Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Richard B. Greaves"'
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Type 1 diabetes (T1d) results from a sustained autoreactive T and B cell response towards insulin-producing β cells in the islets of Langerhans. The autoreactive nature of the condition has led to many investigations addressing the genetic or cellul
Externí odkaz:
https://doaj.org/article/8ddec431866b49e3bf36f3d94fe73ec2
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 9, p e1005713 (2017)
The capacity of pluripotent embryonic stem cells to differentiate into any cell type in the body makes them invaluable in the field of regenerative medicine. However, because of the complexity of both the core pluripotency network and the process of
Externí odkaz:
https://doaj.org/article/4e7092c5c9ce42feaa143d9ccc1a5031
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Type 1 diabetes (T1d) results from a sustained autoreactive T and B cell response towards insulin-producing β cells in the islets of Langerhans. The autoreactive nature of the condition has led to many investigations addressing the genetic or cellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a82b0b16a26a103cb61fe1d51ce3dc
https://www.frontiersin.org/articles/10.3389/fimmu.2021.772017/full
https://www.frontiersin.org/articles/10.3389/fimmu.2021.772017/full
Autor:
Mark Read, Paul S Andrews, Jon Timmis, Richard A Williams, Richard B Greaves, Huiming Sheng, Mark Coles, Vipin Kumar
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128170 (2015)
Externí odkaz:
https://doaj.org/article/ac74dc23ccdc460c947fc81a0f811497
Autor:
Mark Read, Paul S Andrews, Jon Timmis, Richard A Williams, Richard B Greaves, Huiming Sheng, Mark Coles, Vipin Kumar
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80506 (2013)
Predicting efficacy and optimal drug delivery strategies for small molecule and biological therapeutics is challenging due to the complex interactions between diverse cell types in different tissues that determine disease outcome. Here we present a n
Externí odkaz:
https://doaj.org/article/5f9e0108f8994c6e80e90e811a40b63a
Publikováno v:
Complexity. 19:73-82
Complex social-ecological systems SES are not amenable to simple mathematical modeling. However, to address critical issues in SES e.g., understanding ecological resilience/amelioration of poverty it is necessary to describe such systems in their ent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7aba2c3b7ff311033c8418e619b4ac
https://doi.org/10.1002/cplx.21524
https://doi.org/10.1002/cplx.21524
Publikováno v:
Scopus-Elsevier
Activation of herpes simplex virus immediate early gene expression normally requires the formation of a ternary complex between a virus trans-activator, Vmw65, a cellular octamer-binding protein, TRF and the cis-acting target sequence, the TAATGARAT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::216fd62ca010cbdbc7d55d45d9308a70
https://ora.ox.ac.uk/objects/uuid:52013cf9-3d4f-4aaa-9edf-a3a8b2774ea1
https://ora.ox.ac.uk/objects/uuid:52013cf9-3d4f-4aaa-9edf-a3a8b2774ea1
Autor:
Jim Warwicker, Richard B. Greaves
Publikováno v:
Biochemical and Biophysical Research Communications. 380:581-585
Charges are important for hyperthermophile protein structure and function. However, the number of charges and their predicted contributions to folded state stability are not correlated, implying that more charge does not imply greater stability. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add00674394940cfa703f5927e160c78
https://doi.org/10.1016/j.bbrc.2009.01.145
https://doi.org/10.1016/j.bbrc.2009.01.145
Autor:
Robert A. S. Ariëns, D. Alastair Smith, Robert Harrand, John W. Weisel, Ramzi A. Ajjan, Fladia Phoenix, Sarah Dolling, Kristina F. Standeven, Simon D. Connell, Bernard C. B. Lim, Peter J. Grant, Richard B. Greaves, Radwa H. Abou-Saleh
Publikováno v:
Blood. 111:643-650
Fibrinogen BβArg448Lys is a common polymorphism, positioned within the carboxyl terminus of the Bβ-chain of the molecule. Studies suggest that it is associated with severity of coronary artery disease and development of stroke. The effects of the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66bb612ef9841fe45c5bfc95c3f5404
https://doi.org/10.1182/blood-2007-05-091231
https://doi.org/10.1182/blood-2007-05-091231
Autor:
Huiming Sheng, Richard B. Greaves, Mark Coles, Richard A Williams, Jon Timmis, Mark Read, Paul S. Andrews, Vipin Kumar
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128170 (2015)
The image for Fig 4C is incorrect. Please see the complete, corrected Fig 4 here. Fig 4 Effector T cell and clinical disease dynamics given anti-CD3 intervention at day 4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1c951a7bed0774ecbab346f02616eb
http://europepmc.org/articles/PMC4425704?pdf=render
http://europepmc.org/articles/PMC4425704?pdf=render