Zobrazeno 1 - 10
of 219
pro vyhledávání: '"Richard B Meagher"'
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009699 (2021)
Globally, there are several million individuals with life-threatening invasive fungal diseases such as candidiasis, aspergillosis, cryptococcosis, Pneumocystis pneumonia (PCP), and mucormycosis. The mortality rate for these diseases generally exceeds
Externí odkaz:
https://doaj.org/article/d6828e4d692e4637ac1e8a5ce18175f5
Autor:
Ping Yu, Lexiang Ji, Kevin J Lee, Miao Yu, Chuan He, Suresh Ambati, Elizabeth C McKinney, Crystal Jackson, Clifton A Baile, Robert J Schmitz, Richard B Meagher
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154949 (2016)
The reprogramming of cellular memory in specific cell types, and in visceral adipocytes in particular, appears to be a fundamental aspect of obesity and its related negative health outcomes. We explored the hypothesis that adipose tissue contains epi
Externí odkaz:
https://doaj.org/article/cefd771e2c0b4affad2a9af7f5d9a8a9
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145917 (2015)
The actin-depolymerizing factor/cofilin (ADF/CFL) gene family encodes a diverse group of relatively small proteins. Once known strictly as modulators of actin filament dynamics, recent research has demonstrated that these proteins are involved in a v
Externí odkaz:
https://doaj.org/article/25598e5217b5443991d705cfa74f9f59
Publikováno v:
Journal of Fungi, Vol 8, Iss 4, p 352 (2022)
Mucormycosis (a.k.a. zygomycosis) is an often-life-threatening disease caused by fungi from the ancient fungal division Mucoromycota. Globally, there are nearly a million people with the disease. Rhizopus spp., and R. delemar (R. oryzae, R. arrhizus)
Externí odkaz:
https://doaj.org/article/775428a7b1264b03bda228a830c6587a
Publikováno v:
Advanced Drug Delivery Reviews. 196:114776
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4be8f2b05a14233a77fdeeb706eb3ed
https://doi.org/10.1016/j.addr.2023.114776
https://doi.org/10.1016/j.addr.2023.114776
Publikováno v:
Sleep & Breathing = Schlaf & Atmung
Purpose Obstructive sleep apnea (OSA) results in systemic intermittent hypoxia. By one model, hypoxic stress signaling in OSA patients alters the levels of inflammatory soluble cytokines TNF and IL6, damages the blood brain barrier, and activates mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c2b23fadcfc1d75d08e5252da2f72e2
https://doi.org/10.1007/s11325-020-02205-y
https://doi.org/10.1007/s11325-020-02205-y
Publikováno v:
Antimicrobial Agents and Chemotherapy
Candida albicans causes life-threatening disseminated candidiasis. Individuals at greatest risk have weakened immune systems. An outer cell wall, exopolysaccharide matrix, and biofilm rich in oligoglucans and oligomannans help Candida spp. evade host
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9870e6eec069cccb53c7684342e1debf
http://europepmc.org/articles/PMC8765427
http://europepmc.org/articles/PMC8765427
Publikováno v:
Fungal Biology and Biotechnology
Fungal Biology and Biotechnology, Vol 8, Iss 1, Pp 1-13 (2021)
Fungal Biology and Biotechnology, Vol 8, Iss 1, Pp 1-13 (2021)
Background Life-threatening invasive fungal infections are treated with antifungal drugs such as Amphotericin B (AmB) loaded liposomes. Our goal herein was to show that targeting liposomal AmB to fungal cells with the C-type lectin pathogen recogniti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df699684ec871d6e9a150e7bcd636a4
https://pubmed.ncbi.nlm.nih.gov/34952645
https://pubmed.ncbi.nlm.nih.gov/34952645
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009699 (2021)
PLoS Pathogens
PLoS Pathogens
Globally, there are several million individuals with life-threatening invasive fungal diseases such as candidiasis, aspergillosis, cryptococcosis, Pneumocystis pneumonia (PCP), and mucormycosis. The mortality rate for these diseases generally exceeds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6442c751d94af48fe5a6730ba239b78e
https://doaj.org/article/d6828e4d692e4637ac1e8a5ce18175f5
https://doaj.org/article/d6828e4d692e4637ac1e8a5ce18175f5
Autor:
Richard B. Meagher, Tuyetnhu Pham, Emma C. Ellis, Xiaorong Lin, Zachary A. Lewis, Suresh Ambati
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
mBio
mBio
Invasive fungal diseases cause millions of deaths each year. There are currently approximately 300,000 acute cases of aspergillosis, most of which result from a pulmonary infection of immunocompromised patients by the common soil organism and opportu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab80ca78f1f6643b1b0935b2cd0de21
https://doi.org/10.1128/mbio.00030-21
https://doi.org/10.1128/mbio.00030-21