Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Richard A. Knazek"'
Publikováno v:
Journal of Immunological Methods. 127:29-37
Human tumor infiltrating lymphocytes (TIL) from metastatic melanoma of six patients were grown using a new hollow fiber bioreactor system. After inoculating 0.35–10 × 10 8 TIL into the extra-fiber space (EFS), each Cellmax bioreactor was perfused
Autor:
Richard A. Knazek
Publikováno v:
Diabetes Technology & Therapeutics. 4:551-552
Autor:
Sue C. Liu, Richard A. Knazek
Publikováno v:
Prostaglandins, Leukotrienes and Medicine. 12:159-167
Mammary carcinomata were induced by administration of nitrosomethyl urea to female Buffalo rats. Specific binding of PGE1 to the 15,000 xg membranes obtained from these tumors was maximal after approximately 60 minutes of incubation at 15 degrees C.
Publikováno v:
JNCI: Journal of the National Cancer Institute. 58:419-422
An established line of human breast carcinoma, MCF-7, when cultured within the artificial capillary system, formed solid masses of tissue. Acinar and ductular patterns developed, having the ultrastructural appearance of breast tissue that responds to
Publikováno v:
Prostaglandins and Medicine. 6:403-411
Indomethacin suppressed the numbers of prolactin receptors detectable in the liver membranes of both male and female C 3 H mice. This occurred in a dose-dependent fashion with 7.5 μg/gm body weight injected every 4 hours exerting a maximal effect wi
Publikováno v:
AIDS Research. 2:73-76
Growth Hormone Causes Rapid Induction of Lactogenic Receptor Activity in the Snell Dwarf Mouse Liver
Autor:
Sue C. Liu, Robert L. Graeter, Philip C. Wright, Ellen B. Gould, Ronald H. Lewis, Joyce A. Keller, Richard A. Knazek, Janine R. Mayer
Publikováno v:
Endocrinology. 103:1590-1596
The Snell dwarf mouse (dw/dw) has no detectable PRL-binding sites in the microsomal fractions of its liver. Both bGH and bPRL, purified by preparative gel electrophoresis, induce PRL-binding sites when injected into dw/dw. Intraperitoneal injection o
Publikováno v:
International Journal of Cancer. 36:143-152
The metabolism of arachidonic acid was investigated by radioimmunoassay and chromatographic techniques in 5 sarcomas and one embryonal carcinoma of human origin maintained as transplantable tumors in nude mice. The results obtained indicate that: (1)
Publikováno v:
Endocrinology. 101:50-58
Lactogenic binding sites were shown to be absent in the livers of Snell dwarf mice (dw/dw). Phenotypically normal littermates (DW/?), however, bound oPRL with an apparent affinity constant, Ka, 15 × 109M−1 and possessed quantities of binding sites
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 66:33-38
Studies using cultured human adrenocortical cells were performed to determine if the immune modulation of glucocorticoid production previously described in animal studies also occurs in humans. Human monocytes significantly increased (P less than 0.0