Zobrazeno 1 - 10
of 648
pro vyhledávání: '"Richard Adams"'
Autor:
Enric Domingo, Sanjay Rathee, Andrew Blake, Leslie Samuel, Graeme Murray, David Sebag-Montefiore, Simon Gollins, Nicholas West, Rubina Begum, Susan Richman, Phil Quirke, Keara Redmond, Aikaterini Chatzipli, Alessandro Barberis, Sylvana Hassanieh, Umair Mahmood, Michael Youdell, Ultan McDermott, Viktor Koelzer, Simon Leedham, Ian Tomlinson, Philip Dunne, Francesca M. Buffa, Timothy S. Maughan, Francesca Buffa, Geoffrey Higgins, Christopher Holmes, Timothy Maughan, Gillies McKenna, James Robineau, Philip Quirke, Matthew Seymour, Richard Kennedy, Mark Lawler, Manuel Salto-Tellez, Peter Campbell, Claire Hardy, Simon Bach, Andrew Beggs, Jean-Baptiste Cazier, Gary Middleton, Dion Morton, Celina Whalley, Louise Brown, Richard Kaplan, Richard Wilson, Richard Adams, Richard Sullivan, Paul Harkin, Steven Walker, Jim Hill, Chieh-Hsi Wu, Dennis Horgan
Publikováno v:
EBioMedicine, Vol 106, Iss , Pp 105228- (2024)
Summary: Background: It is uncertain which biological features underpin the response of rectal cancer (RC) to radiotherapy. No biomarker is currently in clinical use to select patients for treatment modifications. Methods: We identified two cohorts o
Externí odkaz:
https://doaj.org/article/6732596b11c54a618ebd9beb8dd8725c
Autor:
Vicky Coyle, Caroline Forde, Richard Adams, Ashley Agus, Rosemary Barnes, Ian Chau, Mike Clarke, Annmarie Doran, Margaret Grayson, Danny McAuley, Cliona McDowell, Glenn Phair, Ruth Plummer, Dawn Storey, Anne Thomas, Richard Wilson, Ronan McMullan
Publikováno v:
Health Technology Assessment, Vol 28, Iss 14 (2024)
Background Neutropenic sepsis is a common complication of systemic anticancer treatment. There is variation in practice in timing of switch to oral antibiotics after commencement of empirical intravenous antibiotic therapy. Objectives To establish th
Externí odkaz:
https://doaj.org/article/d65b0b41216d4cb6b4b56e317dcd6595
Autor:
Sean M. O'Cathail, Richard Adams, Maria A. Hawkins, David Sebag-Montefiore, Corrie A.M. Marijnen, Emmanouil Fokas
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 43, Iss , Pp 100672- (2023)
Externí odkaz:
https://doaj.org/article/bc8ff86a38d54de1bc04939d282434d6
Autor:
Yanis Tazi, Juan E. Arango-Ossa, Yangyu Zhou, Elsa Bernard, Ian Thomas, Amanda Gilkes, Sylvie Freeman, Yoann Pradat, Sean J. Johnson, Robert Hills, Richard Dillon, Max F. Levine, Daniel Leongamornlert, Adam Butler, Arnold Ganser, Lars Bullinger, Konstanze Döhner, Oliver Ottmann, Richard Adams, Hartmut Döhner, Peter J. Campbell, Alan K. Burnett, Michael Dennis, Nigel H. Russell, Sean M. Devlin, Brian J. P. Huntly, Elli Papaemmanuil
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Classification and risk-stratification for Acute Myeloid Leukemia (AML) at diagnosis are primarily based on cytogenetics and only a few gene mutations. Here, the authors study the genomic landscape of 3653 AML patients and characterize 16 non-overlap
Externí odkaz:
https://doaj.org/article/f0c1b3c2c89c4431b1bfec535238074b
Autor:
Somnath Mukherjee, Christopher N. Hurt, Richard Adams, Andrew Bateman, Kevin M. Bradley, Sarah Bridges, Stephen Falk, Gareth Griffiths, Sarah Gwynne, Christopher M. Jones, Philip J. Markham, Tim Maughan, Lisette S. Nixon, Ganesh Radhakrishna, Rajarshi Roy, Simon Schoenbuchner, Hamid Sheikh, Emiliano Spezi, Maria Hawkins, Thomas D.L. Crosby
Publikováno v:
EClinicalMedicine, Vol 61, Iss , Pp 102059- (2023)
Summary: Background: The utility of early metabolic response assessment to guide selection of the systemic component of definitive chemoradiotherapy (dCRT) for oesophageal cancer is uncertain. Methods: In this multi-centre, randomised, open-label, ph
Externí odkaz:
https://doaj.org/article/138ca15545ee408b9e0a95d7b868e614
Autor:
Louise C Brown, David Fisher, Richard Adams, Jenny Seligmann, Matthew Seymour, Richard Kaplan, Susan D Richman, Philip Quirke, Rachel Butler, Helen Roberts, Janet Graham, Richard H Wilson, Timothy S Maughan
Publikováno v:
Efficacy and Mechanism Evaluation, Vol 9, Iss 9 (2022)
Background: Complex trials with innovative designs are becoming increasingly common and offer the potential to improve patient outcomes in a shorter time frame. There is evidence that patients with colorectal cancer fall into different subgroups with
Externí odkaz:
https://doaj.org/article/a710ce8c7ebb4534b2145ccccfea160e
Autor:
Ameeta Retzer, Melanie Calvert, Stephanie Sivell, Anthony Byrne, Annmarie Nelson, Robin Grant, Elin Baddeley, Hannah Scott, Kathy Seddon, Colin Watts, Linda Dirven, Richard Adams, Olalekan Lee Aiyegbusi, Samantha Cruz Rivera, Pamela Kearns
Publikováno v:
BMJ Open, Vol 12, Iss 9 (2022)
Introduction Primary brain tumours, specifically gliomas, are a rare disease group. The disease and treatment negatively impacts on patients and those close to them. The high rates of physical and cognitive morbidity differ from other cancers causing
Externí odkaz:
https://doaj.org/article/bac60d7de78c4d93b4cdf448d89ba6d2
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Pp 86-104 (2021)
The treatment of locally advanced rectal cancer (LARC) has seen major advances over the past 3 decades, with multimodality treatment now standard of care. Combining surgical resection with radiotherapy and/or chemotherapy can reduce local recurrence
Externí odkaz:
https://doaj.org/article/aed1189cb21c47c9a81231b46b39a839
Autor:
Thomas Hoffman-Walbeck, Richard Adams
Publikováno v:
Journal of Graphic Engineering and Design, Vol 12, Iss 1, Pp 5-9 (2021)
We are presenting an online workflow puzzle, which runs in a browser. The player can put together puzzle pieces to pre-defined production chains. Extensive online help supports the player in laying out the puzzle pieces correctly. The puzzle is based
Externí odkaz:
https://doaj.org/article/ae8f6599df314ff1b0b516cd9e328ee5
Autor:
Séan M. O’Cathail, Steven Davis, Jane Holmes, Richard Brown, Kerry Fisher, Leonard Seymour, Richard Adams, James Good, David Sebag-Montefiore, Tim Maughan, Maria A. Hawkins
Publikováno v:
Radiation Oncology, Vol 15, Iss 1, Pp 1-8 (2020)
Abstract Background Chemoradiotherapy remains the standard of care for locally advanced rectal cancer. Efforts to intensify treatment and increase response rates have yet to yield practice changing results due to increased toxicity and/or absence of
Externí odkaz:
https://doaj.org/article/7ce2e9a046514028ab5f12e3e58832fd