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Autor:
Daniel W. Martin
Publikováno v:
The Journal of the Acoustical Society of America. 100:2877
Publikováno v:
J Assoc Res Otolaryngol
Auditory function declines with age, as evidenced by communication difficulties in challenging listening environments for older adults. Declining auditory function may arise, in part, from an age-related loss and/or inactivity of low-spontaneous-rate
Publikováno v:
J Assoc Res Otolaryngol
Age-related hearing loss is a multifactorial condition with effects of aging and environmental exposures that contribute to cochlear pathologies. Metabolic hearing loss involves declines in the endocochlear potential, which broadly reduce cochlear am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::377be2fda2e59e7ce22c6e21aedc2991
https://europepmc.org/articles/PMC8964894/
https://europepmc.org/articles/PMC8964894/
Autor:
Martin, Daniel W.
Publikováno v:
The Journal of the Acoustical Society of America; November 1996, Vol. 100 Issue: 5 p2877-2878, 2p
Autor:
Richard A. Schmiedt, Mark A. Eckert, Morag A. Lewis, Hainan Lang, Kenneth I. Vaden, Kelly C. Harris, Karen P. Steel, Judy R. Dubno, Bradley A. Schulte
Publikováno v:
Hearing Research
Highlights • Presbyacusis presents with metabolic, neural, and/or sensory phenotypes. • Reduced endocochlear potential is likely to be a key contributor to presbyacusis. • Genetic factors contribute to presbyacusis, including single-gene varian
Autor:
Richard A. Schmiedt
Publikováno v:
The Journal of the Acoustical Society of America. 148:2515-2515
Acoustic communication between animals runs the gamut of simple to complex in its dynamic time and frequency structure. Narrow bandwidth codes are often used in noisy environments wherein simple filters can be used to recover the signal under poor si
Publikováno v:
Journal of the Association for Research in Otolaryngology. 14:687-701
Age-related hearing loss (presbyacusis) has a complex etiology. Results from animal models detailing the effects of specific cochlear injuries on audiometric profiles may be used to understand the mechanisms underlying hearing loss in older humans an
Autor:
Nancy Smythe, Daohong Zhou, Richard A. Schmiedt, Hainan Lang, Vinu Jyothi, Bradley A. Schulte, Amanda C. LaRue, Manna Li, Lauren A. Kilpatrick
Publikováno v:
The Journal of Comparative Neurology. 518:3254-3271
With the exception of humans, the somata of type I spiral ganglion neurons (SGNs) of most mammalian species are heavily myelinated. In an earlier study, we used Ly5.1 congenic mice as transplant recipients to investigate the role of hematopoietic ste
Autor:
Vinu Jyothi, Bradley A. Schulte, Nancy Smythe, Hainan Lang, Judy R. Dubno, Richard A. Schmiedt
Publikováno v:
Journal of the Association for Research in Otolaryngology. 11:419-434
Gerbils aged in quiet show a decline of the endocochlear potential (EP) and elevated auditory nerve compound action potential (CAP) thresholds. However, establishing a direct relationship between an age-related reduction in the EP and changes in the