Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Richard B Cooley"'
Publikováno v:
eLife, Vol 5 (2016)
The second messenger c-di-GMP (or cyclic diguanylate) regulates biofilm formation, a physiological adaptation process in bacteria, via a widely conserved signaling node comprising a prototypical transmembrane receptor for c-di-GMP, LapD, and a cognat
Externí odkaz:
https://doaj.org/article/1c25c1d1b9e04017bcb0f8dc87dd830c
Autor:
Debashree Chatterjee, Richard B Cooley, Chelsea D Boyd, Ryan A Mehl, George A O'Toole, Holger Sondermann
Publikováno v:
eLife, Vol 3 (2014)
Stable surface adhesion of cells is one of the early pivotal steps in bacterial biofilm formation, a prevalent adaptation strategy in response to changing environments. In Pseudomonas fluorescens, this process is regulated by the Lap system and the s
Externí odkaz:
https://doaj.org/article/1a908a9476a04e1f807be5dd4f8753cb
Autor:
Grace D. Galles, Daniel T. Infield, Colin J. Clark, Marcus L. Hemshorn, Shivani Manikandan, Frederico Fazan, Ali Rasouli, Emad Tajkhorshid, Jason D. Galpin, Richard B. Cooley, Ryan A. Mehl, Christopher A. Ahern
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Aromatic amino acids in proteins support ligand binding and protein stability. To parse the physiocochemical roles of aromatic interactions, here Galles, Infield and co-authors identify pyrrolysine-based aminoacyl-tRNA synthetases that enable the enc
Externí odkaz:
https://doaj.org/article/bf16f9a0529447d48911d7bab7bf37ef
Autor:
Elise M. Van Fossen, Sonia Grutzius, Carl E. Ruby, Dan V. Mourich, Chris Cebra, Shay Bracha, P. Andrew Karplus, Richard B. Cooley, Ryan A. Mehl
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
A critical step in developing therapeutics for oxidative stress-related pathologies is the ability to determine which specific modified protein species are innocuous by-products of pathology and which are causative agents. To achieve this goal, techn
Externí odkaz:
https://doaj.org/article/e7ee875dac2c4ee68361d8663535c867
Autor:
Phillip Zhu, Stanislau Stanisheuski, Rachel Franklin, Amber Vogel, Cat Hoang Vesely, Patrick Reardon, Nikolai N. Sluchanko, Joseph S. Beckman, P. Andrew Karplus, Ryan A. Mehl, Richard B. Cooley
Publikováno v:
ACS Central Science. 9:816-835
Publikováno v:
ACS Chemical Biology. 17:3470-3477
Autor:
Savanna Avila-Crump, Marcus L. Hemshorn, Chloe M. Jones, Lea Mbengi, Kyle Meyer, Joshua A. Griffis, Subhashis Jana, Grace E. Petrina, Vinayak V. Pagar, P. Andrew Karplus, E. James Petersson, John J. Perona, Ryan A. Mehl, Richard B. Cooley
Publikováno v:
ACS Chemical Biology. 17:3458-3469
Autor:
Anna A. Kapitonova, Kristina V. Tugaeva, Larisa A. Varfolomeeva, Konstantin M. Boyko, Richard B. Cooley, Nikolai N. Sluchanko
Publikováno v:
Biochemical and Biophysical Research Communications. 627:176-183
Nucleophosmin 1 (NPM1) is a multifunctional protein regulating ribosome biogenesis, centrosome duplication and chromatin remodeling. Being a major nucleolar protein, NPM1 can migrate to the nucleus and the cytoplasm, which is controlled by changes of
Autor:
Giordan Kitts, Krista M. Giglio, David Zamorano-Sánchez, Jin Hwan Park, Loni Townsley, Richard B. Cooley, Benjamin R. Wucher, Karl E. Klose, Carey D. Nadell, Fitnat H. Yildiz, Holger Sondermann
Publikováno v:
mBio, Vol 10, Iss 6 (2019)
ABSTRACT The dinucleotide second messenger c-di-GMP has emerged as a central regulator of reversible cell attachment during bacterial biofilm formation. A prominent cell adhesion mechanism first identified in pseudomonads combines two c-di-GMP-mediat
Externí odkaz:
https://doaj.org/article/9a8a543adaa141dcaa3c9dfe3f2eca0c
Autor:
Phillip Zhu, Kyle T. Nguyen, Aidan B. Estelle, Nikolai N. Sluchanko, Ryan A. Mehl, Richard B. Cooley
Publikováno v:
Protein Science. 32
14-3-3 proteins are central hub regulators of hundreds of phosphorylated “client” proteins. They are subject to over 60 post-translational modifications (PTMs), yet little is known how these PTMs alter 14-3-3 function and its ability to regulate