Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Richard A.F Dixon"'
Autor:
Xiaojia Lu, Pengyang Li, Catherine Teng, Peng Cai, Ling Jin, Chenlin Li, Qi Liu, Su Pan, Richard A.F. Dixon, Bin Wang
Publikováno v:
ESC Heart Failure, Vol 8, Iss 5, Pp 3663-3689 (2021)
Abstract Takotsubo cardiomyopathy (TCM), characterized by reversible ventricular dysfunction, has similar mortality to acute coronary syndrome. With the growing interest in the diagnosis of and interventions for TCM, many risk factors had been found
Externí odkaz:
https://doaj.org/article/57c998abb9854543a7c47307c7f18fe5
Publikováno v:
ESC Heart Failure, Vol 8, Iss 1, Pp 555-565 (2021)
Abstract Aims This study sought to determine whether clinical clusters exist in takotsubo cardiomyopathy. Takotsubo cardiomyopathy (TCM) is a heterogeneous disorder with a complex, poorly understood pathogenesis. To better understand the heterogeneit
Externí odkaz:
https://doaj.org/article/e28489886af94fbfa1d6890c8a7a4e56
Autor:
Qiying Dai, Pengyang Li, Abhishek Bose, Peng Cai, Ling Jin, Su Pan, Richard A.F. Dixon, Douglas Laidlaw, Qi Liu
Publikováno v:
The American journal of the medical sciences.
The effects of atrial fibrillation (AF) and its burden on in-hospital mortality in patients with Takotsubo cardiomyopathy (TCM) are unclear. Here, we examined the effect of AF and paroxysmal AF on in-hospital outcomes in patients with TCM.We used ICD
Autor:
Richard A.F. Dixon, Reda E. Girgis
Publikováno v:
Future Cardiology. 3:377-385
Pulmonary arterial hypertension (PAH) is a life-threatening, progressive condition that eventually leads to right heart failure. Endothelin receptor antagonists (ETRAs) have been shown to be a safe and efficacious treatment for PAH. Sitaxsentan is a
Autor:
Robert A. Kirken, Robert M. Langer, Ping Li, Brian Dupre, Lily Feng, Richard A.F. Dixon, Barry D. Kahan, H Podder, Mou-Er Wang, Rongxiang Han, Kurt L. Berens, Stanislaw M. Stepkowski, Wayne W. Hancock
Publikováno v:
Journal of the American Society of Nephrology. 15:2893-2901
Binding of the P-, L-, and E-selectins to sialyl Lewis(x) (sLe(x)) retards circulating leukocytes, thereby facilitating their attachment to the blood vessels of allografts. Whether the selectin inhibitor bimosiamose (BIMO; C(46)H(54)O(16) . 0.25 H(2)
Autor:
Jacqueline A. Jordan, J. R. Ramos-Kelly, E. Yun, Peter A. Ward, Fernando A. Rivera-Chavez, Luis H. Toledo-Pereyra, Richard A.F Dixon, M. Holevar, Thomas Rohs
Publikováno v:
The Journal of Trauma: Injury, Infection, and Critical Care. 49:92-100
Background: The purpose of this study was to investigate the regulatory effect of a small molecule selectin inhibitor in the liver by examining the functional, structural, and survival response of animals subjected to hemorrhagic shock and to determi
Autor:
Luis H. Toledo-Pereyra, Richard A.F Dixon, Peter A. Ward, Jacqueline A. Jordan, Jaime R Ramos-Kelly, Fernando A. Rivera-Chavez
Publikováno v:
Journal of the American College of Surgeons. 189:546-553
Hemorrhage can modify the leukocyte-endothelial cell response leading to tissue injury. The selectin family of adhesion molecules and chemokines mediate the leukocyte-endothelial cell interaction, resulting in neutrophil sequestration and activation.
Autor:
Richard E. Dean, James M. Harkema, Timothy P. Kogan, Luis Horacio Toledo-Pereyra, Richard A.F Dixon, J. M. Palma-Vargas
Publikováno v:
Journal of the American College of Surgeons. 185:365-372
Background: The selectin family of adhesion molecules plays a key role in the neutrophil-mediated injury observed after ischemia and reperfusion. In our study, we investigated the effects of TBC-1269, a novel small-molecule, nonoligosaccharide inhibi
Autor:
Kurt L. Berens, Ryo Gotoh, Yasunobu Nishiwaki, Jun-ichi Suzuki, Mitsuaki Isobe, Hiroshi Ito, Yasuyuki Onai, Masayuki Yoshida, Richard A.F. Dixon
Publikováno v:
European journal of pharmacology. 481(2-3)
Reperfusion injury is related closely to inflammatory reactions such as the activation and accumulation of neutrophils. We investigated the efficacy of a novel small molecule selectin antagonist (bimosiamose) in a rat model of transient left coronary