Zobrazeno 1 - 10
of 230
pro vyhledávání: '"Richard A. Kramer"'
Autor:
Qinrong Zhang, Yuhan Yang, Kevin J Cao, Wei Chen, Santosh Paidi, Chun-hong Xia, Richard H Kramer, Xiaohua Gong, Na Ji
Publikováno v:
eLife, Vol 12 (2023)
The retina, behind the transparent optics of the eye, is the only neural tissue whose physiology and pathology can be non-invasively probed by optical microscopy. The aberrations intrinsic to the mouse eye, however, prevent high-resolution investigat
Externí odkaz:
https://doaj.org/article/933482e627334f09b5077b1797c15202
Publikováno v:
iScience, Vol 24, Iss 10, Pp 103094- (2021)
Summary: FeRIC (Ferritin iron Redistribution to Ion Channels) is a magnetogenetic technique that uses radiofrequency (RF) alternating magnetic fields to activate the transient receptor potential channels, TRPV1 and TRPV4, coupled to cellular ferritin
Externí odkaz:
https://doaj.org/article/2bac306fa0e54c2d9737bbd41084dbf1
Autor:
Sergei Nikonov, Natalia Dolgova, Raghavi Sudharsan, Ivan Tochitsky, Simone Iwabe, Jose-Manuel Guzman, Russell N. Van Gelder, Richard H. Kramer, Gustavo D. Aguirre, William A. Beltran
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2711 (2022)
Photopharmacological compounds such as azobenzene-based photoswitches have been shown to control the conductivity of ionic channels in a light-dependent manner and are considered a potential strategy to restore vision in patients with end-stage photo
Externí odkaz:
https://doaj.org/article/5919a5885bde42f29503b6d35b955585
Autor:
Robert Paul Malchow, Boriana K. Tchernookova, Ji-in Vivien Choi, Peter J. S. Smith, Richard H. Kramer, Matthew A. Kreitzer
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
There is significant evidence to support the notion that glial cells can modulate the strength of synaptic connections between nerve cells, and it has further been suggested that alterations in intracellular calcium are likely to play a key role in t
Externí odkaz:
https://doaj.org/article/a3ac6bb318ba4996b516a85772e6d8cc
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Vision impairment and blindness in humans are most frequently caused by the degeneration and loss of photoreceptor cells in the outer retina, as is the case for age-related macular degeneration, retinitis pigmentosa, retinal detachment and many other
Externí odkaz:
https://doaj.org/article/53be21eaa2d047a8a7a24930fd342d61
Autor:
Ryan J Vaden, Jose Carlos Gonzalez, Ming-Chi Tsai, Anastasia J Niver, Allison R Fusilier, Chelsea M Griffith, Richard H Kramer, Jacques I Wadiche, Linda Overstreet-Wadiche
Publikováno v:
eLife, Vol 9 (2020)
Parvalbumin-expressing interneurons (PVs) in the dentate gyrus provide activity-dependent regulation of adult neurogenesis as well as maintain inhibitory control of mature neurons. In mature neurons, PVs evoke GABAA postsynaptic currents (GPSCs) with
Externí odkaz:
https://doaj.org/article/325209460c5c45cfac84313a7ec71f89
Autor:
Michael H. Berry, Amy Holt, Joshua Levitz, Johannes Broichhagen, Benjamin M. Gaub, Meike Visel, Cherise Stanley, Krishan Aghi, Yang Joon Kim, Kevin Cao, Richard H. Kramer, Dirk Trauner, John Flannery, Ehud Y. Isacoff
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
To restore sight after retinal degeneration, one approach is to express light-sensitive proteins in remaining cells. Here the authors combine a light-sensitive engineered G protein-coupled receptor and ion channels to restore ON and OFF responses as
Externí odkaz:
https://doaj.org/article/633814130c744076adf5b920ac4c46b7
Autor:
Yuhan Yang, Qinrong Zhang, Kevin J Cao, Wei Chen, Santosh Paidi, Chun-hong Xia, Richard H Kramer, Xiaohua Gong, Na Ji
Publikováno v:
eLife. 12
The retina, behind the transparent optics of the eye, is the only neural tissue whose physiology and pathology can be non-invasively probed by optical microscopy. The aberrations intrinsic to the mouse eye, however, prevent high-resolution investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::699d1357a20fe458f6e9368dcf0a66af
https://doi.org/10.7554/elife.84853
https://doi.org/10.7554/elife.84853
Publikováno v:
Bioelectricity. 4:108-116
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aec883687d86c72c1be091daaa2892ef
https://doi.org/10.1089/bioe.2022.0017
https://doi.org/10.1089/bioe.2022.0017
