Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Richard A. Winchurch"'
Publikováno v:
Anesthesiology. 90:1643-1649
Background The neurokinin-1 (NK-1) receptor and its ligand, substance P, are thought to play important roles in nociception and hyperalgesia. This study evaluated the role of the NK-1 receptor in processing noxious stimuli in normal and inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6047cefe3551ac50100f3748e7789aa1
https://doi.org/10.1097/00000542-199906000-00021
https://doi.org/10.1097/00000542-199906000-00021
Autor:
Petra H. Nass, Richard A. Winchurch, Faisal G. Qureshi, Marcin T. Tchorzewski, Patricia J. Gearhart, John W. Harmon, Mark D. Duncan
Publikováno v:
Journal of Surgical Research. 77:99-103
Background.Topical application of growth factors to wounds has proven to be suboptimal in achieving epithelial growth and accelerating healing. We propose transfection of fibroblasts with a gene for acidic fibroblast growth factor (aFGF) which will a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd38b1160c5c158be29794d9146109f0
https://doi.org/10.1006/jsre.1998.5351
https://doi.org/10.1006/jsre.1998.5351
Publikováno v:
Journal of Leukocyte Biology. 63:602-605
Severe traumatic injuries and infections are frequently accompanied by life-threatening shock and are associated with increases in the proinflammatory cytokines, particularly tumor necrosis factor α (TNF-α). The body's first perception of injury is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060f499ed49ae4d1aba3ce5b0cf28d28
https://doi.org/10.1002/jlb.63.5.602
https://doi.org/10.1002/jlb.63.5.602
Publikováno v:
Research in Nursing & Health. 19:511-516
The purpose of this study was to try to elucidate a possible biobehavioral mechanism associated with decreased immune function in trauma patients by determining whether there is an interaction between the effects of ACTH, a stress hormone, and TGF be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6bd812cd983d2d09dc92cd4b12f8115
https://doi.org/10.1002/(sici)1098-240x(199612)19:6<511::aid-nur6>3.0.co
https://doi.org/10.1002/(sici)1098-240x(199612)19:6<511::aid-nur6>3.0.co
Autor:
Pierre F. Laterre, Vladimir A. Odnopozov, Richard J. Traystman, Edward K. Tsybul'kin, Richard A. Winchurch, Michael Breslow
Publikováno v:
Critical Care Medicine. 24:2020-2026
OBJECTIVE To evaluate the effects of hemocarboperfusion on hemodynamics, organ blood flow, and survival in endotoxin shock. DESIGN Prospective, placebo-controlled, animal trial. SETTING Research laboratory in a major university teaching hospital. SUB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f1f24f07d874256d07ef771b141d47
https://doi.org/10.1097/00003246-199612000-00015
https://doi.org/10.1097/00003246-199612000-00015
Autor:
Augustine M.K. Choi, Henry E. Fessler, Richard A. Winchurch, Leo E. Otterbein, Anastasia Kotanidou
Publikováno v:
Journal of Applied Physiology. 81:2304-2311
Kotanidou, Anastasia, Augustine M. K. Choi, Richard A. Winchurch, Leo Otterbein, and Henry E. Fessler. Urethan anesthesia protects rats against lethal endotoxemia and reduces TNF-α release. J. Appl. Physiol. 81(5): 2304–2311, 1996.—Urethan is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::733dd6cc4510cc3018a0ad0d8fb52c55
https://doi.org/10.1152/jappl.1996.81.5.2304
https://doi.org/10.1152/jappl.1996.81.5.2304
Publikováno v:
Journal of Leukocyte Biology. 59:835-839
Normal human polymorphonuclear neutrophils (PMN) undergo rapid apoptosis during in vitro culture. In contrast, apoptosis is inhibited in PMN from patients with severe burns. This inhibition is not an inherent property of the cells but is caused by th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bffa61621ce252b898fc20c39294e8a
https://doi.org/10.1002/jlb.59.6.835
https://doi.org/10.1002/jlb.59.6.835
Autor:
Richard A. Winchurch, Kaori Maeda, Luke O. Schoeniger, Masahiko Shimada, James L. Robotham, T. G. Buchman
Publikováno v:
Anesthesiology. 79:1324-1337
BACKGROUND The hepatic acute phase response (APR) reflects an organism's integrated response to stress. This APR results in augmented synthesis and secretion of specific procoagulants and antiproteases and a complementary decrease in the synthesis an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b909609100d8bd2fee39abd730a2e9
https://doi.org/10.1097/00000542-199312000-00024
https://doi.org/10.1097/00000542-199312000-00024
Publikováno v:
Annals of Surgery. 218:321-327
OBJECTIVE: This study was conducted to determine if reduction of early postburn endotoxemia influences the cytokine cascade, clinical manifestations of sepsis, and mortality rate. SUMMARY BACKGROUND DATA: Translocational endotoxemia has been demonstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92deba5908bebcca78b6c2b0ae68d378
https://doi.org/10.1097/00000658-199309000-00011
https://doi.org/10.1097/00000658-199309000-00011
Publikováno v:
Journal of Burn Care & Rehabilitation. 12:564-568
A new sepsis scale has been developed, and it consists of 13 parameters, each of which is measured daily on a variable point scale. In 41 patients with major burns the Baltimore Sepsis scale correlated well with death or survival, with occurrence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c3e513bc105b8fda774ac1630a2abcb
https://doi.org/10.1097/00004630-199111000-00012
https://doi.org/10.1097/00004630-199111000-00012