Ning Zheng, Daohua Jiang, T.M. Gamal El-Din, Lige Tonggu, William A. Catterall
Voltage-gated sodium (NaV) channels initiate action potentials in excitable cells, and their function is altered by potent gating-modifier toxins. The α-toxin LqhIII from the deathstalker scorpion inhibits fast inactivation of cardiac NaV1.5 channel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46fb2645cc94482f13d9d2e905ad75ac
https://doi.org/10.1101/2020.12.28.424592
https://doi.org/10.1101/2020.12.28.424592
Autor:
Michael J. Lenaeus, Régis Pomès, Tamer M. Gamal El-Din, Ning Zheng, Richard Banh, William A. Catterall, Lige Tonggu, Daohua Jiang
Publikováno v:
Cell
The heartbeat is initiated by voltage-gated sodium channel Na(V)1.5, which opens rapidly and triggers the cardiac action potential; however, the structural basis for pore opening remains unknown. Here we blocked fast inactivation with a mutation and
Autor:
Thomas E. DeCoursey, Richard Banh, Kethika Kulleperuma, Régis Pomès, Vladimir V. Cherny, Sarah Thomas, Susan M.E. Smith, Deri Morgan, Boris Musset
Publikováno v:
Biophysical Journal. 118:273a-274a
Publikováno v:
Biophysical Journal. 118:17a
Autor:
Thomas E. DeCoursey, Régis Pomès, Susan M.E. Smith, Sarah Thomas, Richard Banh, Deri Morgan, Kethika Kulleperuma, Vladimir V. Cherny, Boris Musset
Publikováno v:
Biophysical Journal. 116:173a