Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Richard B, Schwab"'
Autor:
Rebecca A. Shatsky, Hemali Batra-Sharma, Teresa Helsten, Richard B. Schwab, Emily I. Pittman, Minya Pu, Elizabeth Weihe, Emanuela M. Ghia, Laura Z. Rassenti, Alfredo Molinolo, Betty Cabrera, James B. Breitmeyer, George F. Widhopf, Karen Messer, Catriona Jamieson, Thomas J. Kipps, Barbara A. Parker
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-10 (2024)
Abstract Background Zilovertamab is a humanized monoclonal antibody targeting ROR1, an onco-embryonic antigen expressed by malignant cells of a variety of solid tumors, including breast cancer. A prior phase 1 study showed that zilovertamab was well
Externí odkaz:
https://doaj.org/article/0486bdf60d074a82b6fba59959ed172b
Autor:
Rebecca A. Shatsky, Hemali Batra-Sharma, Teresa Helsten, Richard B. Schwab, Emily I. Pittman, Minya Pu, Elizabeth Weihe, Emanuela M. Ghia, Laura Z. Rassenti, Alfredo Molinolo, Betty Cabrera, James B. Breitmeyer, George F. Widhopf II, Karen Messer, Catriona Jamieson, Thomas J. Kipps, Barbara A. Parker
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/e6112c11579145ef905f2712d4ff134a
Autor:
Amy S. Clark, Christina Yau, Denise M. Wolf, Emanuel F. Petricoin, Laura J. van ‘t Veer, Douglas Yee, Stacy L. Moulder, Anne M. Wallace, A. Jo Chien, Claudine Isaacs, Judy C. Boughey, Kathy S. Albain, Kathleen Kemmer, Barbara B. Haley, Hyo S. Han, Andres Forero-Torres, Anthony Elias, Julie E. Lang, Erin D. Ellis, Rachel Yung, Debu Tripathy, Rita Nanda, Julia D. Wulfkuhle, Lamorna Brown-Swigart, Rosa I. Gallagher, Teresa Helsten, Erin Roesch, Cheryl A. Ewing, Michael Alvarado, Erin P. Crane, Meredith Buxton, Julia L. Clennell, Melissa Paoloni, Smita M. Asare, Amy Wilson, Gillian L. Hirst, Ruby Singhrao, Katherine Steeg, Adam Asare, Jeffrey B. Matthews, Scott Berry, Ashish Sanil, Michelle Melisko, Jane Perlmutter, Hope S. Rugo, Richard B. Schwab, W. Fraser Symmans, Nola M. Hylton, Donald A. Berry, Laura J. Esserman, Angela M. DeMichele
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
HER2-targeted therapy improves patient’s outcome in early breast cancer. Here, the authors present the efficacy and biomarker analysis of two HER2-targeted combinations (ado-trastuzumab emtansine plus pertuzumab and paclitaxel, trastuzumab and pert
Externí odkaz:
https://doaj.org/article/e6340916dac6476fac8b24ed5afd32c1
Autor:
Shumei Kato, Ki Hwan Kim, Hyo Jeong Lim, Amelie Boichard, Mina Nikanjam, Elizabeth Weihe, Dennis J. Kuo, Ramez N. Eskander, Aaron Goodman, Natalie Galanina, Paul T. Fanta, Richard B. Schwab, Rebecca Shatsky, Steven C. Plaxe, Andrew Sharabi, Edward Stites, Jacob J. Adashek, Ryosuke Okamura, Suzanna Lee, Scott M. Lippman, Jason K. Sicklick, Razelle Kurzrock
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
A molecular tumor board (MTB) is often used as a platform that integrates clinical and molecular parameters for clinical decision making. Here, the authors review the outcome of 715 cancer patients presented at their institution’s MTB, and demonstr
Externí odkaz:
https://doaj.org/article/be2daa0bb1884adbb304041e571d8edf
Autor:
Yazmin San Miguel, Scarlett Lin Gomez, James D. Murphy, Richard B. Schwab, Corinne McDaniels-Davidson, Alison J. Canchola, Alfredo A. Molinolo, Jesse N. Nodora, Maria Elena Martinez
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background We assessed breast cancer mortality in older versus younger women according to race/ethnicity, neighborhood socioeconomic status (nSES), and health insurance status. Methods The study included female breast cancer cases 18 years o
Externí odkaz:
https://doaj.org/article/562ac8727757431e938ae9722d7c75ef
Autor:
Sung-Bae Kim, Hope S Rugo, Sara A Hurvitz, Hong-Tai Chang, Chiun-Sheng Huang, Su-Hua Lee, Jung-Tung Hung, Shir-Hwa Ueng, Shin-Cheh Chen, Alice L Yu, Ling-Ming Tseng, Louis W C Chow, Ming-Feng Hou, Richard B Schwab, James L Murray, Hsien-Kun Chang, Chwen-Cheng Chen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Purpose This randomized, double-blind, placebo-controlled, parallel-group, phase II trial assessed the efficacy and safety of adagloxad simolenin (OBI-822; a Globo H epitope covalently linked to keyhole limpet hemocyanin (KLH)) with adjuvant OBI-821
Externí odkaz:
https://doaj.org/article/6edfc74c39b5454884784f7a49c0a626
Autor:
Matteo D′Antonio, Donate Weghorn, Agnieszka D′Antonio-Chronowska, Florence Coulet, Katrina M. Olson, Christopher DeBoever, Frauke Drees, Angelo Arias, Hakan Alakus, Andrea L. Richardson, Richard B. Schwab, Emma K. Farley, Shamil R. Sunyaev, Kelly A Frazer
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Cancer driver mutations can occur within noncoding genomic sequences. Here, the authors develop a statistical approach to identify candidate noncoding driver mutations in DNase I hypersensitive sites in breast cancer and experimentally demonstrate th
Externí odkaz:
https://doaj.org/article/fed8c71471284e789fe9fe3936d957c5
Autor:
Razelle Kurzrock, Barbara A. Parker, Kelly A. Shimabukuro, Richard B. Schwab, Paul T. Fanta, David E. Piccioni, Gregory A. Daniels, Maria Schwaederle
Despite the increased use of molecular diagnostics, the extent to which patients who have these tests harbor potentially actionable aberrations is unclear. We retrospectively reviewed 439 patients with diverse cancers, for whom next-generation sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::058e4b1109886d1a1ecbcc1c7fec407b
https://doi.org/10.1158/1535-7163.c.6536761.v1
https://doi.org/10.1158/1535-7163.c.6536761.v1
Autor:
Razelle Kurzrock, Scott M. Lippman, Paul T. Fanta, Julio Romero, Lyudmila A. Bazhenova, Teresa L. Helsten, Santosh Kesari, David E. Piccioni, Gregory A. Daniels, Richard B. Schwab, Barbara A. Parker, Maria Schwaederle
By profiling their patients' tumors, oncologists now have the option to use molecular results to match patients with drug(s) based on specific biomarkers. In this observational study, 347 patients with solid advanced cancers and next-generation seque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d38652e4f16dcdeda5f7bb5f11ff928f
https://doi.org/10.1158/1535-7163.c.6538405.v1
https://doi.org/10.1158/1535-7163.c.6538405.v1
Autor:
Razelle Kurzrock, Scott M. Lippman, Paul T. Fanta, Julio Romero, Lyudmila A. Bazhenova, Teresa L. Helsten, Santosh Kesari, David E. Piccioni, Gregory A. Daniels, Richard B. Schwab, Barbara A. Parker, Maria Schwaederle
Supplemental Methods 1) Sequencing: (182 and 236 gene lists) 2)Therapy 3) Matching Score 4) Statistical Analysis (patient's characteristics, study endpoints and definitions, analyses performed);Supplemental Table 1. Patient characteristics; Supplemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e4f8a450bacecb9c256df081ef4ca4
https://doi.org/10.1158/1535-7163.22506457
https://doi.org/10.1158/1535-7163.22506457