Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Richard A. Neese"'
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 11, Pp 2562-2574 (2006)
Newly synthesized triglyceride (TG) may exit the liver immediately as VLDL-TG or be stored and secreted after a delay. We quantified the contributions from plasma NEFA, diet, and de novo lipogenesis (DNL) to VLDL-TG via immediate and delayed pathways
Externí odkaz:
https://doaj.org/article/59377fde15de4f8f837a8a928166daf6
Autor:
Lisa C. Hudgins, Marc K. Hellerstein, Cynthia E. Seidman, Richard A. Neese, Jolanta D. Tremaroli, Jules Hirsch
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 4, Pp 595-604 (2000)
We previously reported that a eucaloric, low fat, liquid formula diet enriched in simple carbohydrate markedly increased the synthesis of fatty acids in lean volunteers. To examine the diet sensitivity of obese subjects, 7 obese and 12 lean volunteer
Externí odkaz:
https://doaj.org/article/0cd564b0deca46cbbdd3089195f1a6c0
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 12, Pp 2319-2328 (1998)
We used [2-13C1]glycerol to characterize very low density lipoprotein (VLDL)-triglyceride kinetics and intrahepatic glycerol metabolism in normal men (n = 4) after alcohol (EtOH) ingestion. [2-13C1]glycerol was infused before and after the consumptio
Externí odkaz:
https://doaj.org/article/22185f040caf4859ac6c394fb6ad24a3
Autor:
Aline Baday, Jules Hirsch, Richard A. Neese, Cynthia E. Seidman, Marc K. Hellerstein, Jolanta D. Tremaroli, Thomas S. Parker, Lisa C. Hudgins, Daniel M. Levine
Publikováno v:
The Journal of Nutritional Biochemistry. 19:237-245
Hepatic de novo lipogenesis (DNL) is markedly stimulated in humans by low-fat diets enriched in simple sugars. However, the dietary responsiveness of the key enzyme controlling DNL in human adipose tissue, fatty acid synthase (FAS), is uncertain.Adip
Autor:
Mohamad Awada, Yoo-Kyeong Kim, James L Gardner, Valerie Schade-Serin, Marc K. Hellerstein, Robert Busch, Lisa M. Misell, Michelle L. Collins, Carine Beysen, Richard A. Neese, Michael E. Marino
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1760:730-744
In vivo measurements of protein synthesis using isotope-labeled amino acids (AAs) are hampered by the heterogeneity of AA pools and, for slow turnover proteins, the difficulty and expense of long-term labeling. Continuous oral heavy water (2H2O) labe
Autor:
Marc K. Hellerstein, Christine M. Chai, Richard A. Neese, Benito O. De Lumen, Elaine A. Hsieh
Publikováno v:
Journal of Investigative Dermatology. 123:530-536
A heavy water (2H2O) labeling method recently developed to measure cell proliferation in vivo is applied here to the measurement of murine epidermal cell turnover and to investigate conditions in which keratinocyte proliferation is either inhibited o
Autor:
Elizabeth Murphy, Fernando Antelo, Marc K. Hellerstein, A. Agarwal, Richard A. Neese, Scott M. Turner, Tiffany Thomas, C. Go
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 285:E790-E803
A method is presented for measurement of triglyceride (TG) synthesis that can be applied to slow-turnover lipids. The glycerol moiety of TG is labeled from2H2O, and mass isotopomer distribution analysis (MIDA) is applied. Mice and rats were given 4-8
Autor:
Marc K. Hellerstein, Rebecca A. Hoh, Mary Beth Hanley, Denise Cesar, Daniel Lee, Richard A. Neese, Joseph M. McCune
Publikováno v:
Journal of Clinical Investigation. 112:956-966
Autor:
R. Hoh, Richard A. Neese, M. Christiansen, Denise Cesar, Marc K. Hellerstein, Lisa M. Misell, Joseph M. McCune, A. Chu, Scott M. Turner, Fernando Antelo, Jeewon Kim, A. Strawford
Publikováno v:
Proceedings of the National Academy of Sciences. 99:15345-15350
We describe here a method for measuring DNA replication and, thus, cell proliferation in slow turnover cells that is suitable for use in humans. The technique is based on the incorporation of 2 H 2 O into the deoxyribose (dR) moiety of purine deoxyri
Autor:
Richard A. Neese, K Caldwell, H Schweingrubber, Cedric H.L. Shackleton, C Papageorgopoulos, Marc K. Hellerstein
Publikováno v:
Analytical Biochemistry. 309:1-10
We investigated a novel strategy for measuring the synthesis rate of proteins in skeletal and cardiac muscle. Mass isotopomer distribution analysis allows measurement of the isotopic enrichment of the true biosynthetic precursor for proteins (tRNA-am