Zobrazeno 1 - 10
of 227
pro vyhledávání: '"Richard A. Hubner"'
Autor:
Victoria Foy, Mairéad G. McNamara, Juan W. Valle, Angela Lamarca, Julien Edeline, Richard A. Hubner
Publikováno v:
Current Oncology, Vol 30, Iss 9, Pp 8665-8685 (2023)
The treatment of advanced unresectable HCC (aHCC) remains a clinical challenge, with limited therapeutic options and poor prognosis. The results of IMbrave150 and HIMALAYA have changed the treatment paradigm for HCC and established immune checkpoint
Externí odkaz:
https://doaj.org/article/e6075971c8d843248347bb5a70df88af
Autor:
Mairéad G. McNamara, Jayne Swain, Zoe Craig, Rohini Sharma, Olusola Faluyi, Jonathan Wadsley, Carys Morgan, Lucy R. Wall, Ian Chau, Nick Reed, Debashis Sarker, Jane Margetts, Daniel Krell, Judith Cave, Sharmila Sothi, Alan Anthoney, Christopher Bell, Alkesh Patel, Jamie B. Oughton, David A. Cairns, Wasat Mansoor, Angela Lamarca, Richard A. Hubner, Juan W. Valle
Publikováno v:
EClinicalMedicine, Vol 60, Iss , Pp 102015- (2023)
Summary: Background: The prognosis for patients with poorly-differentiated extra-pulmonary neuroendocrine carcinoma (PD-EP-NEC) is poor. A recognised first-line (1L) treatment for advanced disease is etoposide/platinum-based chemotherapy with no stan
Externí odkaz:
https://doaj.org/article/17e61c62deeb4eef9d3d7c4b9df3c376
Selection of Chemotherapy in Advanced Poorly Differentiated Extra-Pulmonary Neuroendocrine Carcinoma
Publikováno v:
Cancers, Vol 15, Iss 20, p 4951 (2023)
Extra-pulmonary poorly differentiated neuroendocrine carcinoma is rare, and evidence for treatment has been limited. In this article, the evidence behind the cytotoxic chemotherapy choices used for metastatic or unresectable EP-PD-NEC is reviewed. In
Externí odkaz:
https://doaj.org/article/52aff99b794d49fea3a08e4b469b4cba
Autor:
Sarah Clelland, Christina L. Nuttall, Helen E. Stott, Joseph Cope, Natalie L. Barratt, Kelly Farrell, Manyi V. Eyong, Jack P. Gleeson, Angela Lamarca, Richard A. Hubner, Juan W. Valle, Mairéad G. McNamara
Publikováno v:
Healthcare, Vol 11, Iss 20, p 2802 (2023)
Advanced pancreatic cancer is associated with a poor prognosis, often less than 1 year. Honest prognosis discussions guide early community palliative care services input, facilitating timely advance care planning and improving quality of life. The ai
Externí odkaz:
https://doaj.org/article/1ae44ad74f7743bb8ce29cca07591869
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 15 (2023)
Neuroendocrine neoplasms (NENs) are rare malignancies arising most commonly in the gastrointestinal and bronchopulmonary systems. Neuroendocrine carcinomas (NECs) are a subgroup of NENs characterised by aggressive tumour biology, poor differentiation
Externí odkaz:
https://doaj.org/article/733af2b9707a4c1d8e811a72c0688cc5
Autor:
Matthew D. Robinson, Mairéad G. McNamara, Hamish W. Clouston, Paul A. Sutton, Richard A. Hubner, Juan W. Valle
Publikováno v:
Cancers, Vol 15, Iss 15, p 3781 (2023)
As part of routine cancer care, patients may undergo elective surgery with the aim of long-term cure. Some of these patients will receive systemic anti-cancer therapy (SACT) in the neoadjuvant and adjuvant settings. The majority of patients, usually
Externí odkaz:
https://doaj.org/article/349d6a2a55804aa7b691ba2e5cdd9780
Autor:
Simon Gray, Octave Letissier, Constance d’Abrigeon, Dinakshi Shah, Stephen Wardell, Olusola Faluyi, Angela Lamarca, Richard A. Hubner, Julien Edeline, Juan W. Valle, Mairéad G. McNamara
Publikováno v:
Cancers, Vol 15, Iss 11, p 3047 (2023)
Phase 3 trials have established standard first-line (1L) and 2L systemic therapy options for patients with advanced biliary cancer (ABC). However, a standard 3L treatment remains undefined. Clinical practice and outcomes for 3L systemic therapy in pa
Externí odkaz:
https://doaj.org/article/06599507217b4205b17c658adad5e0ef
Autor:
Lindsay E. Carnie, Dinakshi Shah, Kate Vaughan, Zainul Abedin Kapacee, Lynne McCallum, Marc Abraham, Alison Backen, Mairéad G. McNamara, Richard A. Hubner, Jorge Barriuso, Loraine Gillespie, Angela Lamarca, Juan W. Valle
Publikováno v:
Cancers, Vol 15, Iss 8, p 2277 (2023)
Introduction: Pancreatic exocrine insufficiency (PEI) in patients with advanced pancreatic cancer (aPC) is well documented, but there is no consensus regarding optimal screening. Methods and analysis: Patients diagnosed with aPC referred for palliati
Externí odkaz:
https://doaj.org/article/502860213dce4888aa403d5ff65bd4fa
Autor:
Rille Pihlak, Melissa Frizziero, Soo Yit Gustin Mak, Christina Nuttall, Angela Lamarca, Richard A. Hubner, Juan W. Valle, Mairéad G. McNamara
Publikováno v:
Cancers, Vol 15, Iss 3, p 738 (2023)
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with a poor prognosis and significant symptom burden. This prospective observational study aimed to evaluate expectations and priorities of patients with advanced PDAC and their clinicia
Externí odkaz:
https://doaj.org/article/fb061ff45e3f425f8c22a4d322a2a24b
Autor:
Simon Gray, Angela Lamarca, Julien Edeline, Heinz-Josef Klümpen, Richard A. Hubner, Mairéad G. McNamara, Juan W. Valle
Publikováno v:
Cancers, Vol 14, Iss 7, p 1789 (2022)
Perihilar cholangiocarcinoma (pCCA) is the anatomical sub-group of biliary tract cancer (BTC) arising between the second-order intrahepatic bile ducts and the cystic duct. Together with distal and intrahepatic cholangiocarcinoma (dCCA and iCCA; origi
Externí odkaz:
https://doaj.org/article/69515cdd8cc04a1593b520d4d0d57c71