Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Richard B, Rosse"'
Autor:
Murray B. Stein, Thomas D. Geracioti, Cristine Cusin, Xiaoying Sun, Rema Raman, Gail M. Farfel, Jennifer C. Naylor, Christine E. Marx, James B. Lohr, Julia Tsai, Ariel J. Lang, Mark B. Hamner, Ann M. Rasmusson, Sonia Jain, Lanier Summerall, Richard B. Rosse
Publikováno v:
Psychopharmacology. 234:2245-2257
Preclinical and clinical research supports a role for neuroactive steroids in the pathophysiology of posttraumatic stress disorder (PTSD). We investigated ganaxolone (a synthetic 3β-methylated derivative of allopregnanolone, a GABAergic neuroactive
Autor:
Clayton H. Brown, Richard B. Rosse, Nina Schooler, Stephanie M. Rosse, Barbara L. Schwartz, Stephen I. Deutsch
Publikováno v:
Schizophrenia Research. 148:138-144
Alpha7 nicotinic acetylcholine receptor (α7 nAChR) agonists may be valuable treatments for negative symptoms and cognitive impairment in schizophrenia. Unfortunately, chronic exposure to an agonist may reduce the receptor’s sensitivity. Therefore,
Publikováno v:
Military Medicine. 175:1030-1036
A 41-year-old male sustained a massive crushing injury to his left posterior thigh and buttock and transection of the sciatic nerve; he underwent an above-knee amputation with fillet flap. He was interviewed 24 months postoperatively to determine his
Autor:
Richard B. Rosse, Barbara L. Schwartz, Jessica A. Burket, Stephen I. Deutsch, Stephanie M. Rosse, Elionora Katz
Publikováno v:
CNS Spectrums. 15:574-578
A 60-year-old patient with a clinical diagnosis of schizophrenia underwent a magnetic resonance imaging (MRI) scan related to the evaluation of isolated seizures that emerged while medicated with clozapine. Unexpectedly, the MRI scan revealed evidenc
Publikováno v:
European Neuropsychopharmacology. 20:207-210
NR2B-subtype-selective antagonists differ from MK-801, a nonselective NMDA receptor antagonist. MK-801 antagonizes electrical seizures at doses as low as 0.1 to 0.18 mg/kg and elicits popping at doses as low as 0.5 mg/kg, whereas ifenprodil and Ro 8-
Publikováno v:
Current Psychiatry Reviews. 5:236-249
The cytoarchitectural defects of schizophrenia are predominantly “mild” alterations of dendrites and cell positioning, which are subtle in comparison to those in the lissencephalies and many presentations of mental retardation. Moreover, they are
Publikováno v:
Psychiatry Research. 167:21-27
Cognitive psychology offers tools to localize the memory processes most vulnerable to disruption in schizophrenia and to identify how patients with schizophrenia best remember. In this research, we used the University of Southern California Repeatabl
Publikováno v:
European Neuropsychopharmacology. 18:814-819
The genetically-inbred Balb/c mouse strain shows heightened sensitivity to the ability of MK-801 (dizocilpine), a noncompetitive NMDA receptor antagonist, to raise the threshold voltage necessary to precipitate tonic hindlimb extension and elicit irr
Autor:
Katrice D. Long, Jessica A. Burket, Brooke L. Gaskins, John Mastropaolo, Richard B. Rosse, Stephen I. Deutsch
Publikováno v:
European Neuropsychopharmacology. 18:565-568
Twenty-four hours after mice are exposed to a single session of forced swimming in cold water, the ability of MK-801 (dizocilpine), a noncompetitive NMDA receptor antagonist, to antagonize electrically precipitated seizures is reduced. Conceivably, t
Publikováno v:
Clinical Neuropharmacology. 31:104-119
Chromatin remodeling is recognized as a major regulator of gene expression that can be influenced by inhibition of epigenetic mechanisms that result in stable, heritable, covalent modifications of histone proteins and their associated DNA. Epigenetic