Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Richard B. Dause"'
Autor:
J. Craig Franklin, Yan Zha, Andrew S. Janoff, Walter Perkins, Donna Cabral-Lilly, Richard B. Dause, Eric Mayhew, Xingong Li, Eugene H Dank
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1327(1):61-68
Because the therapeutic use of the antitumor ether lipid 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphorylcholine (ET-18-OCH3) is restricted by its hemolytic activity we explored the use of lipid packing parameters to reduce this toxicity by creating
Autor:
Richard B. Dause, W. Mark Saltzman, J. Alan Pratt, Amy M. Dodrill, Norman F. Sheppard, Mark A. McHugh
Publikováno v:
Journal of Applied Polymer Science. 48:1493-1500
A new method is presented for controlling the rate of antibody (Ab) release from an inert matrix composed of poly(ethylene-co-vinyl acetate) (EVAc), a biocompatible polymer that is frequently used to achieve controlled release. Using supercritical pr
Autor:
Theodore F. Taraschi, Sol M. Gruner, Andrew S. Janoff, Keir C. Neuman, Sharma R. Minchey, Walter Perkins, Richard B. Dause, Roberta A. Parente
Publikováno v:
Science. 273:330-332
The development of artificial surfactants for the treatment of respiratory distress syndrome (RDS) requires lipid systems that can spread rapidly from solution to the air-water interface. Because hydration-repulsion forces stabilize liposomal bilayer
Autor:
Rachel Stevens, Walter Perkins, Andrew S. Janoff, Patricia Roberts, Richard B. Dause, Patrick L. Ahl, Bhatia Suresh K, Paul Meers
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (2):370-382
Incorporation of N-(omega-carboxy)acylamido-phosphatidylethanolamines (-PEs) into large unilamellar vesicles (LUVs) of L-alpha-distearoylphosphatidylcholine (DSPC) was found to dramatically increase the in vivo liposomal circulation lifetime in rats,
Autor:
J. Craig Franklin, Yan Zha, Richard B. Dause, Elizabet Kaisheva, Walter Perkins, Eric Mayhew, Andrew S. Janoff, Imran Ahmad, Julius Filep, Bhatia Suresh K
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (1):139-148
The ether lipid, 1- O -octadecyl-2- O -methyl-sn-glycero-3-phosphocholine (ET-18-OCH 3 ), has anticancer activity, but it has serious side-effects, including hemolysis, which prevent its optimal use. We surmised if ET-18-OCH 3 could be stably associa