Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Richard B McCosh"'
Publikováno v:
Endocrinology. 163(9)
A major obstacle to monitoring pulsatile luteinizing hormone (LH) secretion in mice has been an assay with sufficient sensitivity in small blood volumes. In 2013, Steyn and colleagues published a highly sensitive enzyme-linked immunosorbent assay (EL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc8d1185c6ad6bc6fce093f3aeb2cd05
https://pubmed.ncbi.nlm.nih.gov/35929775
https://pubmed.ncbi.nlm.nih.gov/35929775
Publikováno v:
J Endocrinol
Peripheral immune/inflammatory challenges rapidly disrupt reproductive neuroendocrine function. This inhibition is considered to be centrally mediated via suppression of gonadotropin-releasing hormone secretion, yet the neural pathway(s) for this eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830af544198c0e49bf7e40564d27a05b
https://doi.org/10.1530/joe-20-0165
https://doi.org/10.1530/joe-20-0165
Publikováno v:
J Neuroendocrinol
The effect of stress on reproduction and gonadal function has captivated investigators for almost 100 years. Following the identification of gonadotropin-releasing hormone (GnRH) 50 years ago, a niche research field emerged fixated on how stress impa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac3dab93467e89c922e4d6aa91600138
https://doi.org/10.1111/jne.13098
https://doi.org/10.1111/jne.13098
Publikováno v:
Endocrinology
Chronic undernutrition is a type of metabolic stress that impairs reproduction in multiple species. Although energy balance and female reproductive capacity is recognized as tightly coupled, the neuroendocrine loci and molecular mechanisms that media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::775fd339694caf073231b531669a24f6
https://doi.org/10.1210/endocr/bqab103
https://doi.org/10.1210/endocr/bqab103
Autor:
Clay A. Lents, Stanley M. Hileman, Samantha A Young, Richard B McCosh, Michelle N Bedenbaugh, Jennifer F. Thorson, Chrysanthi Fergani, Ashley N. Lindo, Justin A Lopez, Michael N. Lehman, B. A. Freking, Elizabeth C. Bowdridge, Lanny J. Meadows
Publikováno v:
Biol Reprod
Mechanisms in the brain controlling secretion of gonadotropin hormones in pigs, particularly luteinizing hormone (LH), are poorly understood. Kisspeptin is a potent LH stimulant that is essential for fertility in many species, including pigs. Neuroki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c68318bd997f7455d46677a518f85a
https://pubmed.ncbi.nlm.nih.gov/34037695
https://pubmed.ncbi.nlm.nih.gov/34037695
Autor:
Justin A Lopez, Makayla Metzger, Ashley N. Lindo, Richard B McCosh, Robert L. Goodman, Elizabeth C. Bowdridge, Megan Haller, Michelle N Bedenbaugh, Michael N. Lehman, Stanley M. Hileman
Publikováno v:
J Neuroendocrinol
Neurokinin B (NKB) is critical for fertility in humans and stimulates gonadotrophin-releasing hormone/luteinising hormone (LH) secretion in several species, including sheep. There is increasing evidence that the actions of NKB in the retrochiasmatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77af237c3b95b824500f7dce78164bb
https://europepmc.org/articles/PMC7449597/
https://europepmc.org/articles/PMC7449597/
Autor:
Michael N. Lehman, Makayla Metzger, Ashley N. Lindo, Michelle N Bedenbaugh, Stanley M. Hileman, Richard B McCosh, Justin A Lopez, Elizabeth C. Bowdridge, Megan Haller, Robert L. Goodman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b214620b02943e97c9b0e6131073601
https://doi.org/10.1111/jne.12877/v2/response1
https://doi.org/10.1111/jne.12877/v2/response1
Publikováno v:
Journal of the Endocrine Society
Pulsatile luteinizing hormone (LH) secretion is disrupted by numerous stimuli including metabolic stress. Insulin-induced hypoglycemia is a model of metabolic stress that suppresses LH secretion in numerous species including mice. Our recent work pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::659f375bdcf4e7a69457291f2511a7b6
https://doi.org/10.1210/jendso/bvaa046.1075
https://doi.org/10.1210/jendso/bvaa046.1075
Autor:
Stanley M. Hileman, Lique M. Coolen, Brett M Szeligo, Richard B McCosh, Robert L. Goodman, Michelle N Bedenbaugh, Michael N. Lehman, Justin A Lopez
Publikováno v:
Endocrinology
Elevated and sustained estradiol concentrations cause a gonadotropin-releasing hormone (GnRH) and luteinizing hormone (LH) surge that is necessary for ovulation. In sheep, several different neural systems have been implicated in this stimulatory acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72bae17d2dd40ec5777e2a60830c11f3
https://doi.org/10.1210/endocr/bqaa010
https://doi.org/10.1210/endocr/bqaa010
Publikováno v:
Mol Cell Endocrinol
Stress is well-known to inhibit a variety of reproductive processes, including the suppression of episodic Gonadotropin releasing hormone (GnRH) secretion, typically measured via downstream luteinizing hormone (LH) secretion. Since pulsatile secretio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ecf4aba93fcf84817b7f7dafb22fd4
https://escholarship.org/uc/item/4nx3t9p4
https://escholarship.org/uc/item/4nx3t9p4