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pro vyhledávání: '"Richard A. Marlar"'
Autor:
Richard A. Marlar
Publikováno v:
Seminars in Thrombosis and Hemostasis.
Thrombophilia is a complex disease process, clinically manifesting in various forms of venous thromboembolism. Although both genetic and acquired (or environmental) risks factors have been reported, the presence of a genetic defect (antithrombin [AT]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b62a0655f15d6f16acca6b6016a7579
https://doi.org/10.1055/s-0043-1764468
https://doi.org/10.1055/s-0043-1764468
Publikováno v:
The Journal of Applied Laboratory Medicine. 7:794-802
Background One of the most complex risk factors for the laboratory assessment of thrombophilia is Protein S (PS). The testing algorithm for PS employs the plasma-based assays of free PS antigen, total PS antigen, and PS activity creating a complex di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea20dfb2b4c290327d32c7dd70207427
https://doi.org/10.1093/jalm/jfab175
https://doi.org/10.1093/jalm/jfab175
Autor:
Richard A. Marlar
Publikováno v:
Methods in Molecular Biology ISBN: 9781071631744
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47215738521bb3def98eaa8e0cbf3900
https://doi.org/10.1007/978-1-0716-3175-1_10
https://doi.org/10.1007/978-1-0716-3175-1_10
Autor:
Josefin Ahnström, Björn Dahlbäck, Elisabetta Castoldi, Richard A. Marlar, Herm Jan M. Brinkman
Publikováno v:
Journal of Thrombosis and Haemostasis, 19(1), 281-286. Wiley
Hereditary deficiencies of protein S (PS) increase the risk of thrombosis. However, assessing the plasma levels of PS is complicated by its manifold physiological interactions, while the large inter-individual variability makes it problematic to esta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a58f7138caebadcdce1cb9a14c891d
https://cris.maastrichtuniversity.nl/en/publications/f98462cc-f8c7-471f-b05d-381205764026
https://cris.maastrichtuniversity.nl/en/publications/f98462cc-f8c7-471f-b05d-381205764026
Publikováno v:
Journal of Thrombosis and Haemostasis. 18:271-277
Inherited protein C (PC) deficiency increases risk of venous thromboembolism (VTE) by 5 to 10-fold in thrombosis-prone families; however, heterozygous PC deficiency alone does not determine that a subject has thrombophilia. Protein C deficient subjec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b7ececfbb00773cad0ee6111a4aab08
https://doi.org/10.1111/jth.14667
https://doi.org/10.1111/jth.14667
Publikováno v:
International journal of laboratory hematologyREFERENCE. 44(2)
INTRODUCTION Management of hemophilia A has changed significantly in the past few years with the expansion of new and/or modified products as treatment options. Unfortunately, many of the standard factor VIII assays do not always accurately measure a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::950c2610f895e237637db26729b6cc7c
https://pubmed.ncbi.nlm.nih.gov/34786864
https://pubmed.ncbi.nlm.nih.gov/34786864
Publikováno v:
European Journal of Haematology
Treatment of haemophilia A/B patients comprises factor VIII (FVIII) or factor IX (FIX) concentrate replacement therapy, respectively. FVIII and FIX activity levels can be measured in clinical laboratories using one‐stage activated partial thrombopl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b6297911cf2c6d63a2cefc6ab92edfb
https://doi.org/10.1111/ejh.13339
https://doi.org/10.1111/ejh.13339
Autor:
Richard A. Marlar, Robert C. Gosselin
Publikováno v:
Seminars in Thrombosis and Hemostasis. 45:433-448
Many preanalytical variables may affect the results of routine coagulation assays. While advances in laboratory instrumentation have partially addressed the laboratory's ability to recognize some of these variables, there remains an increased relianc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef2756c200ab4d3e505723358ea3c027
https://doi.org/10.1055/s-0039-1692700
https://doi.org/10.1055/s-0039-1692700
Publikováno v:
International Journal of Laboratory Hematology. 41:162-169
In the coagulation laboratory, much emphasis has been placed on rapid and accurate testing; however, spurious results that are inaccurate and do not reflect the actual status of the patient can potentially lead to an incorrect diagnosis and altered i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04d1b58541ea2400d65d20aaab74030
https://doi.org/10.1111/ijlh.12989
https://doi.org/10.1111/ijlh.12989
Autor:
Steve Kitchen, Dorothy M. Adcock, Ray Dauer, Ann‐Helen Kristoffersen, Giuseppe Lippi, Ian Mackie, Richard A. Marlar, Sukesh Nair
Publikováno v:
International journal of laboratory hematologyReferences. 43(4)
This guidance document has been prepared on behalf of the International Council for Standardisation in Haematology (ICSH). The aim of the document is to provide guidance and recommendations for collection of blood samples for coagulation tests in cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::888bc65b3a007cb7535a45a5225d2f77
https://pubmed.ncbi.nlm.nih.gov/34097805
https://pubmed.ncbi.nlm.nih.gov/34097805